Gene hunt for spine arthritis severity begins
NCT ID NCT00056719
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how genes might influence the severity of ankylosing spondylitis, a type of arthritis that can fuse spine bones. Researchers will follow 299 adults with the condition for up to 5 years, tracking symptoms, spine flexibility, and X-rays. The goal is to identify genetic factors linked to worse disease, which could help predict outcomes in the future.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help identify genetic markers that predict disease severity, potentially guiding personalized treatment approaches.
What could go wrong
This is an observational study, not a treatment trial. It may not find clear genetic links, and results may not lead to immediate clinical changes.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States