Female reproductive organ cancer

This phase 1 trial is testing an experimental therapeutic cancer vaccine called AST-021p in people with advanced solid tumors that no longer respond to standard treatments. The goal is to see if the vaccine is safe and can trigger an immune response against the cancer. Participan…

This early-stage study tested a vaccine called DCP-001 in 17 women with a serious type of ovarian cancer who had already completed standard treatment. The goal was to see if the vaccine is safe and can boost the immune system to recognize and fight cancer cells. Researchers measu…

This study looked at whether a special care plan led by a geriatrician and a nurse could improve survival and quality of life for older adults (70+) with advanced cancer. 792 patients with breast, colorectal, lung, prostate, bladder, ovarian cancer, or lymphoma took part. The app…

This study tested two treatments for people with advanced cancer who cannot have standard therapy. One group took a low-dose chemotherapy pill (cyclophosphamide) daily, and the other took a hormone pill (megestrol). The goal was to see which treatment could slow cancer growth for…

This phase 2 study tested the drug erdafitinib in 316 adults and children with advanced solid tumors that have specific FGFR gene mutations or fusions. The main goal was to see if the drug could shrink tumors. Participants took erdafitinib tablets daily. The study is now complete…

Researchers are testing a radiation technique called PULSAR in people with metastatic cervical cancer. PULSAR delivers radiation in short bursts to pelvic tumors, guided by imaging, alongside standard systemic therapy. The trial aims to see whether this approach improves overall …

This early-phase trial tested a new drug called TdCyd in 27 adults with advanced solid tumors that had stopped responding to standard treatments. The drug is designed to turn back on genes that may slow tumor growth. The main goal was to find a safe dose and check for side effect…

This early-phase trial tested whether adding nilotinib (a pill) to paclitaxel (a chemotherapy) is safe and tolerable for people with advanced solid tumors that no longer respond to standard treatments. The study included 47 adults and children aged 12 and older. Researchers aimed…

This early-phase trial tested a combination of two chemotherapy drugs (gemcitabine and carboplatin) plus lenalidomide, a drug that blocks blood vessel growth in tumors, in 18 adults with advanced solid tumors, especially urothelial (bladder) cancer. The main goal was to find the …

This phase II trial is testing an oral drug called giredestrant in 30 people with grade 1 endometrial cancer. The goal is to see if the drug can shrink or control the cancer over 6 months. Participants take one pill daily for up to 24 cycles, and doctors monitor tumor changes and…

This early-phase trial tests a new drug called AI-061, which combines two immune-boosting antibodies (anti-PD-1 and anti-CTLA-4) into one treatment. The study will enroll 18 adults with advanced solid tumors that have spread or cannot be removed. The main goals are to find a safe…

This Phase 2 trial tests two experimental drug combinations in 63 women with a specific type of ovarian cancer (BRCA-mutant or HRD-positive) that has worsened after prior PARP inhibitor treatment. Participants receive either tuvusertib plus niraparib or tuvusertib plus larteserti…

This early-stage trial is testing a new drug called tuvusertib, given together with either lartesertib or avelumab, in people with advanced solid tumors that have not responded to standard treatments. The main goals are to check safety, find the best dose, and see how the body pr…

This early-phase trial tested a new drug called vilastobart, alone or with another drug (atezolizumab), in 125 people with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check safety and find the right dose. Researchers also looke…

This phase 1 trial is testing whether a diet that severely limits arginine—an amino acid some tumors depend on—is safe and might help control solid tumors. About 25 adults with solid tumors will follow a specially designed low-arginine liquid diet for two 3-week cycles while cont…

This early-phase trial tests a new drug, SG1827, in people with advanced solid tumors that have stopped responding to standard treatments or have no standard therapy available. The main goals are to check the drug's safety, find the best dose, and get a first look at whether it c…

This early-stage trial tests an experimental drug called SG2918 in 17 people with advanced cancers that no longer respond to standard treatments. The main goal is to check safety and find the right dose, not yet to prove it works. Participants receive the drug by IV every three w…

This study tested three flavors of Supportan® drink (Tropical Fruits, Cappuccino, and Pineapple-Coconut) in 123 cancer patients undergoing chemotherapy, radiotherapy, immunotherapy, or targeted therapy. Patients drank two bottles daily for four weeks alongside their normal diet. …

This trial tests an experimental drug called FLX475, given alone or with the immunotherapy pembrolizumab, in people with advanced cancers that have not responded to standard treatments. The study aims to find the safest dose and to see whether the combination can shrink tumors. P…

This study looks at whether eating a high-fiber diet (over 21 grams per day) can change gut bacteria and improve the immune system's ability to fight solid tumors like colorectal cancer. About 25 adults with solid tumors will follow this diet to see if it is safe and helps with t…

This trial tests an experimental drug called SNS-101, which targets a protein called VISTA that may help tumors evade the immune system. Researchers give SNS-101 alone or with another immunotherapy, cemiplimab, to adults with advanced solid tumors that have not responded to stand…

This trial tests whether giving a higher radiation dose during brachytherapy, a type of internal radiation, can improve local control in patients with locally advanced cervical cancer. Participants receive standard external beam radiation and chemotherapy, plus a boosted brachyth…

This trial tests a structured diet and exercise program for overweight Chinese cancer survivors. The program, led by a dietitian and a cancer exercise specialist, teaches weight loss strategies, healthy eating, and physical activity. Researchers want to see if the program is prac…

This phase 1 trial tested the combination of dasatinib (a pill) and bevacizumab (an infusion) in 50 adults with advanced solid tumors that no longer respond to standard treatments. The goal was to find the safest dose and see how well the two drugs work together to slow cancer gr…

This phase 1 trial tests an experimental drug called MRG003 in people with advanced solid tumors, including colorectal cancer, head and neck squamous cell carcinoma, and nasopharyngeal carcinoma. The study aims to find a safe dose and to see whether the drug can shrink tumors. Pa…

This early-phase study tests an experimental drug called MK-6837, given alone or with another drug (pembrolizumab), in people with advanced solid tumors that have not responded to standard treatments. The main goals are to check safety, find the right dose, and see if the drug sh…

This early-phase trial tested a combination of two drugs, vandetanib and everolimus, in 151 people with advanced or metastatic cancer that had stopped responding to standard treatments. The goal was to find the safest dose and see if the combination could slow or stop cancer grow…

This trial is testing whether a new form of chemotherapy called PLX038 can be safely combined with the PARP inhibitor rucaparib to shrink tumors in people with small cell lung cancer, small cell cancer outside the lungs, or other solid tumors. The study has two parts: first, find…

This phase 2 trial tested the drug nirogacestat in 53 people with recurrent ovarian granulosa cell tumors, a rare type of ovarian cancer. The goal was to see if the drug could shrink tumors or slow the disease. Participants took nirogacestat orally, and researchers measured how m…

This phase 2 trial is investigating whether adding an experimental DNA-based therapy called ELENAGEN to the chemotherapy drug gemcitabine can help people with platinum-resistant ovarian cancer. The study will compare the combination against gemcitabine alone, measuring how long p…

This study looked at whether using an anti-cancer cream (5-fluorouracil) in the vagina after surgery is an acceptable and feasible way to treat cervical precancer in 180 South African women living with HIV. The goal was to see if women would stick with the treatment and find it a…

This early-stage trial is testing whether combining two chemotherapy drugs, temozolomide and topotecan, is safe and tolerable for children and adolescents with malignant tumors that have returned or not responded to standard treatments. The study aims to find the highest safe dos…

This trial investigates an experimental oral drug, LY3143921 hydrate, which blocks a protein called Cdc7 that cancer cells need to divide. It is being tested in adults with advanced solid tumours, including colorectal, ovarian, lung, and pancreatic cancers, that have not responde…

This trial is testing a procedure called HIPEC, where a heated chemotherapy drug (cisplatin) is delivered directly into the abdomen after surgery to remove visible cancer. The goal is to find the safest dose that can be used in patients with advanced ovarian, fallopian tube, or p…

This phase 1 trial is testing whether adding the antiviral drug Vistide (cidofovir) to the standard combination of radiation and chemotherapy can improve outcomes for people with HPV-positive cervical cancer. The idea is that Vistide may make cancer cells more sensitive to radiat…

This early-stage trial is testing whether combining two experimental immunotherapy drugs, zalifrelimab and balstilimab, can help shrink or control advanced solid tumors, including cervical cancer. The drugs are designed to block different 'brakes' on the immune system, potentiall…

This study looked at whether giving heated chemotherapy directly into the abdomen during a second-look surgery is possible for people with ovarian, fallopian tube, or peritoneal cancer. Ten participants who had already received standard treatment were enrolled. The goal was to se…

This early-stage trial is testing an investigational therapy called OH2, a modified herpes simplex virus designed to infect and destroy cancer cells while also stimulating the immune system. The study will evaluate OH2 alone or in combination with the immunotherapy drug pembroliz…

This early-stage trial is testing an experimental drug called AEB1102 in people with advanced solid tumors that have not responded to standard treatments or for which no standard treatment exists. The main goal is to find the highest dose that is safe and to understand the drug's…

This phase II trial is testing whether the chemotherapy drug eribulin, given alone or combined with the immunotherapy pembrolizumab, can help people with ovarian or uterine carcinosarcoma that has returned or progressed. The study aims to see if these treatments can shrink tumors…

This early-phase trial is testing an oral drug called ATRN-119 in 132 people with advanced solid tumors that have specific DNA repair mutations. The main goals are to check safety, how the drug moves through the body, and whether it can shrink tumors. Participants must be able to…

This phase 2 trial tests the drug cabozantinib in women with advanced or metastatic cervical cancer that has worsened after platinum-based chemotherapy. The study aims to see if cabozantinib can control the disease and how safe it is, particularly regarding risks like fistulas. P…

This trial tests whether giving the sedative dexmedetomidine during and after reconstructive microsurgery can help transplanted tissue (flaps) survive better in cancer patients. The study will compare flap health at 48 hours after surgery in patients receiving dexmedetomidine ver…

