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Eyelid wipes zap Mite-Caused eye inflammation in new study

NCT ID NCT07451678

Disease control Sponsor: Instituto de Oftalmología Fundación Conde de Valenciana Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 09, 2026 · Updated 2 times

Summary

This study tested whether cleaning the eyelids with wipes containing chlorhexidine can treat blepharitis caused by Demodex mites. 106 adults with the condition used the wipes twice daily for four weeks. Researchers measured mite counts and eyelash debris before and after treatment to see if the wipes reduced the infection and symptoms.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

39 people

The number who actually took part.

Started

Jul 2024

Finished

Jan 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 years * Clinical diagnosis of Demodex folliculorum blepharitis * Presence of eyelash collarettes on slit-lamp examination * Positive identification of Demodex folliculorum by epilation of 4 upper and 4 lower eyelashes per eyelid and visualization under light microscopy * Willingness to use chlorhexidine eyelid wipes as instructed for 8 weeks Exclusion Criteria: * Use of topical or systemic antiparasitic treatment within the past 6 weeks * Use of topical ophthalmic antibiotics or anti-inflammatory medication within the past 6 weeks * Known allergy or hypersensitivity to chlorhexidine * Pregnancy or breastfeeding

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Conditions

The condition(s) this trial relates to.

blepharitis Demodex folliculitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Blepharitis

Contacts and locations

Locations

  • Instituto de Oftalmologia F.A.P. Conde de Valenciana, I.A.P.

    Mexico City, Mexico City, 06800, Mexico

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