Gene hunt for spine arthritis severity begins
NCT ID NCT00056719
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how genes might influence the severity of ankylosing spondylitis, a type of arthritis that can fuse spine bones. Researchers will follow 299 adults with the condition for up to 5 years, tracking symptoms, spine flexibility, and X-rays. The goal is to identify genetic factors linked to worse disease, which could help predict outcomes in the future.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help identify genetic markers that predict disease severity, potentially guiding personalized treatment approaches.
- What could go wrong
- This is an observational study, not a treatment trial. It may not find clear genetic links, and results may not lead to immediate clinical changes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
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