This phase 1 trial is testing an experimental drug called STP707 in people with advanced or metastatic solid tumors that have not responded to standard treatments. The study aims to find a safe dose and see whether the drug can slow or shrink tumors. Participants receive STP707 b…

This study tested a new radioactive drug, 177Lu-NeoB, in 35 adults with advanced solid tumors that have a specific marker (GRPR). The goal was to check safety, find the best dose, and see if it shrinks tumors. It is an early-stage trial, so it focuses on safety and dosing, not a …

This trial compares two common methods for placing a totally implantable vascular access device (TIVAD), a port used for chemotherapy and other treatments in cancer patients. Researchers are randomly assigning patients to have the port inserted via either the internal jugular vei…

This trial compares two ways to make the first incision for laparoscopic surgery in women with endometrial cancer: the standard umbilical entry versus entry through the Lee-Huang point, a spot on the upper left abdomen. The goal is to see which approach leads to fewer complicatio…

This trial tests an experimental drug, RSO-021, given directly into the chest cavity of people with malignant pleural effusion—a buildup of fluid around the lungs caused by advanced solid tumors or mesothelioma. The study aims to find a safe dose and check for early signs that th…

This phase 3 trial tests whether a web-based physical activity program, including a wearable tracker and interactive app, can improve fitness and long-term health in children and adolescents who have completed cancer treatment. Participants are randomly assigned to receive either…

This study monitors the safety and effectiveness of the drug olaparib (Lynparza) in people with ovarian, breast, prostate, or pancreatic cancer who are prescribed it as part of routine care in South Korea. Researchers will track side effects and how long the cancer stays under co…

This early-phase trial is testing an experimental drug called SM3321 in people with advanced solid tumors that have stopped responding to standard treatments. The main goal is to see if the drug is safe and tolerable, and to find the best dose. Participants receive SM3321 as a we…

This early-stage trial tests an experimental drug called JS015 in people with advanced solid tumors who have run out of standard treatment options. The main goal is to check the drug's safety, find the best dose, and see how the body processes it. Up to 12 participants will recei…

This study tests a support program that brings together oncologists, pharmacists, doctors, and nurses to help cancer patients take their oral medications as prescribed. The goal is to improve treatment effectiveness and patient safety by ensuring better communication and follow-u…

This phase II trial tests whether combining two hormone-blocking drugs — onapristone and anastrozole — can shrink tumors or slow cancer growth in women with hormone-receptor-positive endometrial cancer that has not responded to prior chemotherapy. Onapristone blocks progesterone …

This trial tests an experimental drug called enfortumab vedotin, which is designed to seek out and destroy cancer cells that have a specific protein called Nectin-4 on their surface. The study includes people with metastatic urothelial cancer (a type of bladder cancer) and other …

This early-stage trial tests an experimental drug called SHR-7367 in people with advanced solid tumors that have spread or cannot be removed by surgery. The main goals are to check the drug's safety, find the best dose, and see if it can shrink tumors. About 22 participants will …

This early-phase trial tests an experimental oral drug, MK-6598, both by itself and in combination with the immunotherapy pembrolizumab (Keytruda) in adults with advanced or metastatic solid tumors. The main goals are to check safety, find the right dose, and see early signs of t…

This early-phase trial tests a new drug called PEP-010 in people with advanced solid tumors that have spread. The study checks if PEP-010 is safe alone or with chemotherapy (paclitaxel or gemcitabine). About 57 adults with metastatic pancreatic, ovarian, or other solid cancers wi…

This early-phase trial tests an experimental drug called JS006, either by itself or combined with another drug (toripalimab), in people with advanced tumors who have no standard treatment options left. The goal is to see if the combination is safe and tolerable, and to find the b…

This study tests a new drug called pegilodecakin, a lab-made version of a natural immune protein (interleukin-10), in people with advanced solid tumors such as melanoma, lung, breast, prostate, ovarian, kidney, colorectal, and pancreatic cancers. The drug is given as a daily shot…

This early-phase study tests a new oral drug called TT125-802 in 50 adults with advanced solid tumors (like lung cancer) that have not responded to standard treatments. The main goals are to check the drug's safety, find the right dose, and see if it can shrink tumors. It is a fi…

This phase II trial investigates whether adding the immunotherapy drug pembrolizumab (Keytruda) to standard chemotherapy (carboplatin and paclitaxel) improves outcomes for people with advanced stage III-IV ovarian, fallopian tube, or primary peritoneal cancer. The study aims to s…

This early-stage trial is testing a combination of two lab-made antibodies in people with advanced solid tumors that have not responded to standard treatments. One antibody (LDP) aims to reactivate the immune system against cancer, while the other (CDP1) blocks a growth signal on…

This phase II trial tests whether the drug RAD001 can shrink or slow the growth of tumors in people with recurrent endometrial cancer. Participants take RAD001 daily by mouth. The study measures how many patients have their tumors shrink or stay stable, and also tracks side effec…

This early-stage trial tests a new drug called LDP, an antibody that blocks PD-L1, a protein cancers use to hide from the immune system. The study enrolls adults with advanced malignant tumors who have exhausted standard treatments. Researchers are evaluating the drug's safety, t…

This study tests whether a secure website with educational sessions, goal-setting, and tracking tools can help survivors of several cancers (including breast, prostate, colorectal, and others) improve their diet, increase physical activity, and manage weight. Participants are age…

This early-stage trial tests an experimental cell therapy called IBR854 in people with advanced solid tumors that cannot be surgically removed or have spread. The main goals are to check the treatment's safety and find the right dose. Participants receive the cells by infusion tw…

This trial compares three modern radiotherapy techniques—helical tomotherapy and two types of dynamic arc therapy (RapidArc and VMAT)—for treating prostate, cervical, and anal canal cancers that require pelvic lymph node irradiation. The goal is to determine which method is most …

This early-phase trial tests an experimental tablet called YZJ-5053 in people with advanced solid tumors who have no standard treatment options left. The main goals are to find a safe dose and check for side effects. Researchers will also look at how the drug moves through the bo…

This study tested whether adding Naderin (sodium nucleinate) to standard treatment could reduce complications in 75 patients with cancer, tuberculosis, or hepatitis C. The main group received Naderin plus standard therapy, while the control group received standard therapy alone. …

This study tested the drug pembrolizumab (Keytruda) as a follow-up treatment for one patient with a rare type of ovarian cancer called small cell carcinoma of the ovary, hypercalcemic type (SCCOHT). The goal was to see if the drug could help keep the cancer from coming back. Beca…

This Phase 1 trial tested an investigational oral drug called CFI-402257 in 52 people with advanced solid tumors, including breast cancer, that had stopped responding to standard treatments. The main goal was to find a safe dose and check how the drug moves through the body. It w…

This study tested a fixed-dose combination of two immunotherapy drugs, tiragolumab and atezolizumab, given together as a single infusion every three weeks. The trial enrolled 64 people with advanced solid tumors that express a protein called PD-L1. The main goal was to check the …

This pilot study tested whether combining high-dose radiation therapy with the immunotherapy drug pembrolizumab (Keytruda) could boost the immune system's ability to fight advanced solid tumors. Twenty-one patients with various advanced cancers received the combination either at …

This study compares a new formulation of the chemotherapy drug doxorubicin (Doxopeg) to the standard version (Caelyx) in people with advanced ovarian cancer or metastatic breast cancer. The goal is to see if the two drugs are absorbed and processed by the body in the same way. Pa…

This completed phase 2 trial tested whether the drug cediranib, given with chemotherapy, is safe for women with advanced ovarian cancer who are at risk of bowel obstruction. 30 participants received the combination. The study focused on whether the treatment caused serious bowel …

This phase 2 study tested a drug called retifanlimab, which helps the immune system attack cancer, either alone or combined with other targeted drugs. It enrolled 206 women with advanced or metastatic endometrial cancer that had worsened after platinum-based chemotherapy. The goa…

This early-phase trial tested a new type of vaccine made from a patient's own immune cells (dendritic cells) that are engineered to target a protein called WT1 found in many cancers. Ten people with advanced esophageal, pancreatic, ovarian, or liver cancer received six vaccines o…

This early-phase study tested whether adding indomethacin, a common anti-inflammatory drug, to standard platinum-based chemotherapy is safe for people with colorectal, esophageal, or ovarian cancers. The 13 participants received escalating doses of indomethacin alongside their ch…

This study compared two surgical approaches for early-stage cervical cancer: laparoscopic-assisted (minimally invasive) and open abdominal hysterectomy. Sixty women with stage IA1 to IB1 cervical cancer were randomly assigned to one of the two surgeries. Researchers measured surg…

This study looked at the long-term safety of several cancer drugs, including tislelizumab and pamiparib, in 404 people with advanced cancers. Participants had already been in an earlier trial of these drugs. The goal was to track serious side effects and see if patients could kee…

This early-phase trial tested a combination of three drugs—olaparib, metformin, and cyclophosphamide—in 35 women with recurrent advanced endometrial cancer that had already been treated with chemotherapy. The goal was to find a safe dose and see if the combination could stop the …

This phase 2 trial tested whether the immunotherapy drug pembrolizumab (Keytruda) could help keep cancer from growing in people with platinum-resistant ovarian, fallopian tube, or peritoneal cancer. After initial chemotherapy with paclitaxel, 20 participants received pembrolizuma…

This early-phase study tested a daily combination of two oral drugs, axitinib and everolimus, in 19 people with advanced solid tumors, particularly kidney cancer. The main goal was to find the safest dose by monitoring side effects in the first month. Researchers also tracked how…

This early-phase study tested a new drug called CCT3833 in 31 adults with advanced solid tumours, including melanoma. The main goal was to find a safe dose and check for side effects. Researchers measured how the drug moves through the body and looked for the best dose to use in …

This early-phase trial tested a new drug called PM14 in 126 people with advanced solid tumors that had no standard cure. The main goals were to find a safe dose and check for early signs of tumor shrinkage. The drug was given by IV infusion on different schedules. This is a first…

