ANKYLOSING SPONDYLITIS

This study tests a new medicine called LNK01001 for people with active ankylosing spondylitis, a type of arthritis that causes back pain and stiffness. About 352 adults who haven't gotten enough relief from standard anti-inflammatory drugs will receive either LNK01001 or a placeb…

This study tests whether taking fecal transplants (processed stool from healthy donors) in capsule form can help control inflammation in people newly diagnosed with rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, Crohn's disease, or ulcerative colitis. Two hund…

This study tests a new drug called 608 in 500 adults with active ankylosing spondylitis, a type of arthritis that causes back pain and stiffness. Participants will receive either 608 or a placebo to see if the drug improves symptoms like pain and mobility. The goal is to find a b…

This study is for people with ankylosing spondylitis (a type of arthritis that affects the spine) who have never used certain biologic drugs. It will test how well secukinumab works and how safe it is. About 70 participants will be observed over time to see if their symptoms and …

This study tests a new, ultrasound-guided acupotomy technique to reduce disease activity in people with ankylosing spondylitis, a type of arthritis that causes back pain and stiffness. About 60 adults with active disease will receive the treatment to see if it improves symptoms l…

This study looks at whether a gluten-free diet can reduce disease activity and improve quality of life in people with ankylosing spondylitis, a type of arthritis that affects the spine. Researchers will also check if the diet helps heal the gut. Sixty adults with stable treatment…

This study is testing a new educational tool designed for people with melanoma who also have an autoimmune disease (like rheumatoid arthritis or Crohn's disease). The tool helps patients understand immune checkpoint inhibitor drugs and their possible side effects. Researchers wil…

This study aims to understand how well shoulder replacements work over the long term by following up to 20,000 people for at least 10 years. Participants include those who have already had or are scheduled for shoulder replacement due to conditions like arthritis, rotator cuff te…

This study is building a large collection of health information and blood samples from 5,000 adults with rheumatic diseases like rheumatoid arthritis, lupus, and scleroderma. Researchers will use this data to find links between patient outcomes and biological markers. The goal is…

This study collects tissue and blood samples from 300 people with autoimmune diseases like ulcerative colitis, multiple sclerosis, and Crohn's disease. Researchers will identify which T-cells are active in inflamed tissues and find their targets. The goal is to discover new targe…

This study looks at different types of low back pain in 200 adults with ankylosing spondylitis. Researchers want to see how these pain types affect daily function and quality of life. Participants will fill out questionnaires during one visit. The goal is to better understand pai…