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Chemical peels show promise for acne and dark spots in new study

NCT ID NCT07240051

Disease control Sponsor: Nahla Maher Mahmoud Mahran Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested three types of chemical peels—50% glycolic acid, 30% salicylic acid, and modified Jessner's—on 90 adults with mild to moderate facial acne and post-acne dark spots. Participants received one type of peel, and doctors measured improvements in acne severity and pigmentation. The goal was to see which peel works best and is safest for treating both active breakouts and leftover marks.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
chemical peels (50% glycolic acid, 30% salicylic acid, modified Jessner's solution)
What this could lead to
If effective, these peels could offer a safe, affordable option to reduce acne and dark spots without long-term medication.
What could go wrong
This is a small, completed trial with no blinding or long-term follow-up. Results may not apply to all skin types or severe acne. Risks include irritation, redness, and scarring.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

90 people

The number who actually took part.

Started

Mar 2024

Finished

Jul 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Up to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Facial active acne (mild and moderate cases) * post-acne hyperpigmentation * a minimum age of 18 years * skin phototype III or IV Exclusion Criteria: * Pregnant or nursing women * active infection in the treatment area (e.g., verrucae and herpes simplex) * systemic disease (hypertension, diabetes, or bleeding tendency) * systemic retinoid or laser treatment within the last 6 months * history of keloidal tendency or Aspirin sensitivity.

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Conditions

The condition(s) this trial relates to.

acne Acne Vulgaris

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acne Peeling

Contacts and locations

Locations

  • Cairo University

    Cairo, 13114, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.