This study looked at the long-term safety of the cancer drug vismodegib in 19 patients with ovarian cancer, basal cell carcinoma, or metastatic colorectal cancer. All participants had previously taken vismodegib in an earlier Genentech trial and were expected to benefit from cont…

This phase 3 trial tested whether adding the immunotherapy drug atezolizumab to standard chemotherapy and bevacizumab helps women with advanced, persistent, or recurrent cervical cancer live longer. The study enrolled 410 participants and compared the new combination against the …

This study tested a new experimental treatment called HPVST cells in 32 people with HPV-related cancers that had returned or not responded to standard care. The cells are grown from the patient's own blood and trained to attack HPV-infected cancer cells. The goal was to find a sa…

This Phase 3 trial tested whether taking the drug selinexor as a maintenance pill after chemotherapy can help delay cancer progression in people with advanced or recurrent endometrial cancer. 263 participants who had responded to initial chemo were randomly assigned to receive ei…

This study tested a combination of two drugs, AZD6738 and olaparib, in 123 women with recurrent ovarian cancer. The goal was to see if the combo is safe and how well it shrinks tumors or delays cancer growth. Participants had either platinum-sensitive or platinum-resistant cancer…

This phase 2 trial tested a combination of three drugs—rucaparib, bevacizumab, and atezolizumab—in 30 people with recurrent or progressive endometrial cancer that had not responded to prior treatments. The goal was to see if the combination could shrink tumors or slow the cancer'…

This phase 3 trial tested whether a surgical procedure called laparotomy plus heated chemotherapy (HIPEC) could improve outcomes for colorectal cancer patients at high risk of cancer spreading in the abdomen. 150 patients who had already undergone surgery and chemotherapy were ra…

This phase 2 trial tested whether adding the immunotherapy drug atezolizumab to standard chemoradiation helps people with locally advanced cervical cancer. 189 participants received either the combination or standard treatment alone. The goal was to see if the combination delays …

This study tested a weight management program for young adult cancer survivors (ages 18-39) who have obesity and are within 5 years of finishing cancer treatment. The program combined healthy eating, physical activity, and symptom management to help reduce cardiovascular disease …

This early-phase study tested a combination of two chemotherapy drugs—weekly paclitaxel given through a vein and daily oral cyclophosphamide—in 28 adults with advanced cancer who had no other treatment options. The goal was to find the safest dose of paclitaxel when used with a f…

This study looked at 53 adults with advanced soft tissue sarcoma who had stable disease or improvement after 6 cycles of trabectedin. Half continued the drug, while the other half took a break (drug holiday). The goal was to see which approach better delays cancer progression and…

This study tested a new drug combination (tiragolumab plus atezolizumab) against atezolizumab alone in 172 people with advanced or returning cervical cancer that has a specific marker (PD-L1-positive). The goal was to see if the combination could shrink tumors better. Participant…

This early-stage trial tested a modified virus called TILT-123 in 32 people with advanced solid tumors that had not responded to standard treatments. The virus is designed to infect and kill cancer cells while releasing immune-boosting proteins. The main goal was to check safety …

This completed Phase 2 trial tested whether combining an immunotherapy drug (durvalumab) with an epigenetic drug (tazemetostat) can control advanced solid tumors like pancreatic, colorectal, and soft-tissue sarcoma. The study enrolled 164 adults and measured how well the combo sh…

This study tested whether a new drug called tisotumab vedotin works better than standard chemotherapy for people with cervical cancer that has spread or returned. Over 500 participants were randomly assigned to receive either the new drug or one of five chemotherapy options. The …

This large phase III trial tested whether using MRI scans to guide internal radiation (brachytherapy) works better than the traditional X-ray method for women with locally advanced cervical cancer. Over 1,000 participants received either MRI-based or X-ray-based brachytherapy. Th…

This study tested whether adding the HIV drug nelfinavir to standard chemoradiation helps people with advanced cervical cancer stay cancer-free longer. About 348 adults with stage III cervical cancer took part. One group got standard treatment, and the other got nelfinavir before…

This study looked at whether reducing the use of strong, broad-spectrum antibiotics in cancer patients with sepsis or septic shock is as safe as continuing them. The goal is to lower the risk of creating drug-resistant bacteria. Researchers compared a de-escalation strategy to st…

This trial studied 211 women with advanced ovarian cancer who were not candidates for upfront surgery. Researchers compared having surgery after 3 rounds of chemotherapy versus after 6 rounds. The goal was to see which timing leads to longer disease-free survival. All patients re…

This phase 3 trial tested whether a newer, more precise type of radiation (image-guided intensity modulated radiotherapy) could reduce long-term bowel problems compared to standard radiation in 300 women who had surgery for cervical cancer. The study focused on lowering severe bo…

This study looked at how effective and safe niraparib is for Korean women with epithelial ovarian cancer. It included 850 patients who took niraparib as maintenance therapy or as a later treatment. Researchers measured how long patients lived without their cancer getting worse an…

This phase 3 study tested whether combining the immunotherapy pembrolizumab with the targeted therapy lenvatinib works better than standard chemotherapy for women with advanced or recurrent endometrial cancer. Over 800 participants received either the drug combo or chemo. The goa…

This early-stage trial tested an experimental drug called CyPep-1, injected directly into tumors, either alone or with the immunotherapy pembrolizumab. The study involved 60 adults with advanced solid cancers that had stopped responding to standard treatments. The main goals were…

This early-phase trial tested an experimental drug called VS-6766, given alone or with everolimus, in 104 adults with advanced solid tumors or multiple myeloma that had stopped responding to standard treatments. The goal was to find a safe, tolerable dosing schedule and measure h…

This study tested a new drug called IMP4297 in 93 women with advanced ovarian cancer that has a BRCA1 or BRCA2 gene mutation and has come back after at least two prior treatments. The goal was to see if the drug can shrink tumors or slow the cancer's growth. The drug is taken as …

This early-phase trial tested a combination of two drugs—pembrolizumab (an immunotherapy) and nintedanib (a drug that blocks blood vessel growth)—in 196 adults with advanced solid tumors that had worsened after standard treatment. The main goal was to find the safest dose of nint…

This early-phase trial tested whether adding two chemotherapy drugs (6-mercaptopurine and 6-thioguanine) to an immunotherapy drug (Atezolizumab) could help treat advanced solid tumors that have stopped responding to standard treatments. The study enrolled 18 adults with metastati…

This phase 2 trial tested a drug called mirvetuximab soravtansine in 79 people with recurrent platinum-sensitive ovarian, peritoneal, or fallopian tube cancers that have high levels of a protein called folate receptor-alpha. The drug is given by IV every three weeks. The main goa…

This early-stage trial tested a new drug called MRX-2843 in 42 adults with advanced solid tumors that had spread or come back after other treatments. The main goal was to check safety and find the right dose. Researchers monitored side effects and how the drug moved through the b…

This early-stage trial tested a new biologic drug called ZGGS15 in 22 adults with advanced solid tumors who had no standard treatment options left. The main goals were to check safety, find the right dose, and look for early signs that the drug might control tumor growth. Partici…

This early-phase study tested an experimental oral drug called Q702 in 51 adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to find a safe dose and check for side effects, while also looking at whether the drug could shrink …

This study looked at 120 vulnerable women over 70 with advanced ovarian cancer. It compared three chemotherapy plans: standard two-drug therapy every three weeks, a single drug every three weeks, or a weekly two-drug schedule. The goal was to see which plan allowed patients to co…

This study tested whether giving the immunotherapy drug nivolumab directly into the abdomen is safe after extensive surgery and heated chemotherapy (HIPEC) for advanced ovarian cancer. 22 adults with recurrent ovarian, peritoneal, or fallopian tube cancer took part. The goal was …

This early-phase trial tested a personalized immunotherapy for people with advanced solid tumors. Doctors removed a sample of each patient's tumor, grew the immune cells (TILs) in a lab, and then infused them back along with another drug. The goal was to see if this approach is s…

This early-stage study tested a fixed-dose combination of two immunotherapy drugs (relatlimab and nivolumab) in 24 Chinese patients with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check safety, how the drugs move through the b…

This study tested two immunotherapy drugs, durvalumab and tremelimumab, given with chemotherapy before and after surgery for advanced ovarian cancer. The goal was to see if this combination is safe and feasible. About 69 women with stage IIIC to IV ovarian cancer took part. The r…

This study tested a combination of two drugs, pembrolizumab and lenvatinib, against standard chemotherapy for women with advanced or recurrent endometrial cancer. The goal was to see if the combo could slow cancer growth or improve survival better than chemo. The trial enrolled 1…

This pilot study tested whether a structured exercise program is feasible for young cancer survivors (ages 18-45) who have mild heart dysfunction after cancer treatment. The program, called CORE, is like cardiac rehab and aims to improve heart health, fitness, and quality of life…

This phase 2 trial tested whether adding the targeted drug cetuximab to standard chemoradiation (cisplatin plus radiation) improves outcomes for people with locally advanced cervical cancer (stages IB2 to IIIB). 76 participants were randomly assigned to receive either chemoradiat…

This early-phase trial tested a new immunotherapy drug called BDB001, alone or combined with atezolizumab (Tecentriq), in 40 adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check safety, find the best dose, and see if t…

This early-phase trial tested a new immunotherapy drug called BDB001, both alone and combined with pembrolizumab, in 87 adults with advanced solid tumors that had progressed after standard treatments. The main goals were to check safety and find the best dose. The study is comple…

This study offers continued access to tazemetostat for 58 people with various cancers who already benefited from the drug in earlier trials. The main goal is to monitor long-term safety and side effects. Participants must have shown clinical benefit from tazemetostat before joini…

This study tested a smartphone app to help young adult cancer survivors (ages 18-39) lose weight. The app tracked diet and activity as part of a behavioral weight loss program. The goal was to see if this approach was practical and well-liked by participants. The study involved 6…

