POLYMYOSITIS

This early-stage trial is testing whether modified immune cells called CAR-T cells can help control severe autoimmune diseases like lupus, scleroderma, and muscle inflammation diseases. The treatment involves collecting a patient's own immune cells, genetically modifying them to …

This study aims to understand the long-term safety and effectiveness of the drug dazukibart for adults with dermatomyositis or polymyositis, two rare diseases that cause painful muscle weakness and inflammation. The trial is open to people who previously completed a related 52-we…

This early-stage study is testing a new drug called SAR448501 in adults with moderate-to-severe lupus or rheumatoid arthritis who haven't gotten enough relief from their current treatments. The main goal is to find safe dose levels and see how the drug behaves in the body. About …

This study aims to understand whether certain environmental exposures—like infections, chemicals, or stressful events—might trigger autoimmune muscle diseases called myositis. Researchers will compare 580 people with myositis to healthy volunteers, collecting blood, dust samples,…

This study aims to understand what research matters most to people living with rare muscle diseases called myositis. Researchers will collect perspectives from 700 patients and caregivers worldwide through online surveys and discussions. The goal is to create a list of patient-pr…

This study is creating a large collection of health information and biological samples from people with various rheumatic diseases like rheumatoid arthritis and lupus. The goal is to help researchers better understand what causes these conditions and how they progress over time. …

This study aims to better understand the causes and effects of rare inflammatory muscle diseases like dermatomyositis and polymyositis. Researchers will observe up to 1,200 participants, including both patients and healthy volunteers, over time. The goal is to learn how these dis…