GIANT CELL ARTERITIS

This study tests whether the drug abatacept can help people with giant cell arteritis, a condition that causes inflamed blood vessels. About 78 adults with newly diagnosed or relapsing disease will receive either abatacept or a placebo for up to 12 months. The goal is to see if t…

This study tests whether taking extra hydrocortisone during stressful times (like illness or emotional strain) improves quality of life, especially fatigue, in people with polymyalgia rheumatica (PMR) or giant cell arteritis (GCA). Participants are 50 or older, on low-dose predni…

This study looks at whether a lower-resolution MRI can reliably diagnose giant cell arteritis, a serious condition that inflames arteries and can cause blindness or stroke. Researchers will compare different MRI scans in 133 people suspected of having the disease. If successful, …

This study follows 400 adults diagnosed with giant cell arteritis or polymyalgia rheumatica to track serious long-term complications, including aortic aneurysms and side effects from steroid treatment. Researchers will monitor participants over time to better understand how often…

This study follows up to 4,000 people with or at risk for vasculitis—a group of diseases that cause blood vessel inflammation—to learn how the condition develops and changes over time. Participants provide blood, urine, and imaging samples, and some have regular check-ups every 3…

This study is building a large collection of health information and blood samples from 5,000 adults with rheumatic diseases like rheumatoid arthritis, lupus, and scleroderma. Researchers will use this data to find links between patient outcomes and biological markers. The goal is…

This study looks at whether ultrasound scans of the temporal and axillary arteries can help predict relapses in people with giant cell arteritis, a condition that causes inflamed blood vessels. Researchers will follow 100 participants to see if certain ultrasound findings are lin…

This study collects existing tissue samples from 1,000 people with various forms of vasculitis, a group of rare blood vessel diseases. Researchers will analyze the samples along with health data to find genes and other factors that cause these conditions. The goal is to spark new…

This study collects DNA samples and health information from 1,000 people with vasculitis (a group of rare blood vessel diseases). Researchers will analyze the data to find genes that increase the risk of developing these conditions. The goal is to better understand what causes va…

This study tests whether MRI scans can reliably detect inflammation in the arteries that supply the head, brain, and eyes in people with suspected giant cell arteritis (GCA). Researchers will enroll 400 adults aged 50 and older who have new or worsening symptoms and high inflamma…