This study tested a new oral drug called RP-3500 (camonsertib), alone or combined with talazoparib or gemcitabine, in 276 adults with advanced solid tumors that have certain genetic mutations. The main goals were to find the safest dose and check for early signs of tumor shrinkag…

This study tested a shorter course of pelvic radiation (about 1 week instead of the usual 5-6 weeks) given after hysterectomy for advanced endometrial cancer. The goal was to see if this shorter treatment causes fewer side effects while still controlling the cancer. The study inc…

This early-phase study tested whether adding the immunotherapy drug nivolumab to standard chemoradiation is safe for people with locally advanced cervical cancer. Twenty-one adults received nivolumab alongside cisplatin and radiation, followed by up to six months of nivolumab alo…

This Phase 2 trial tested whether adding afuresertib (an AKT inhibitor) to standard paclitaxel chemotherapy helps control platinum-resistant ovarian cancer better than paclitaxel alone. 150 women with this difficult-to-treat cancer participated. The study measured how long the ca…

This phase II trial tested whether adding the immunotherapy drug pembrolizumab (Keytruda) to standard chemotherapy before surgery helps women with stage IV ovarian cancer. 91 participants received either chemo alone or chemo plus pembrolizumab, followed by surgery. The goal was t…

This early-phase trial tested a new drug, Karonudib, in 63 people with advanced solid tumors that had not responded to standard treatments. The main goal was to check the drug's safety and find the best dose. Researchers also looked at how the drug moves through the body and any …

This early-phase trial tested the combination of two drugs—trabectedin and durvalumab—in 40 people with advanced soft-tissue sarcoma or ovarian cancer that had not responded to prior treatments. The main goal was to find a safe dose and check for side effects. Researchers also lo…

This early-phase trial tested an experimental immunotherapy called ELI-002 in 25 people with KRAS-mutated pancreatic, colorectal, lung, ovarian, or bile duct cancers who had signs of remaining disease after standard treatment. The therapy aims to train the immune system to attack…

Researchers in Cameroon are comparing a new smart speculum with a standard speculum to see which gives better comfort for women and clearer views of the cervix. Each participant receives both exams in random order, and clinicians use the smart speculum's images to make remote dia…

This study tests Cellvizio, a device that provides real-time, high-resolution views of tissues during gynecological surgery. Researchers want to see if it can help diagnose lesions and check surgical margins more accurately. The study will enroll 80 women undergoing laparoscopic …

This trial tests whether indocyanine green, a dye injected before surgery, can find sentinel lymph nodes as reliably as the standard technetium-99 radioactive tracer. About 744 adults with various cancers will receive both agents, and surgeons will compare detection rates using a…

This trial tests whether a vaginal self-sampling device can accurately detect high-risk human papillomavirus (HPV) compared to samples collected by a clinician. About 1,000 women aged 30-64, either regular screening attendees or those who haven't been screened in 3+ years, will p…

This study looks at whether a blood test that detects tumor DNA can find early signs of cancer returning in people treated for HPV-positive pelvic cancers (like cervical or anal cancer). Researchers will take blood samples from 172 patients during regular follow-up visits. The go…

This study tested a quick finger-prick blood test to see if cancer patients had been infected with COVID-19 in the past. Researchers enrolled 214 adults being treated for cancer. The goal was to find out how many had antibodies, including those without symptoms, to help clinics k…

This study tests a special SPECT imaging agent that seeks out a protein called LRRC15, found on many aggressive cancers like pancreatic, breast, lung, and brain tumors. The goal is to see if this scan can help doctors diagnose and stage these cancers more accurately. Healthy volu…

This study looked at whether women would be willing to collect their own urine sample for cervical cancer screening instead of a traditional swab. 173 women aged 31-49 at a French hospital tried it and answered questions about their experience. The goal was to see how acceptable …

This study looked at 45 patients whose HPV tests came back negative but had a late signal in the raw data. Researchers wanted to see if these late signals might actually indicate early cervical cell changes. By comparing different lab methods, they aim to improve how we interpret…

This study tested a new way to screen for cervical cancer using samples women collect themselves at home. Researchers wanted to see if a test that looks at DNA changes in HPV could better identify who truly needs follow-up care. About 294 women participated, and the goal was to m…

This study tested a new colposcopy method that uses a scoring system (Swede score) to better diagnose cervical precancer in women with abnormal screening results. Researchers enrolled 929 women referred for colposcopy to see if the scoring system could accurately identify precanc…

This study tested whether a simple checklist and blood test (the YEARS algorithm) can safely rule out pulmonary embolism (a blood clot in the lungs) in people with active cancer, compared to the standard approach of doing a CT scan on everyone. About 700 cancer patients with susp…

This study looked at whether adding a new tumor marker (HE4) and using special scoring systems (ROMA and RMI) can better tell the difference between harmless ovarian cysts and ovarian cancer. Researchers measured CA125 and HE4 levels in 221 women scheduled for ovarian cyst surger…

Researchers are testing whether a brief educational session helps Latina women who are overdue for cervical cancer screening use a mailed HPV self-sampling kit. Half of the participants receive the kit alone, and the other half also join a small-group session with a bilingual hea…

This study tests whether women in Kazakhstan will accept self-sampling kits for HPV detection, a key step in preventing cervical cancer. Researchers will distribute three different self-sampling devices to 1,000 women and survey their willingness to use them. The goal is to see i…

This large school-based study in Cambodia and Kenya tests whether adding age-appropriate lessons about HPV, the HPV vaccine, and cervical cancer to existing health classes can increase vaccination coverage and improve students' knowledge and attitudes. About 9,000 students in gra…

This study tests a program called 'Health is Wealth: A Cervical Health Program' designed to encourage cervical cancer screening among African American and Sub-Saharan African immigrant women. Participants attend a two-hour educational session and receive an HPV self-sampling kit …

This study tests whether limiting daily eating to an 8–10 hour window can improve metabolic health and potentially lower the risk of endometrial cancer. Overweight or obese Native Hawaiian/Pacific Islander women at elevated risk will follow a time-restricted eating schedule for s…

This study tests whether the drug SENS-401 can prevent hearing loss caused by cisplatin, a common chemotherapy. Adults with cancer who are scheduled to receive cisplatin take SENS-401 before, during, and after treatment. Hearing is measured with a standard test to see if the drug…

This study tested whether a taurolidine-citrate solution (TauroLock) placed in the catheter between treatments can prevent bloodstream infections in adults with solid tumors receiving IV anti-cancer therapy. 162 patients were randomly assigned to get either the TauroLock solution…

This study tested a program called Game Changers for Cervical Cancer Prevention (GC-CCP) in Uganda. It trained women who had already been screened to encourage their friends and family to get screened too. The trial involved 936 participants and compared the program to usual care…

This study looked at whether giving the Gardasil 9 HPV vaccine to women at the same time as surgery for abnormal cervical cells (CIN) can help clear the virus and prevent future infections. About 1,100 women aged 18-55 took part. The goal was to see if the vaccine reduces the cha…

This study tested whether offering a vaginal self-sampling kit directly to women aged 50-65 who had not had a cervical smear in over three years would increase screening participation. Women received a kit to use at home and mail to a lab for HPV testing. The goal was to see how …

This study tested a two-step screening process to find postmenopausal women at higher risk for endometrial cancer. Those identified as high-risk received a hormone challenge test and, if positive, standard care plus a lifestyle program. The goal was to see if this approach is pra…

This phase 3 trial tested whether a biologic called IMM-101 could reduce severe respiratory infections, including COVID-19, in cancer patients at higher risk. 195 participants either received three doses of IMM-101 or were simply observed. The goal was to see if the treatment cou…

This study tested whether mailing HPV self-test kits to women who are overdue for cervical cancer screening could increase participation. Over 2,400 underserved women in Texas were randomly assigned to receive a kit or standard phone reminders. The goal was to see if the at-home …

Researchers test a 10-week lifestyle program for people who have finished cancer treatment. The program combines structured exercise, nutrition counseling, and behavioral therapy. They compare it with a waitlist group to see how it affects cardiorespiratory fitness and body weigh…

Researchers at the University of Oklahoma are testing a mobile health program designed to help adults receiving chemotherapy for metastatic breast or gynecologic cancer stay physically active. The program combines a wearable activity tracker, behavior change techniques, acceptanc…

This study is testing a mobile health app designed to help cancer survivors manage pain and other symptoms after treatment. Twenty-five survivors who have finished cancer treatment but still have pain will use the app for one week, receiving helpful messages and completing daily …

This study tests whether adding a special yoga and physiotherapy program to standard care can lower stress in women receiving brachytherapy for cervical cancer. About 98 women will take part. The program includes gentle movement and breathing exercises designed to be safe during …

This study tests a pre-surgical toolkit (OPTI-Surg) designed to help older cancer patients recover more quickly after major surgery. The toolkit provides recommendations before surgery to improve physical function and reduce complications. About 325 participants with various canc…

This study looked at 2,000 adults with solid tumors to find the best dose of olanzapine for preventing nausea and vomiting caused by strong chemotherapy. Researchers compared 2.5 mg, 5 mg, and 10 mg doses to see which works best with the fewest side effects like daytime sleepines…

This completed Phase 2 trial tested whether formal hypnosis, alongside standard care, could reduce anxiety and pain in 68 cancer patients undergoing brachytherapy. Patients received either standard care with Kalinox or standard care plus formal hypnosis. The study measured anxiet…

This study tested an experimental oral drug called Trichomylin® in 11 adults with advanced cancer who had moderate to severe pain despite taking strong opioids. The goal was to see if the drug is safe and can provide additional pain relief. Participants took the drug twice daily,…

This study tests a program that helps caregivers of teens and young adults (ages 15-26) with cancer find resources for financial and social needs. About 60 caregiver-patient pairs will take part. The goal is to see if this support reduces stress and improves well-being.

