Nano-Silver bandage promises quicker gum recovery after dark spot removal
NCT ID NCT07521176
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested whether a nano-crystalline silver dressing helps gums heal faster and with less pain after surgical removal of dark gum pigmentation. Twelve adults with moderate to severe gum pigmentation had the surgery, and the silver dressing was compared to a standard dressing. The researchers measured wound healing, skin regrowth, and pain levels over four weeks.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- nano-crystalline silver membrane
- What this could lead to
- If it works, this could offer a better way to heal gums after cosmetic surgery, with less pain and faster recovery.
- What could go wrong
- This was a very small study with only 12 people, so results may not apply to everyone. The treatment is for healing after a cosmetic procedure, not for a serious disease.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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12 people
The number who actually took part.
- Started
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Jun 2024
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 40 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Gingival Hyperpigmentation: Presence of physiological melanin pigmentation in the maxillary anterior region, categorized as Grade 3 or 4 according to the Heden Gingival Pigmentation Index. 2. Age Demographic: Patients aged 20 years or older. 3. Periodontal Health: Absence of active periodontal disease (e.g., periodontitis or gingivitis). 4. Gingival Biotype: Presence of a medium-to-thick gingival biotype. 5. Attached Gingiva: An adequate width of attached gingiva to ensure surgical stability. 6. Oral Hygiene: Demonstration of good oral hygiene with a proven ability to maintain effective plaque control throughout the study period. Exclusion Criteria: 1. Systemic Pigmentation: Presence of gingival discoloration secondary to systemic conditions or metabolic disorders. 2. Drug-Induced Pigmentation: Hyperpigmentation resulting from the administration of specific pharmacological agents. 3. Poor Oral Hygiene: Inadequate plaque control or a lack of compliance with oral self-care instructions. 4. Smoking Status: Current smokers or individuals with a recent history of tobacco use, due to its confounding effect on gingival pigmentation and wound healing. 5. Physiological Status: Pregnant or lactating women. 6. Systemic Health \& Medication: Patients with underlying systemic diseases or those receiving medications known to influence periodontal tissue integrity or inflammatory response (e.g., immunosuppressants or calcium channel blockers). 7. Periodontal Disease: Presence of active periodontitis or attachment loss.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Damascus University, Faculty of Dentistry, Department of periodontology.
Damascus, Syria
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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