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5,000 patients join Yale's quest to crack rheumatic disease mysteries

NCT ID NCT04402086

First seen Feb 17, 2026 · Last updated Jun 21, 2026 · Updated 18 times

Summary

This study is building a large registry and biorepository of 5,000 adults with various rheumatic diseases like rheumatoid arthritis, lupus, and scleroderma. Researchers at Yale University will collect medical data and biological samples over time to better understand these conditions and find links between outcomes and biomarkers. The goal is to support future research that could lead to improved diagnosis and treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Yale New Haven Hospital

    RECRUITING

    New Haven, Connecticut, 06510, United States

    Contact Phone: •••-•••-••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this registry could help researchers discover new biomarkers and improve understanding of rheumatic diseases, pointing toward better diagnostics or treatments.

What could go wrong

This is an observational registry, not a treatment trial. It may not directly lead to new therapies, and results depend on participant diversity and data quality.

Conditions

The condition(s) this trial relates to.

adult-onset Still disease ankylosing spondylitis antiphospholipid syndrome Behcet disease dermatomyositis diffuse scleroderma Giant Cell Arteritis Lyme disease mixed connective tissue disease polymyalgia rheumatica polymyositis psoriatic arthritis reactive arthritis rheumatic disorder rheumatoid arthritis sarcoidosis Sjogren syndrome systemic lupus erythematosus systemic sclerosis Undifferentiated Connective Tissue Diseases

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.