This trial tests whether wearing a grounding patch at night improves sleep quality in cancer patients who have insomnia while in the hospital. The patch is a hydrogel sticker on the forehead, connected by a cord to a true earth connection, which may lower the body's electrical vo…

This trial tests whether an AI emotional companion app can improve depression, anxiety, and demoralization in adults with advanced cancer. Participants use a mobile app where a virtual character holds conversations, reads emotional cues, and offers a link to a human hotline if di…

This trial tests whether art therapy can reduce physical and psychological symptoms in cancer patients receiving chemotherapy or immunotherapy. Over six treatment sessions, participants engage in artistic activities like painting, drawing, or clay work, guided by an art therapist…

This trial tests whether heated traditional Chinese medicine plasters can help cancer patients recover from chemotherapy-induced anemia and low blood cell counts. Participants apply the plaster to a specific point on the navel for one hour daily over two weeks. Researchers compar…

This study tests whether adding olanzapine to standard anti-nausea medicines can better control vomiting in children receiving strong chemotherapy. About 200 children will be randomly assigned to get either olanzapine or a placebo. The goal is to see if olanzapine helps more kids…

This study looked at whether laughter yoga could help cancer patients going through chemotherapy. 55 patients were split into two groups: one did weekly 40-minute laughter yoga sessions for four weeks, while the other received standard care. After four weeks, the laughter yoga gr…

This trial tests whether the Benson Relaxation Technique, a simple 15-minute guided relaxation exercise, can reduce pain, insomnia, nausea, vomiting, and retching in adults with cancer who are admitted to intensive care. Participants will practice the technique, which involves si…

This study tested a program to help cancer survivors quit smoking and manage pain. Nineteen survivors received counseling and the medication varenicline (Chantix). The goal was to see if the program was practical and helpful, not yet to prove it works.

This study tests whether a conversation game called 'Hello' can help people with cancer and their loved ones discuss advance care planning—decisions about future medical care. Participants will play either the Hello game or a similar conversation game, complete questionnaires, an…

This study tests whether a 16-week digital pelvic floor rehabilitation program is feasible for women who have been treated for cervical cancer within the past five years. The program includes supervised group exercise sessions and home exercises, along with information on dilator…

This trial tests whether a combined nerve block can provide better pain relief than standard local anesthesia for cancer patients undergoing chemoport implantation. The study will compare the two approaches in 80 adults, measuring the need for extra pain medication during the pro…

This trial tests whether laser acupuncture, a non-invasive therapy using low-intensity light on traditional acupoints, can relieve constipation in people with advanced cancer. Participants are adults with advanced cancer who have constipation despite using laxatives. The study me…

This early-stage trial is testing whether a topical solution containing calcitriol, a form of vitamin D, can safely reduce hair loss in adults receiving taxane-based chemotherapy for breast, gynecologic, or other solid tumors. Participants apply the solution to their scalp twice …

This phase 2 trial tests whether inhaling a blend of peppermint and lemon essential oils can reduce nausea and vomiting in people receiving their first chemotherapy for a solid tumor. Participants will inhale the oils four times daily and whenever nausea strikes, with symptoms tr…

This study explores whether engaging in positive activities can improve emotional well-being and quality of life for Asian American cancer patients and their caregivers. Participants, who are within a year of a cancer diagnosis and undergoing treatment, along with their caregiver…

This trial tests whether combining pranayama breathing exercises with music listening can help manage fatigue and improve quality of life in cancer patients receiving immunotherapy. Sixty participants are split into two groups: one receives the integrative therapy alongside their…

This trial tests whether a new care approach, called PediQUEST Response, can improve quality of life for children, adolescents, and young adults with advanced cancer. Participants use an app to regularly report symptoms and quality of life, and a palliative care team receives the…

This study tests whether a music-assisted mandala coloring activity can improve psychological well-being and quality of life in adults receiving their first chemotherapy treatment for cancer. Participants will color mandalas weekly for 8 weeks, guided by an instructional video, a…

This study tests a psychosocial program called Conquer Fear Support (CFS) for people with stage III or IV lung or gynecologic cancer who are experiencing fear of cancer progression. The program includes psychoeducation, attention training, worry management, and detached mindfulne…

This study looks at whether a program called prehabilitation—which helps patients get stronger and healthier before surgery—can lower the chance of problems after surgery for advanced ovarian cancer. About 146 women having surgery for ovarian cancer will take part. The goal is to…

This study tests whether using a virtual reality headset during PICC line placement can reduce anxiety and pain in cancer patients. About 120 adults will be randomly assigned to either receive VR plus standard care or standard care alone. The goal is to see if this non-drug appro…

This study tested whether monthly 45-minute psychological interviews over 6 months could reduce post-traumatic stress symptoms in cancer patients affected by the COVID-19 pandemic. It included 29 adults with solid tumors who had moderate to high PTSD symptoms. The goal was to see…

This trial tests whether a web-based educational program can help people with advanced cancer reduce their preference for aggressive life-sustaining treatments. Participants are randomly assigned to receive either the web program plus an informational leaflet, or the leaflet alon…

This study tests PAfitME™, a telehealth program that uses personalized motion exergames to help young adult cancer survivors (ages 18–39) improve their physical function. The program is tailored to each person's fitness level, fatigue, and pain. Researchers will see if it is feas…

This study tests whether limiting food intake to a 10-hour window each day for 12 weeks can reduce persistent fatigue in cancer survivors who completed treatment 2 months to 2 years ago. Half the participants follow the eating schedule; the other half receive general healthy life…

This study tests whether graded motor imagery—a brain-based therapy involving left/right judgment, imagined movements, and mirror exercises—can relieve nerve pain and improve leg function in cancer patients with chemotherapy-induced peripheral neuropathy. Half the participants wi…

This study tested a 4-week exercise program before surgery (prehabilitation) in 34 women with cervical cancer. The program included aerobic, resistance, and pelvic floor exercises. Results suggest it may improve pelvic floor strength and shorten hospital stays compared to standar…

This study tests whether isometric hand exercises or applying dry heat can make veins fuller and easier to see in cancer patients receiving chemotherapy. A total of 180 patients were randomly assigned to one of three groups: isometric exercise, dry heat, or standard care. The goa…

This study tested a 5-week digital program called EMPOWER that teaches emotion regulation skills to adolescent and young adult cancer survivors. 352 participants completed weekly lessons and brief daily exercises. The goal was to see if the program could improve positive feelings…

This study tests whether listening to traditional Chinese guzheng music and smelling lavender essential oil can reduce anxiety in cancer patients undergoing MRI scans. Participants are randomly assigned to receive music, aromatherapy, both, or standard care. The researchers will …

This study tests whether acupuncture using tiny, semi-permanent needles can prevent diarrhea caused by the chemotherapy drug irinotecan in children with solid tumors. About 22 children will receive the acupuncture during their second round of chemo, and researchers will measure p…

This study tests a smartphone app called STAMP+CBT that combines pain coping skills training with medication support for people with advanced cancer who have chronic pain. The app provides tailored education and real-time feedback to help users manage their pain. Researchers want…

This study is testing whether a mobile app that combines daily symptom reports with Fitbit data can help cancer patients better manage side effects during chemotherapy. Fifty adults with solid tumors will use the app for 90 days, receiving tips for mild symptoms and alerts to con…

This study looked at whether teaching cancer patients about their portable chemotherapy pump (elastomeric pump) can make them feel more comfortable and less anxious. 70 adults receiving 5-FU treatment were split into two groups: one got extra education and a booklet, the other go…

This pilot study tested whether a 12-week exercise program designed for Punjabi-speaking South Asian cancer patients and their support persons is practical and well-liked. Twelve participants did twice-weekly exercise sessions and filled out questionnaires. The goal was to see if…

This study tested a music therapy program called Meraki for cancer patients receiving palliative care. The goal was to see if three music sessions could improve emotional well-being, reduce anxiety and depression, and boost quality of life. Researchers enrolled 80 patients and me…

This study looked at whether a one-hour hypnosis session, done 5 to 15 days before a hysterectomy for pelvic gynecological cancer, could lower anxiety around the time of surgery. Twenty-nine women participated, and the hypnosis was guided by a trained nurse. The main goal was to …

This study tested a 3-week program that helps cancer patients identify their personal strengths (like hobbies, social support, or personal qualities) and use them to cope better. 32 adults with different cancers took part in card-sorting sessions, phone calls, and home exercises.…

This study tested a 6-session therapy called Acceptance and Commitment Therapy (ACT) for cancer patients at risk of opioid misuse. 40 adults with cancer and a high score on an opioid risk tool participated. The goal was to see if the therapy was feasible and acceptable, not yet t…

This study tested whether coloring mandala patterns can reduce nausea, vomiting, and fatigue, and improve psychological well-being in cancer patients receiving chemotherapy. 85 patients were split into a coloring group and a control group. The coloring session lasted 20-30 minute…

This study tested a special pain coping skills program for people with advanced solid tumor cancer who have pain that interferes with daily activities. 211 patients were randomly assigned to either the program or standard care. The program taught ways to manage pain and find mean…

This study tested a 12-week online mind-body program for adults with chronic conditions like heart failure, cancer, and liver disease. The program included mindful movement, meditation, breathwork, and coping skills. Researchers measured changes in anxiety, depression, fatigue, a…

This pilot study tested whether taking a green tea extract (EGCG) plus vitamin C daily for 12 weeks is safe and feasible for older cancer survivors who are frail or pre-frail. The study enrolled 24 people aged 65 and older who had completed cancer treatment. The main goal was to …

This study tested a mobile app called SyMon-SAYS that lets children with cancer report their symptoms weekly to their doctors. The goal was to see if using the app helps manage symptoms and improve quality of life. 216 children and their parents took part, with some using the app…

This study tested whether a program called PRISM (Promoting Resilience in Stress Management) could help young adults aged 18-39 who have cancer or desmoid tumors manage anxiety and depression. The program teaches skills like stress management, goal setting, and positive thinking.…

This study tested a 9-session virtual mind-body program (SMART-3RP) to see if it helps caregivers of cancer survivors feel less stressed and more resilient. It compared the program to a standard online support group. The trial enrolled 94 participants and focused on whether the p…

This study tested an online program to help cancer patients with insomnia. It included 348 adults with cancer who had trouble sleeping. The program used cognitive-behavioral techniques and aimed to see who might need extra help from a professional.

