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Can repeated weight loss and gain harm Athletes' metabolism?

NCT ID NCT04107545

Knowledge-focused Sponsor: University Hospital, Clermont-Ferrand Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This study looks at how athletes who regularly lose and regain weight to meet competition categories experience changes in metabolism, body temperature, and body composition. Researchers will track 48 athletes through periods of weight maintenance, loss, and regain, using body temperature monitors and body scans. The goal is to understand the long-term health impacts of weight cycling and find ways to protect athletes from potential metabolic issues.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Behavioral intervention: monitoring body temperature and body composition during weight cycling phases
What this could lead to
If successful, this could reveal how repeated weight cycling affects athletes' metabolism and health, potentially guiding safer weight management strategies.
What could go wrong
This is an observational study with a small sample size, so findings may not apply to all athletes. It does not test a treatment, so direct health benefits are uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

48 people

The number who actually took part.

Started

May 2021

Finished

Dec 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Subjects aged 18 to 35 (inclusive), * exercising at least 4 sessions of endurance or weight-based sporting activities per week for a performance objective, * having variations of at least 5% of their weight body during the last 3 sporting seasons (a sporting season corresponds to a year during which alternates the periods of training, recovery and participation in official competitions). * Subject capable of providing informed consent to participate * Subject with a social security insurance. Exclusion Criteria: * Medical or surgical history deemed by the investigator to be incompatible with the study. * Presence of chronic pathology. * Disorders of eating behavior. * Subjects born very prematurely defined as a pregnancy inferior to 28 weeks. * Subjects having used a treatment for a small stature (eg growth hormone). * For women: irregular menstruation (changes in menstrual cycles ≥ 6 days). * Sports subjects with a stable weight during the last three sporting seasons (weight variation \<5%). * Take medication that can change body temperature. * Pregnant or lactating women. * Subjects with gastrointestinal complications and / or contraindications to ingestion of the capsule (eg diverticulosis, inflammatory bowel disease, gastrointestinal surgery ...). * Subjects needing MRI during ingestion of the capsule or having a pacemaker or other implanted electro-medical device. * Person under guardianship or not subject to a social security scheme. * Refusal to sign the information and consent leaflet. * Refusal of participation

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Conditions

The condition(s) this trial relates to.

tinea pedis Weight Cycling

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Athletes

Contacts and locations

Locations

  • Chu Clermont Ferrand

    Clermont-Ferrand, 63003, France

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