Could ditching gluten ease ankylosing spondylitis?

NCT ID NCT07166874

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looks at whether an 8-week gluten-free diet can reduce gut inflammation and improve symptoms in people with ankylosing spondylitis. Researchers will measure changes in intestinal permeability, disease activity, and quality of life in 60 adults. Participants are randomly assigned to either a gluten-free diet or a placebo diet.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
gluten-free diet
What this could lead to
If it works, this could point toward a simple dietary change to help manage symptoms and gut health in ankylosing spondylitis.
What could go wrong
This is a small, early-stage trial with only 60 participants. The diet is short-term (8 weeks), and results may not apply to everyone. It's not a cure, and sticking to a gluten-free diet can be challenging.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bakırköy Dr. Sadi Konuk Training and Research hospital

    RECRUITING

    Istanbul, Turkey (Türkiye)

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Marmara University

    ACTIVE_NOT_RECRUITING

    Istanbul, Turkey (Türkiye)

  • İstanbul Medeniyet University

    ACTIVE_NOT_RECRUITING

    Istanbul, Turkey (Türkiye)

  • İstanbul Sağlık Bilimleri University

    ACTIVE_NOT_RECRUITING

    Istanbul, Turkey (Türkiye)

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