This study tested a new way to follow up with gynecologic cancer survivors. Instead of seeing a doctor every time, patients saw a nurse at every other visit and used a smartphone app to help manage their health. The goal was to see if this approach improved self-management skills…

This study tested whether using a low-frequency laser on an acupuncture point (P6) can help prevent nausea and vomiting caused by chemotherapy in children aged 2 to 20. The 30 participants received the laser treatment alongside standard anti-nausea drugs. The goal was to see if a…

This study tested a program called YATAC, designed to help young adults (ages 18-39) recover from cancer and return to everyday life. The program covers goal-setting, managing daily life, staying active, coping with emotions, education, work, finances, relationships, and peer sup…

This study tested a home-based cognitive training program called BrainHQ in 60 women with gynecologic cancers who had memory or thinking problems after chemotherapy. Participants used the app for about 2.5 hours per week for 10 weeks. The goal was to see if the program was practi…

This study tested whether placing a small drain in the belly to remove leftover gas after laparoscopic gynecologic surgery reduces shoulder and rib pain. 202 women were randomly assigned to get the drain or standard manual gas release. The goal was to see if fewer women in the dr…

This study tested a 6-month program called CancerPEP that sends daily emails to cancer patients and survivors with tips on exercise, yoga, stress reduction, and healthy eating. The goal was to see if the program is practical and helps improve mental and physical health. 104 adult…

This study tested whether adding ketoprofen to standard paracetamol (acetaminophen) can better control pain in patients receiving brachytherapy for cervical or upper airway/digestive tract cancers. Sixty-eight adults were randomly assigned to receive either paracetamol alone or p…

This study tested an online educational program for cancer patients receiving chemotherapy. The program included video sessions, peer discussions, and digital materials to help with symptom management and emotional coping. Researchers compared 212 patients who used the program to…

This study looked at whether cancer patients prefer doing yoga online or in a studio during their treatment. 163 people with cancer chose their preferred setting and attended weekly group yoga for 12 weeks. Researchers measured quality of life and interviewed participants about t…

This study tested a stepped-care telehealth program for cancer survivors living in rural areas who experience anxiety, depression, or sleep problems. Participants received either low-intensity check-ins or high-intensity phone therapy with a licensed therapist, depending on sympt…

This study tested a smartphone app called POSTHOC that helps cancer survivors manage symptoms and track healthy behaviors after finishing treatment. Fifty-one adults who recently completed cancer therapy used the app or received standard care for 12 weeks. The goal was to see if …

This study tested whether a combination of slow, guided breathing (called cardiac coherence) and a hypnosis session could help women feel less anxious before breast or gynecologic cancer surgery. Fifty-three women participated, practicing the breathing technique several times a d…

This study tested whether asking cancer patients to complete a symptom questionnaire online before their doctor visit could help identify who might benefit from a palliative care referral. Forty adults with advanced cancer participated. The goal was to see if this approach is pra…

This study looked at whether a 12-week adapted physical activity program could help cancer patients feel less tired and improve their quality of life. 37 adults with different cancer types and treatments took part. Researchers measured fatigue, quality of life, and fear of moveme…

This study tested a program that teaches couples communication skills when one partner has advanced cancer. About 440 patients and their partners took part, with half receiving the training and half getting general healthy living information. The goal was to see if the training c…

This study tested an 8-week phone- and app-based program designed to increase hope and reduce life disruption in young adults who have finished cancer treatment. 155 survivors participated in a randomized trial comparing the hope program to a control group. The goal was to see if…

This study tested a program called CAFÉ, where financial navigators helped cancer patients with money concerns after diagnosis. The goal was to reduce financial hardship and improve quality of life. 371 patients from two Kaiser Permanente regions took part. The program provided p…

This study tested whether a telemonitoring app called Cureety could reduce the number of phone calls hospital staff receive from cancer patients starting oral or IV treatment. 86 adults with cancer were randomly assigned to standard care or standard care plus the app. The goal wa…

This study tested whether a mobile app that lets cancer patients report their symptoms to their doctor can reduce unplanned hospital visits. 166 adults with solid cancers on systemic therapy participated. Half used the app before clinic visits, while the other half had usual care…

This study tested whether an 8-week sleep coaching program delivered through a smartphone app is practical and acceptable for cancer survivors and their bedroom partners. Forty participants were enrolled to see if they would stick with the program and find it helpful. The goal wa…

This study tested whether an online education program helps gynecologic cancer patients better manage side effects after brachytherapy. 150 patients were randomly assigned to receive either the online program plus standard care or standard care alone. The goal was to see if the p…

This study tested a short-term talking therapy (psychodynamic psychotherapy) for 24 adults with advanced solid tumors and high psychological distress. The goal was to see if the therapy is safe, acceptable, and feasible, not to cure the cancer. Results will help design larger stu…

This study looked at whether a walking platform with fall protection and support is practical for older cancer patients (over 70) during hospital stays. 45 patients were enrolled to see if they would use it at least twice for 6 minutes or more. The goal was to help them stay acti…

This study tested a program called PRISM that teaches stress management, goal-setting, and coping skills to adolescents and young adults (ages 12-24) with advanced cancer. Researchers wanted to see if it could improve quality of life and reduce anxiety and depression. The program…

This study tested a program to help older cancer patients get stronger before and after surgery. 148 patients aged 70+ (or 60+ with other health issues) took part. The program included exercise, nutrition advice, and education to reduce complications and improve recovery.

This study tested if the drug Akynzeo can prevent nausea and vomiting in cancer patients getting moderate chemotherapy who are at high risk based on a special prediction tool. Over 400 adults took part. The goal was to see if Akynzeo works better than standard care over three rou…

This study tested a telehealth program called Dyadic Life Review (DLR) for older adults (65+) with advanced cancer and mild cognitive impairment, along with their caregivers. The program involved 8 weekly video sessions where patients and caregivers shared memories from different…

This study tested whether mangafodipir, an MRI contrast agent with antioxidant properties, could reduce nerve damage caused by oxaliplatin chemotherapy. Researchers enrolled 23 cancer patients who already had moderate nerve problems from oxaliplatin but needed to continue treatme…

This study tested a mobile app called STAMP+CBT for advanced cancer patients with chronic pain. The app helps patients track their pain, mood, and opioid use while providing tailored education and cognitive behavioral therapy (CBT) exercises. Fifty-two patients used the app for 4…

This completed pilot study tested a 12-week home-based exercise program for cancer survivors who also have diabetes or hypertension. The program used a wearable device and smartphone app to track activity and provide feedback, with options like walking, yoga, or strength exercise…

This study tested a mobile app designed to help doctors keep track of symptoms in women with advanced ovarian cancer. Ten patients used the app, which combined their medical records with regular symptom reports. The goal was to see if this information helped the care team make be…

This study looked at whether a 12-week home exercise program using mobile technology could reduce fatigue in cancer survivors. 110 adults who had finished cancer treatment or were on immunotherapy took part. Some also tried acupressure or brief mindfulness exercises. The goal was…

This study tested whether using a virtual reality headset during cancer surgery under local anesthesia can reduce pain and anxiety. 42 adults with cancer were randomly assigned to receive either local anesthesia alone or local anesthesia plus VR. The VR used hypnosis and relaxati…

This study tested a patient education program for 167 cancer patients with moderate to severe pain. The program included identifying patient needs, setting goals, and tailored learning activities. Researchers measured whether the program reduced how much pain interfered with dail…

This study tested a web-based program to help children aged 8-17 with cancer adjust to returning to school. The program included modules for children, parents, teachers, and peers, focusing on communication, coping, and social skills. Twenty children participated, and researchers…

This study tested whether a digital platform called Cureety could reduce the number of phone calls hospital staff need to make to cancer patients before their injectable treatments. 192 adults starting injectable cancer therapy in France were randomly assigned to usual care or us…

This study tested three types of medicinal cannabis oil (with different levels of THC and CBD) against a placebo in 91 cancer patients. The goal was to see which oil, if any, helps with pain, nausea, anxiety, and sleep problems. Each patient tried multiple oils and a placebo in a…

This completed phase 3 trial tested whether taking psyllium husk fiber capsules during pelvic radiation therapy could reduce gut inflammation and urgency symptoms. 354 adults with pelvic cancers (like rectal, prostate, or gynecological) took either fiber or placebo capsules daily…

This study tested whether a numbing medicine called ropivacaine, given through a chest tube, can reduce severe pain after lung cancer surgery. 90 adults having a thoracotomy (chest opening) for cancer received either ropivacaine or a saltwater placebo every 6 hours for 2 days. Th…

This study looked at whether four well-being treatments — foot reflexology, socio-aesthetics (beauty and skincare), sophrology (a relaxation technique), and singing — can help reduce pain in people with cancer. 180 adult cancer patients took part. The goal was to see if these non…

This study tested two simple changes to hospital wheelchairs: a holder to keep IV poles attached during transport, and a more comfortable seat. Researchers wanted to see if these upgrades could shorten travel time and reduce pain for cancer patients being moved around the hospita…

This study gives questionnaires to patients, interpreters, and healthcare professionals to understand how language and cultural differences impact care for women with gynecologic cancer. The goal is to identify barriers and improve the patient experience. About 45 people will tak…

Researchers are studying whether daily step counts and other smartwatch measurements can predict which cancer patients will be readmitted to the hospital after discharge. Adults who have just left an oncology ward wear a Huawei smartwatch for 30 days to track steps, heart rate, a…

This study checks for muscle loss (sarcopenia) in 25 women with advanced ovarian cancer before they start chemotherapy. Using CT scans, researchers want to see how common this condition is and if it affects treatment timing. The goal is to better understand how muscle health rela…

