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MRI may replace needle biopsy for muscle disease diagnosis

NCT ID NCT01432613

First seen Mar 31, 2026 · Last updated Jun 22, 2026 · Updated 11 times

Summary

This study looked at whether whole body MRI can accurately diagnose inflammatory myopathies—a group of muscle diseases causing weakness and damage. Researchers compared MRI results with muscle biopsies in 139 people suspected of having these conditions. If MRI proves reliable, it could offer a less invasive way to diagnose these serious diseases.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHU Amiens Nord

    Amiens, 80054, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, MRI could become a reliable, non-invasive tool to diagnose inflammatory myopathies faster and more accurately.

What could go wrong

This is a completed diagnostic accuracy study, not a treatment trial. MRI may not replace biopsy entirely, and results depend on patient selection and MRI quality.

Conditions

The condition(s) this trial relates to.

allergic disease dermatomyositis inclusion body myositis myositis disease polymyositis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.