A new serum aims to clear acne and boost skin confidence
NCT ID NCT07752368
First seen Aug 07, 2026 · Last updated Aug 07, 2026
Summary
This trial tests a topical serum containing 0.5% salicylic acid in adults with acne-prone skin. Over eight weeks, participants apply the serum as directed and report changes in acne symptoms, skin texture, tone, and more. The study uses questionnaires and expert photo grading to see if the serum makes a visible difference.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- A topical serum containing 0.5% salicylic acid
- What this could lead to
- If successful, this serum could offer a simple, over-the-counter option to ease acne symptoms and improve skin appearance and quality of life.
- What could go wrong
- This is a small, early-stage study without a placebo group, so results may not prove the serum works better than no treatment. Individual results can vary, and the serum may not work for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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25 people
The number who actually took part.
- Started
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Jun 2023
- Finished
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Aug 2023
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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24 to 47 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male or female between the ages of 24-47 (between 2-4 males, the remainder females) * Actively has acne (non-inflamed and/or inflamed acne) * Has previously used or is currently using exfoliating acids (AHAs / BHA) and is willing to stop this for the duration of the study * Has not experienced sunburn on the face in the last month * No open wounds, sores, or non-acne related lesions on the face * Generally healthy - don't live with any uncontrolled chronic disease * Willing to apply SPF on a daily basis during the study and to use other sun protection on the face (i.e. a hat) * Must be willing to avoid products with coconut oil and shea butter, and Ethylhexyl Palmitate for the duration of the study * Must be willing to cut out whey protein and cow's milk from their diet for the duration of the study * Must be willing to avoid biotin products or supplements for the duration of the study * Must agree to avoid sun tanning, tanning beds, and self-tanning products for the duration of the study Exclusion Criteria: * Any pre-existing chronic conditions that would prevent participants from adhering to the protocol, including oncological and psychiatric disorders * Anyone with known severe allergic reactions * Women who are pregnant, breastfeeding or attempting to become pregnant * Unwilling to follow the study protocol * Smoker * Anyone consuming products containing Tetrahydrocannabinol (THC) * Identifies as a person with sensitive skin * Anyone currently on steroids or undergoing hormone replacement therapy * Anyone using prescription medication relevant to the skin * Undergoing any cosmetic procedures during the study including facials, Botox, dermal filler, laser, or chemical peel treatments * Use of prescription drug (topical or oral) that is targeted at any sort of skin condition (e.g., retinoids, accutane) * Anyone allergic to niacinamide or salicylic acid * Anyone who regularly consumes biotin supplements and is unwilling to stop for the duration of the study * Participants who stopped using birth control within the past 3 months * Participants currently have a Copper IUD or are using one of the following birth control high in androgen and low in estrogen activity: Amethyst, Jolessa, Lessina, Levonest/Levora, Lutera, Nordette, Portia, Seasonale/Seasonique, Sronyx, Mirena IUD, Triphasil/Trivora, Cryselle, Lo-Ovral/Ovral, Low-Ogestrel/Ogestrel, Lo-Feminol, Ortho tricyclen Lo, Estrostep Fe, Loestrin, Microgestin, Apri, Mircette, Azurette, Caziant, Cyclessa, Desogen, Emoquette, Kariva, Linessa, Marvelon, NuvaRing, Depo-Provera, Reclipsen
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Citruslabs
Las Vegas, Nevada, 89101, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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