ANKYLOSING SPONDYLITIS

This early-stage trial tests a new stem cell treatment (HS_SW01) for people with ankylosing spondylitis, a condition that causes spine inflammation and stiffness. The study will enroll 18 adults aged 18 to 65 to check if the treatment is safe and helps reduce symptoms. Participan…

This study tests a new drug called vilamakitug for people with active axial spondyloarthritis, a type of inflammatory arthritis that causes back pain and stiffness. About 150 adults aged 18 to 65 with moderate to severe symptoms will receive either the drug or a placebo. The goal…

This study looks at whether people with rheumatic diseases (like rheumatoid arthritis or ankylosing spondylitis) have higher levels of harmful molecules called AGEs compared to healthy people. AGEs build up over time and can cause inflammation. Researchers will use a non-invasive…

This study will check if a protein called Tim-3 on certain white blood cells (neutrophils) can help doctors measure how active ankylosing spondylitis is in a patient. Researchers will compare Tim-3 levels with standard inflammation markers and MRI scans of the spine and hips. The…

This study will use a high-tech blood test (mass spectrometry) to look at different immune cells in 500 people with various autoimmune diseases and healthy volunteers. The goal is to find patterns that could help doctors screen for and diagnose these conditions earlier. No new tr…

This observational study will measure levels of certain immune proteins (IL-17, IL-38, IL-41) and a gene (HLA-B27) in 84 people with ankylosing spondylitis and healthy volunteers. The goal is to see if these markers are linked to disease activity and severity. No treatment is giv…