POLYMYOSITIS

This study tested whether a weekly injection called KZR-616 could safely improve muscle strength and overall disease activity in adults with active polymyositis or dermatomyositis. Twenty-five participants received either the drug or a placebo for 16 weeks, then switched to the o…

This study followed patients with polymyositis or dermatomyositis who had previously participated in a related trial. It aimed to assess the long-term safety and effectiveness of weekly KZR-616 injections over up to 96 weeks of treatment. The goal was to see if the drug could hel…

This study tested whether a whole-body MRI scan could accurately diagnose serious inflammatory muscle diseases like polymyositis and dermatomyositis. Researchers enrolled 139 patients with suspected muscle disease to compare MRI results against the standard muscle biopsy test. Th…

This study tested whether a personalized, 4-week exercise program could improve daily function and quality of life for people with dermatomyositis or polymyositis. 80 adults with stable muscle weakness were randomly assigned to either receive the exercise program or continue with…

This study had two main goals. First, it aimed to see if a simple, quick test called the Myositis Functional Index-3 (FI-3) gives results similar to more complex and expensive muscle function tests. Second, it tested whether a 12-week program of repetitive task training exercises…

This study aimed to discover what causes rare autoimmune diseases that attack muscles and connective tissues, like polymyositis and dermatomyositis. Researchers studied 719 people, including patients and their family members, to look for genetic clues and environmental triggers l…