This study looked at the emotional and practical challenges faced by patients with incurable cancer and their caregivers when planning to return home for end-of-life care. Researchers measured how each person perceived the burden, using surveys and statistical analysis to find fa…

This study followed 150 people with solid tumors who were starting immunotherapy (immune checkpoint inhibitors) as part of their regular care. Researchers collected data on side effects and asked patients to fill out questionnaires before each treatment. The goal was to better un…

This completed study enrolled 377 individuals and families with a high risk of breast or ovarian cancer due to known or suspected genetic factors. Researchers collected medical records, questionnaires, and biological samples to better understand the disease's natural history and …

Researchers are testing two ways to train VA primary care clinicians to hold goals of care conversations with veterans who have serious illnesses such as cancer, heart failure, or dementia. One approach gives clinicians written materials and online training. The other adds team f…

This study looked at whether offering genetic testing to all young adults with cancer (ages 18-39) is better than only testing those who meet certain guidelines. About 749 participants were randomly assigned to either universal testing with a broad gene panel or standard testing …

Researchers at a large hospital in Seoul reviewed records from nearly 33,000 adults who had curative-intent surgery for one of seven cancers in the abdomen or pelvis: pancreatic, gastric, rectal, cervical, endometrial, kidney, or prostate. They grouped patients by whether they re…

This phase 3 trial compares a less invasive sentinel node biopsy approach to standard staging methods in 262 women with early-stage endometrial cancer at intermediate or high risk of recurrence. The goal is to see if the sentinel node policy reduces surgical complications while s…

This study followed over 46,000 women in the Netherlands who tested positive for HPV and had mild abnormal Pap results. Researchers tracked how many developed cervical cancer within five years. The goal was to see if these women could safely have fewer follow-up tests, making scr…

Researchers want to learn which molecules on cancer cells the immune system attacks when checkpoint inhibitor drugs work well. They collect tumor and blood samples from adults with solid tumors who respond to these drugs, either during treatment or after surgery. The team then se…

This study is testing whether a green dye called ICG can help surgeons see tumors more clearly during surgery in children and teens with solid tumors. The dye is injected before surgery and makes tumor tissue glow under a special camera. The goal is to see if this technique helps…

Researchers in seven European and Latin American countries ask bereaved relatives to complete the CODE questionnaire about two months after a family member died of cancer in hospital. The survey asks whether patients were treated with dignity and respect and whether relatives fel…

This large observational study looks at whether getting an mRNA COVID-19 vaccine shortly before or after starting immune checkpoint inhibitor therapy is linked to longer survival in adults with cancer. Using data from nearly 100,000 patients in France, researchers are comparing t…

This trial tests whether an AI-supported chatbot can boost nursing students' knowledge of gynecologic cancers and their clinical decision-making skills. Third-year nursing students who have completed their obstetrics and gynecology course will be randomly assigned to either use t…

This study tests a digital platform called ConnectedNest that helps cancer patients find and connect with social services like housing assistance, food aid, and financial help. About 400 adults with cancer in Minnesota will use the platform for 90 days. Researchers will measure i…

This study asks whether measuring circulating endothelial cells (CECs), cells shed from blood vessel walls, can predict how well ovarian cancer patients respond to standard chemotherapy with or without bevacizumab. Researchers will use a standardized flow cytometry method to coun…

This study examines whether a routine blood test called Mean Platelet Volume (MPV), taken when a cancer patient is admitted to the intensive care unit (ICU), can help predict their risk of dying. Researchers will review the medical records of 425 adult cancer patients who stayed …

This study looks at proteins in the blood of women with ovarian, peritoneal, or fallopian tube cancer who are in remission. The goal is to find a protein pattern, or 'fingerprint,' that signals when the cancer might come back. Researchers followed 119 women with stage III or IV c…

This study tested a document called Voicing My CHOiCES, designed to help young adults (ages 18-39) with serious illnesses like cancer or HIV discuss their care preferences. Participants filled out questionnaires about anxiety, social support, and communication, then reviewed the …

This pilot study tests a program to help young female cancer survivors in rural Imperial County, California, get reproductive health care that matches their personal goals. The program includes a quick needs assessment during oncology visits, followed by a session with a social w…

This study explored how family members share health information about genetic diseases like sickle cell, diabetes, and cancer. Over 1,000 adults completed surveys or interviews about their family health history and support. The goal was to understand social and relational factors…

This observational study will examine the molecular and epidemiological characteristics of endometrial cancer in Brazil, focusing on women diagnosed between 2016 and 2019. Researchers will analyze tumor samples for genetic mutations and biomarkers, and collect data on demographic…

This study looked at how cancer treatment changes patients' ability to stick with a Mediterranean diet. Researchers followed 116 patients starting chemotherapy or immunotherapy, checking their diet adherence and sensory changes (taste and smell) at the start and after 9 weeks. Th…

This trial tests whether a 15-minute educational video and a list of suggested questions can improve understanding of immunotherapy among patients with advanced cancer and their caregivers. Participants are randomly assigned to receive the educational materials or usual care, and…

This study tests whether a 3.5-minute educational video shown before a doctor's visit helps cancer patients understand radiation therapy better than standard verbal instructions alone. One hundred patients scheduled for radiation will be randomly assigned to receive either the vi…

This study tested a co-designed nutritional training program for 20 oncology nurses in Vietnam. The program included a three-day workshop with theory and hands-on practice, focusing on managing diet-related side effects of cancer treatment like nausea and diarrhea. Researchers me…

This study tests whether giving gynecologic cancer patients a list of questions to ask their doctor improves their confidence, reduces distress, and builds trust. About 70 adults with newly diagnosed or suspected gynecologic cancer will either receive the question list or usual c…

This study looked at skin problems caused by targeted cancer therapies. Researchers followed 141 cancer patients starting these treatments, recording any skin reactions through exams and photos. The goal was to better understand why these side effects happen and how to manage the…

This trial asks whether the type of red blood cell transfusion given during cancer surgery affects the body's immune response. It compares standard transfusions with leuko-reduced ones, which have white blood cells removed. The study involves 150 cancer patients undergoing curati…

This study looks at whether a short risk-assessment tool, called the CARG score, can predict severe side effects from chemotherapy in cancer patients aged 70 and older. Participants will answer questions about their health and daily function before starting a new chemotherapy reg…

This study looked at whether a special website or coaching phone calls could help more people with a personal or family history of certain cancers get genetic testing. Over 800 participants were randomly assigned to one of these two methods or to standard care. The goal was to se…

This trial explores whether a blood test measuring reticulocyte hemoglobin content (RET-He) can predict how well cancer patients with anemia will respond to intravenous iron treatment. The study involves adults with solid tumors who have functional iron deficiency. By checking RE…

This study is testing a new smartphone app designed to help cancer patients remember to take their oral anticancer medications and report any side effects. The app also helps patients communicate with their care team and find support for financial or social needs. Researchers wil…

This study uses an online questionnaire to explore how people with past or active cancer in France use self-medication, including non-prescription drugs, herbal remedies, and supplements. It aims to understand what products they take, why, and where they get them. The findings co…

This study investigates whether lymph nodes in the lower abdomen, called the inferior epigastric lymph node basin, might be an early stop for ovarian cancer spreading from the peritoneum. Researchers will biopsy these nodes in 20 patients undergoing surgery for ovarian peritoneal…

This study looks at whether the virus that causes COVID-19 can be found in the semen of men with cancer who are storing sperm before treatment. Researchers will test both the fluid and the sperm cells for the virus and compare results with nasal swabs and blood tests. The goal is…

This study looks at whether getting a yearly LDL cholesterol test could help cancer survivors avoid serious heart problems like heart attacks and strokes. Researchers will analyze health records from over a million cancer survivors in Korea, comparing those who had the test with …

This study reviews existing medical records to understand how blood clots (VTE) are treated in people with active cancer or a history of cancer. Researchers will look at which blood thinners are used, how often clots come back, and the costs involved. No new treatments are given—…

This study examines how children under 18 with cancer or a history of a stem cell transplant do when they need a machine called ECMO to help them breathe. Researchers looked at bleeding, infections, and survival rates in children treated at one hospital, and compared survival wit…

This study looks at what factors increase the risk of a serious complication called anastomotic leakage after ovarian cancer surgery. Researchers will analyze data from 401 patients to build a prediction model. The goal is to help surgeons identify high-risk patients early and ta…

This study tests whether a structured face-to-face education program can improve women's knowledge about cervical cancer and their attitudes toward the HPV vaccine. One hundred women aged 18-49 in Turkey will be split into two groups: one receives the education, the other gets ro…

This study looks at whether using text messages to screen for depression is practical and well-liked by cancer survivors. About 60 adults with cancer will be asked to respond to a short depression questionnaire via text. The goal is to see if this method works better than the usu…

This study tests a digital education program designed to help newly diagnosed women with gynecological cancer learn about egg freezing (oocyte cryopreservation). The program uses videos, images, WhatsApp, and online meetings to teach about fertility preservation options. Research…

This study looks at how lung ultrasound can help find lung issues early in women who are critically ill due to pregnancy complications or gynecologic cancer. Researchers will check for different lung ultrasound patterns and see if they relate to patient outcomes like death or nee…

This observational study follows cancer patients undergoing radiotherapy to understand how psychological distress changes over time and whether it affects clinical outcomes like missed appointments or hospitalizations. Participants complete weekly surveys rating their distress an…

This study follows 67 women with cervical cancer for one year after they finish radiation therapy. Researchers want to see how their quality of life, including physical and emotional well-being, changes over time. Participants fill out questionnaires about symptoms like fatigue, …

This study collects medical information and biological samples (blood, urine, stool, etc.) from 32 cancer patients starting or restarting immunotherapy. The goal is to build a research database to better understand why some patients develop immune-related side effects and how to …

This study looks at how proteins in the blood change in women with ovarian cancer as they go through standard treatment. Researchers collected blood samples before surgery, after surgery, and after chemotherapy to see if these protein shifts could give a fuller picture of how the…

