ANKYLOSING SPONDYLITIS

This study looked at whether taking NSAIDs every day, instead of only when needed, can prevent spine damage in people with ankylosing spondylitis who are also receiving anti-TNF therapy. 188 adults participated in this Phase 3 trial. The goal was to see if continuous NSAID use re…

This study looked at whether adding methotrexate to adalimumab (a biologic drug) reduces the chance that the body makes antibodies against adalimumab in people with ankylosing spondylitis. About 110 adults with active disease who did not respond well to NSAIDs took part. The goal…

This Phase 3 trial tested a new drug called XKH004 in 323 adults with moderate-to-severe active ankylosing spondylitis, a type of arthritis that causes back pain and stiffness. The drug works by blocking two inflammatory proteins, IL-17A and IL-17F. Participants received either X…

This study tested a drug called AK111 in 510 adults with active ankylosing spondylitis, a type of arthritis that causes back pain and stiffness. Participants received either AK111 or a placebo as a shot under the skin over 48 weeks. The main goal was to see if AK111 improves symp…

This study tested the drug RINVOQ in 69 adults with ankylosing spondylitis, a type of arthritis that mainly affects the spine. Participants took RINVOQ as prescribed by their doctor and were followed for up to a year. The goal was to see how safe and effective the drug is in real…

This study tested a drug called bimekizumab in 332 adults with active ankylosing spondylitis, a type of arthritis that causes back pain and stiffness. Participants received either the drug or a placebo injection. The goal was to see if the drug could reduce symptoms like pain and…

This study tested a new drug, netakimab, in 113 Chinese adults with active ankylosing spondylitis, a type of arthritis that causes back pain and stiffness. The goal was to see if netakimab works better than a placebo (a dummy treatment) at reducing symptoms. Participants received…

This Phase 3 trial tested golimumab, an anti-inflammatory biologic, given as an IV infusion to 208 people with active ankylosing spondylitis. Participants received either golimumab or a placebo. The main goal was to see if more people on golimumab had at least a 20% improvement i…

This study involved 324 adults with conditions like Crohn's disease, arthritis, or psoriasis who switched from a standard to a higher-concentration form of adalimumab (AVT-02). Researchers measured injection site pain and how well patients stuck with their treatment over 180 days…

This study tested whether wet cupping therapy, an ancient practice where small cuts are made on the skin and cups are used to draw out a small amount of blood, can help people with ankylosing spondylitis, a type of arthritis that mainly affects the spine. Half of the 100 particip…

This study tested whether kinesiology tape, applied to the back and shoulders, can reduce pain and improve posture, balance, and breathing in people with ankylosing spondylitis. 63 adults with the condition took part. The tape was compared with routine home exercises to see if it…

This study tested whether a 9-week personalized physical training program using an exercise bike could help people with ankylosing spondylitis, a type of arthritis that affects the spine. Fifty-six patients participated, and researchers measured how many achieved a meaningful imp…

This study tested whether wearable motion sensors can accurately measure spinal movement in people with ankylosing spondylitis (AS), a condition that causes back pain and stiffness. Forty participants (20 with AS and 20 healthy volunteers) wore sensors while performing everyday m…

This completed study looked at how the COVID-19 pandemic and social distancing impacted the mental health of 259 adults with chronic inflammatory rheumatism (like rheumatoid arthritis or ankylosing spondylitis). Researchers used questionnaires to measure stress, depression, anxie…

This completed study investigated whether air pollution affects flare-ups in people with rheumatoid arthritis, ankylosing spondylitis, or psoriatic arthritis. Researchers followed 86 patients for 6 months, asking them to complete weekly questionnaires about their symptoms. They a…

This completed study looked at nearly 7,000 adults with inflammatory joint diseases like rheumatoid arthritis and psoriatic arthritis. Researchers compared two versions of a standard health survey (EQ-5D-3L and EQ-5D-5L) to see which one better measures health and quality of life…

This study looks at whether CT scans are better than regular X-rays for measuring how the spine stiffens and fuses in people with ankylosing spondylitis. Researchers will follow 63 adults over 4 years, using scans, blood tests, and flexibility measurements. The goal is to find a …

This completed study examined the link between erectile dysfunction, nerve pain, disease activity, and daily function in 90 men with axial spondyloarthritis (a type of arthritis affecting the spine). Participants were either on anti-TNF drugs, NSAIDs, or were healthy volunteers. …

This study used MRI to examine neck muscles in 158 people with ankylosing spondylitis (AS), a type of arthritis that affects the spine. Researchers measured muscle size, fat buildup, and spine alignment, comparing them to healthy controls. The goal was to better understand how AS…

This study tested whether a non-invasive ultrasound device can reduce inflammation in people with inflammatory arthritis (psoriatic arthritis, rheumatoid arthritis, or ankylosing spondylitis). Sixteen participants received four sessions of focused ultrasound or a sham (placebo) t…

This study looks at how genes might influence the severity of ankylosing spondylitis, a type of arthritis that can fuse spine bones. Researchers will follow 299 adults with the condition for up to 5 years, tracking symptoms, spine flexibility, and X-rays. The goal is to identify …

This study looked at how a special exercise approach called BETY affects people with rheumatic diseases (like arthritis) who have chronic pain. Researchers reviewed past records of 300 participants to see if BETY improved their physical function, mood, and quality of life compare…

This completed study followed 127 adults with moderate to severe plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, or non-radiographic axial spondyloarthritis who were already taking or starting secukinumab. Researchers observed them for two years to see how long the…