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Light therapy vs. steroids: which saves your taste buds?
NCT ID NCT07536737
First seen Jun 27, 2026 · Last updated Jul 15, 2026 · Updated 2 times
Summary
This study looked at two treatments for oral lichen planus, a chronic mouth condition that can cause pain and change how food tastes. Researchers compared a light-based treatment (photodynamic therapy) with steroid cream in 65 adults. They measured taste ability, pain, and lesion size before and after treatment to see which approach works better for improving symptoms.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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65 people
The number who actually took part.
- Started
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Sep 2021
- Finished
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Jul 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * age 18 years or older * clinically and histologically confirmed diagnosis of oral lichen planus Exclusion Criteria: * pregnancy or lactation presence of systemic diseases, including dermatologic diseases, oncologic diseases, or severe liver disorders known allergies use of immunomodulatory or immunosuppressive drugs use of antidepressants use of bone anti-metabolites photosensitivity allergy to the components of the photosensitizer treatment for oral lichen planus within the previous 6 months inability to attend follow-up visits presence of oral lesions other than oral lichen planus
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Medical University of Bialystok
Bialystok, Podlaskie Voivodeship, 15-089, Poland
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Aloe vera vs. steroid: which tames oral lichen planus?
- Can a common steroid gel quiet oral lichen planus by altering MicroRNAs?
- A pharmacist in the dentist's chair: could a new team approach tame stubborn mouth conditions?
- New oral spray aims to ease sore throat and canker sores without drugs
- Gum disease link in mouth condition under investigation