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New MRI method may replace scalpel for diagnosing head artery disease

NCT ID NCT05865054

First seen Oct 31, 2025 · Last updated Jun 22, 2026 · Updated 30 times

Summary

This study is testing whether a special MRI scan can detect inflammation in the arteries that supply blood to the head, brain, and eyes. Researchers will enroll 400 people aged 50 and older with suspected giant cell arteritis, a condition that can cause headaches, vision loss, and stroke. The goal is to see if MRI can accurately diagnose the disease without needing a surgical biopsy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • 3400 Civic Center Blvd

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Mayo Building and Gonda Building

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Joseph's Healthcare Hamilton

    NOT_YET_RECRUITING

    Hamilton, Ontario, L8G 5E4, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Wuerzburg

    NOT_YET_RECRUITING

    Würzburg, Würzburg, 97080, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Magnetic Resonance Imaging (MRI) with contrast

What this could lead to

If successful, MRI could become a reliable, non-invasive way to diagnose giant cell arteritis, replacing or reducing the need for surgical biopsies.

What could go wrong

This is an observational study, not a treatment trial. MRI may not be accurate enough to replace current diagnostic methods, and results may vary across different medical centers.

Conditions

The condition(s) this trial relates to.

Giant Cell Arteritis temporal arteritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.