ANKYLOSING SPONDYLITIS

This study explores whether fecal transplants (capsules containing healthy donor stool) can improve quality of life and control inflammation in people newly diagnosed with rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, Crohn's disease, or ulcerative colitis. T…

This study looks at how well secukinumab works for people with active ankylosing spondylitis who have never taken certain biologic drugs before. Researchers will track changes in disease activity and inflammation over time. The goal is to see if this treatment helps control sympt…

This study tests a new drug called 608 for people with active ankylosing spondylitis, a type of arthritis that causes back pain and stiffness. About 500 adults who did not get enough relief from standard pain relievers will receive either 608 or a placebo. The main goal is to see…

This study tests a new drug called LNK01001 for people with active ankylosing spondylitis, a type of arthritis that causes back pain and stiffness. About 352 adults who haven't gotten enough relief from standard anti-inflammatory drugs will receive either LNK01001 or a placebo fo…

This study looks at whether a gluten-free diet can reduce inflammation and improve quality of life in people with ankylosing spondylitis, a type of arthritis that affects the spine. Researchers will compare a gluten-free diet to a regular diet over 8 weeks in 60 adults. The goal …

This study tests a new, ultrasound-guided acupotomy method to reduce pain and stiffness in people with ankylosing spondylitis. Researchers will compare the new technique to standard care in 60 adults with active disease. The goal is to see if this approach safely improves daily f…

This study is building a large database and sample bank from 5,000 adults with various rheumatic diseases like rheumatoid arthritis, lupus, and psoriatic arthritis. Researchers will use this information to find links between patient outcomes and biological markers. The goal is to…

This study is testing a new educational tool designed for people with melanoma who also have an autoimmune disease (like rheumatoid arthritis or Crohn's disease) and may receive immune checkpoint inhibitor drugs. Researchers want to see if the tool is easy to use and helpful for …

This study aims to collect information on how well shoulder replacements work over the long term, following up to 20,000 people for at least 10 years. Participants have various shoulder problems like arthritis, rotator cuff tears, or fractures. The goal is to better understand th…

This study collects tissue and blood samples from 300 people with autoimmune diseases like Crohn's, multiple sclerosis, and celiac disease. Researchers will look for T cells that are active in inflamed tissues to find their targets. The goal is to discover new targets for future …

This study looks at different types of low back pain in 200 adults with ankylosing spondylitis. Researchers want to see how these pain types affect daily function and quality of life. Participants will fill out questionnaires during one visit. The goal is to better understand pai…