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Honey vs. steroids: can a sweet paste soothe chronic mouth pain?

NCT ID NCT06988527

Disease control Sponsor: Dar Al Uloom University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Aug 28, 2026 · Updated 3 times

Summary

This study tests a honey-based paste against a standard steroid ointment for treating painful mouth sores caused by oral lichen planus. Fifty-six adults with erosive or atrophic lichen planus will use the paste daily for four months. Researchers will track symptom improvement, pain levels, and quality of life to see if honey can be a gentler alternative.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
honey in orabase (1:1) paste
What this could lead to
If it works, this could offer a natural, low-cost alternative to steroid treatment for managing oral lichen planus symptoms.
What could go wrong
This is a small, early-phase study (56 participants) comparing honey to a standard steroid. Honey may not be as effective, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

56 people

The number who actually took part.

Started

May 2025

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

35 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with a clinical diagnosis of oral lichen planus * Symptomatic OLP lesions (erosive/atrophic) * Participants are between 35 and 60 years old, who are able to adhere to the study protocol, and sign informed consent. Exclusion Criteria: * Patients with other oral mucosal disorders, or systemic conditions influencing OLP or wound healing, allergies or hypersensitivity to honey or triamcinolone * Patients who administer systemic corticosteroids or immunosuppressive agents. * Pregnancy or lactation * Inability to comprehend or adhere to study directives * Patients who are not able to sign an informed written consent

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Conditions

The condition(s) this trial relates to.

atrophic lichen planus lichen planus, oral oral erosive lichen

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atrophic lichen planus Erosive oral lichen planus

Contacts and locations

Locations

  • Dar AlUloom University

    Riyadh, 11512, Saudi Arabia

More trials for these conditions

Other studies related to the condition(s) this trial covers.