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Nano-Silver bandage promises quicker gum recovery after dark spot removal

NCT ID NCT07521176

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested whether a nano-crystalline silver dressing helps gums heal faster and with less pain after surgical removal of dark gum pigmentation. Twelve adults with moderate to severe gum pigmentation had the surgery, and the silver dressing was compared to a standard dressing. The researchers measured wound healing, skin regrowth, and pain levels over four weeks.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
nano-crystalline silver membrane
What this could lead to
If it works, this could offer a better way to heal gums after cosmetic surgery, with less pain and faster recovery.
What could go wrong
This was a very small study with only 12 people, so results may not apply to everyone. The treatment is for healing after a cosmetic procedure, not for a serious disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

12 people

The number who actually took part.

Started

Jun 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Gingival Hyperpigmentation: Presence of physiological melanin pigmentation in the maxillary anterior region, categorized as Grade 3 or 4 according to the Heden Gingival Pigmentation Index. 2. Age Demographic: Patients aged 20 years or older. 3. Periodontal Health: Absence of active periodontal disease (e.g., periodontitis or gingivitis). 4. Gingival Biotype: Presence of a medium-to-thick gingival biotype. 5. Attached Gingiva: An adequate width of attached gingiva to ensure surgical stability. 6. Oral Hygiene: Demonstration of good oral hygiene with a proven ability to maintain effective plaque control throughout the study period. Exclusion Criteria: 1. Systemic Pigmentation: Presence of gingival discoloration secondary to systemic conditions or metabolic disorders. 2. Drug-Induced Pigmentation: Hyperpigmentation resulting from the administration of specific pharmacological agents. 3. Poor Oral Hygiene: Inadequate plaque control or a lack of compliance with oral self-care instructions. 4. Smoking Status: Current smokers or individuals with a recent history of tobacco use, due to its confounding effect on gingival pigmentation and wound healing. 5. Physiological Status: Pregnant or lactating women. 6. Systemic Health \& Medication: Patients with underlying systemic diseases or those receiving medications known to influence periodontal tissue integrity or inflammatory response (e.g., immunosuppressants or calcium channel blockers). 7. Periodontal Disease: Presence of active periodontitis or attachment loss.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Damascus University, Faculty of Dentistry, Department of periodontology.

    Damascus, Syria

More trials for these conditions

Other studies related to the condition(s) this trial covers.