Acne

This study tests an mRNA vaccine designed to fight acne. Researchers will give two shots to 120 adults aged 18 to 45 with mild acne. The goal is to see if the vaccine is safe and reduces pimples. Participants are randomly assigned to receive the vaccine or a placebo.

This trial tests whether a radiofrequency device can reduce inflammatory acne lesions as effectively as a standard topical gel. About 60 adults with mild-to-moderate facial acne will be randomly assigned to receive either three radiofrequency sessions or daily application of a co…

This study tests an experimental mRNA vaccine designed to treat moderate to severe acne in adults aged 18 to 45. The vaccine is given as up to three injections into the muscle. Researchers will monitor safety, immune response, and how well it reduces acne lesions. The trial invol…

This study is testing a gel called CABTREO, which combines three acne-fighting ingredients (clindamycin, adapalene, and benzoyl peroxide), in children aged 9 to 11 with moderate to severe acne. The goal is to see if it is safe and works well over 12 weeks. About 100 kids will app…

This study compares giving oral isotretinoin (a strong acne medication) right away versus the usual antibiotics for moderate acne in people with darker skin (Fitzpatrick types IV-VI). The goal is to see if early use of isotretinoin reduces acne-related dark spots better than stan…

This study compares a weekly dose of isotretinoin (a vitamin A derivative) to daily tetracycline antibiotics for treating moderate acne. Researchers want to see if the weekly approach works just as well, with fewer side effects and less reliance on antibiotics. The trial will enr…

This study tests a cream made from a common probiotic, Lactobacillus reuteri, that has been coated with a special material to help it survive on the skin. The goal is to see if it can rebalance the skin's bacteria and reduce acne. About 196 people with mild to moderate acne will …

This study tests whether cold atmospheric plasma (CAP) can safely and effectively treat moderate-to-severe acne. 220 adults aged 18-40 will receive either CAP or a placebo treatment once a week for six weeks. The goal is to see if CAP reduces acne lesions better than placebo, off…

Researchers at Sohag University Hospital want to know how many women with acne also have polyendocrine metabolic ovarian syndrome, a hormonal and metabolic condition. The study enrolls 90 women aged 15 to 49 who have been diagnosed with acne. Doctors will check each participant f…

Researchers are testing a 1550nm non-ablative fractional laser on adults with skin concerns such as acne scars, wrinkles, and dark spots. The trial enrolls about 200 people aged 18 to 70. Participants receive laser treatment, then answer questionnaires about their experience. Der…

This study tests a 4-week skincare routine made with coconut oil to see if it safely and effectively manages mild to moderate acne in people with sensitive skin. Participants will use a cleanser, toner, serum, and day cream, with skin assessments at the start and end of the trial…

This early-stage trial tests an experimental oral drug called TVB-3567 in 128 healthy adults, some with acne. The main goal is to check safety and how the body processes the drug, not yet whether it works. Results will help decide if larger studies are warranted.

This study tests whether a daily probiotic drink can improve immune function and reduce skin inflammation in women aged 40-60 going through menopause. Participants will drink either a probiotic or a plain milk drink for 8 weeks. Researchers will measure immune aging, inflammation…

This study tests if timolol eye drops, applied as a cream, can reduce the red marks left after acne. It compares the drops to intense pulsed light (IPL) therapy in 60 people aged 12 and older. The goal is to see if a simple, low-cost option can work as well as a laser treatment.

Researchers at Biruni University are studying whether baseline blood levels of three hormones (DHEAS, FSH, and LH) are linked to how well adult women with moderate to severe acne respond to the drug isotretinoin. The trial enrolls 64 women aged 18 and older who are starting syste…

This study looks at how two common acne antibiotics, sarecycline and doxycycline, change the bacteria living in your gut and on your skin. Researchers will track these changes in 30 people with acne over the treatment period. The goal is to understand which antibiotic is gentler …

This study is creating a group of 200 acne patients at Nantes University Hospital to learn more about the disease. Researchers will track factors like acne severity, quality of life, and treatment costs, and collect skin samples. The goal is to better understand what makes acne w…

This study collects skin samples from 500 people with conditions like acne, eczema, and psoriasis, as well as healthy volunteers. Researchers will analyze the samples to find biomarkers and gene patterns linked to inflammation. The goal is to better understand these skin diseases…