Lichen planus may mess with your sense of smell and taste, study finds
NCT ID NCT07570706
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study looked at whether lichen planus, a chronic inflammatory condition, affects smell and taste. 88 adults (patients and healthy controls) took smell and taste tests and had oral and nasal exams. The goal was to see if mucosal involvement is linked to sensory changes, which could improve future care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors better understand and manage smell and taste problems in people with lichen planus.
- What could go wrong
- This is a small, completed observational study, so it only shows possible links—not proof of cause or treatment. Results may not apply to everyone with lichen planus.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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88 people
The number who actually took part.
- Started
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Jan 2026
- Finished
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Apr 2026
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study includes adults aged 18-65 years with a clinical diagnosis of lichen planus, as well as healthy volunteers without lichen planus. Participants were assessed for smell and taste function, and the patient group also underwent oral and nasal mucosal examinations, including nasal endoscopy. Both male and female participants were included.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Age 18-65 years Clinically diagnosed with lichen planus (patient group) Healthy individuals without lichen planus (control group) Willing and able to provide informed consent Exclusion Criteria: Nasal septum deviation Nasal polyposis, congenital olfactory dysfunction, chronic rhinosinusitis, or allergic rhinitis History of head trauma History of nasal or paranasal surgery Psychiatric or neurological disorders (e.g., Parkinson's disease, Alzheimer's disease) Persistent loss of smell following COVID-19 infection Pregnancy or breastfeeding
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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S.B.U. Istanbul Training and Research Hospital
Istanbul, Istanbul, 34098, Turkey (Türkiye)
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