This study looks at whether a 12-week program of cooking demonstrations, recipe cards, and free fruit and vegetable bundles can help cancer survivors eat healthier. Only 11 people are taking part, and the main goal is to see if such a program is practical and keeps people interes…

This study investigates how often cancer patients with COVID-19 develop dangerous blood clots (venous thromboembolism). Researchers will screen participants using ultrasound and blood tests to detect clots, whether or not they cause symptoms. The goal is to understand the true ra…

This study looked at whether having a special consultation with a radiotherapy technician (called a manipulator) helps cancer patients feel more informed about their treatment. Researchers enrolled 308 adults with various cancers who were getting radiation therapy. They compared …

This study collects and analyzes health records from 10,000 cancer patients across multiple sites. Researchers will use this real-world data to better understand patient populations, improve clinical trial design, and support drug development. No new treatments are tested—the goa…

This study looked at how certain enzymes called matrix metalloproteinases (MMPs) and their inhibitors relate to human papillomavirus (HPV) in cervical dysplasia and cancer. Researchers collected tissue and cell samples from 216 women with different stages of cervical lesions. The…

This study tested whether a smartphone app called QuestOnco can reliably track side effects in 134 adult cancer patients receiving active treatment. Patients used the app to report symptoms, and researchers compared those reports to standard paper questionnaires. The goal was to …

This completed study looked at whether a simple blood test (liquid biopsy) can help track breast, ovarian, and endometrial cancers. Researchers analyzed circulating tumor cells in 150 women to see if these cells could predict the risk of cancer spreading or how well treatment wor…

This completed study looked at a new antibody called anti-SIRPα as a potential immunotherapy for liver cancer. Researchers used blood and tissue samples from 30 liver cancer patients to see how the antibody affects immune cells. The goal was to understand whether blocking the SIR…

This study looked at two ways to help breast and ovarian cancer survivors get genetic counseling: a mailed brochure or a phone call with a health coach. About 668 women took part. The goal was to see which method led more people to actually get genetic counseling or testing. The …

This study looks at whether a score called KELIM can predict how well ovarian cancer patients respond to maintenance treatment with PARP inhibitors after initial chemotherapy. Researchers will analyze data from 243 patients who took part in the PAOLA-1 trial. If KELIM proves usef…

This study looks at the DNA of 100 children (and young adults up to age 17) who have cancer, along with the DNA of their healthy parents. The goal is to find genetic changes that may have caused the cancer. By comparing the child's DNA to both parents', researchers hope to discov…

This study tested whether letting patients move freely between the injection of a radioactive tracer and the PET scan affects image quality. Normally, patients must rest for an hour to avoid muscle uptake that can blur results. The trial involved 284 adults with cancer or needing…

This study looks at whether it's possible for people diagnosed with solid tumors to have a follow-up visit with their general practitioner within 15 days of learning their diagnosis. Researchers will track how many patients actually attend this visit and why some might not. The g…

This study followed 40 women with cervical, uterine, or ovarian cancer to see how their relationship and sexual communication changed from diagnosis to 3 months after treatment. Participants filled out questionnaires about their sexual activity, desire, and discomfort. The goal w…

This study looked at 1,500 women with advanced ovarian, peritoneal, or fallopian tube cancer to see how genetic changes in their tumors relate to how the disease progresses. Researchers collected tumor samples and medical data to find links between DNA abnormalities and outcomes …

This pilot study tested whether it's possible to adjust proton radiation plans each day while the patient is on the treatment table. Ten adults with solid tumors took part. The goal was to see if this approach is safe and practical enough to study in a larger trial.

This study measured how two common blood thinners (rivaroxaban and apixaban) behave in 193 adults with active cancer who also had blood clots or atrial fibrillation. Researchers aimed to understand factors like age, weight, and kidney function that affect drug levels. The goal wa…

This completed study at Sohag Oncology Center tested whether a quality-of-life survey could help match cancer patients' needs with the right supportive care, like pain management or nutrition counseling. Over 4,400 adult cancer patients completed the EORTC QLQ-C30 questionnaire, …

This study tested whether a two-hour, peer-led workshop with religious messages could encourage Muslim women in North East England and Scotland to get screened for breast, bowel, and cervical cancer. 169 women aged 25-74 who were not up-to-date with all eligible screenings took p…

This study looked at how doctors in Russia treat a specific type of ovarian cancer called HRD-positive. Researchers collected information from 414 patients to understand what treatments they received and how they fared. The goal was to describe real-world practice, not to test a …

Researchers tested a new online tool called PIPO that helps doctors estimate how long a cancer patient might live. This information can guide decisions about which patients to enroll in early-phase clinical trials. The study included 586 people who had already joined phase 1 or p…

This study tested a machine learning model that uses electronic health records to predict which cancer patients receiving infusion therapy are at risk of needing emergency care or hospitalization within 30 days. Researchers analyzed data from over 4,700 patients at UCSF. The goal…

This study looked at whether a special PET/CT scan, done within two months after treatment, helps doctors make better decisions for patients with advanced cervical cancer. Researchers compared what doctors would decide without the scan versus with it. The study involved 40 patien…

This pilot study tested a program called GUIDE, which uses a trained navigator to help cancer patients overcome social and financial barriers to joining clinical trials. The study included 100 adults with cancer who were eligible for a trial and had at least one health-related so…

This study created and tested an educational website to help Black and African American cancer patients learn about personalized cancer treatments and clinical trials. Researchers interviewed 48 patients and caregivers, then tested the website with 33 patients. The goal was to se…

This study tested a digital health platform to help people with a hereditary risk of breast and ovarian cancer share their genetic test results with family members. Researchers worked with 128 participants in Switzerland and Korea to see if the tool reduced distress and improved …

This study looked back at 388 women with advanced ovarian, fallopian tube, or peritoneal cancer who were taking the drug niraparib as maintenance therapy. Researchers wanted to see how often serious side effects happened and how patients used the drug in real-life UK clinics. No …

This study tested whether a special MRI scan (31P-MRS) can detect early signs of damage to heart and muscle cells caused by chemotherapy drugs like doxorubicin. Twelve cancer patients scheduled for chemo underwent three scans over time. The goal was to see if the scan could measu…

This study tested whether a family history app can help doctors collect and use information about patients' family health risks. Over 600 adults aged 30-69 took part. The goal was to see if the app leads to better screening and genetic referrals for conditions like cancer, heart …

This study reviewed over 11,000 patients with advanced ovarian cancer to see if hospitals that follow ten specific quality standards for surgery have better outcomes. The research looked at how long patients lived without their cancer getting worse and overall survival. The goal …

This completed study looked at how often joint pain occurs in 71 people with ovarian, colorectal, or lung cancer who were taking the drug bevacizumab. Participants filled out a questionnaire about their joint pain over 6 months. The goal was to better understand this side effect.

This study tested whether a flexible, personalized exercise program is practical for cancer patients receiving chemotherapy. Twenty-one adults with breast, ovarian, or colorectal cancer took part. The main goal was to see if patients would join, attend, and stick with the exercis…

This study follows over 1,700 women who previously took part in a cervical cancer screening trial. Researchers want to see if testing for HPV alone is as safe and effective as combining it with a Pap smear over 10 years. Participants provide a cervical sample for both tests, and …

This study looked at how cancer patients feel about returning to work while undergoing treatment. Researchers interviewed 20 patients to understand their needs and how work affects their sense of normalcy. The goal is to help nurses provide better support for work-related challen…

This study looked at whether analyzing the DNA of a patient's tumor can help doctors pick a targeted therapy for advanced or metastatic cancer. Researchers enrolled 550 adults with various solid tumors that had spread. They took biopsy or blood samples to search for genetic chang…

This study looked at 135 people with advanced lung cancer, lymphoma, or other tumors treated with immunotherapy drugs called checkpoint inhibitors. Researchers collected blood and tumor samples over time to measure immune cells and molecules that might predict whether the treatme…

This study tested a tool built into electronic health records that prompts doctors to discuss heart health with cancer survivors during routine visits. Researchers enrolled 645 survivors of breast, prostate, colorectal, endometrial, and lymphoma cancers across 12 clinics. The goa…

This study tested two different PET-CT scanners to see which one is better at finding very small cancer spots (less than 1 cm) in patients. Twenty-four people with cancer each had two scans, one on each machine. The researchers then added virtual lesions to the images to compare …

This study looked at whether following national guidelines for ovarian cancer surgery is cost-effective. Researchers measured the cost per quality-adjusted life year (QALY) over three years in 200 women with advanced ovarian cancer. The goal was to understand the economic impact …

This completed study tested whether a new biomarker called 'mass response' can predict how well a cancer therapy will work. Researchers collected tumor cells from 72 patients with various cancers through fluid drainage or biopsies. The goal was to see if this biomarker could guid…

This completed study looked at 300 cancer patients treated with immune checkpoint inhibitors to see if measuring troponin levels could help detect serious heart problems early. The goal was to prevent major cardiovascular events like heart attack or stroke without unnecessarily s…

This study looked at how immune checkpoint inhibitors, a type of cancer drug, might affect blood vessels and increase heart risks. Researchers measured blood vessel function and checked for related markers in 39 cancer patients before and after starting treatment. The goal was to…

This completed study tested a new tool called Life S-Can that quickly checks diet, exercise, sleep, and mental health in cancer survivors. 105 survivors used the tool and some received extra coaching from health experts. The goal was to see if the tool helps doctors give better s…

This study looked at 22 women with cervical cancer to see if having an empty bladder (using a catheter) or a full bladder (filled with 120cc of fluid) is better during a type of internal radiation called brachytherapy. The goal was to find which method lowers the radiation dose t…

This study tested whether having a clinical pharmacist review medications for cancer patients before they start treatment could prevent drug-related problems. Researchers observed 440 adults with solid tumors who were about to receive chemotherapy, immunotherapy, or oral targeted…

This study gathered information from nearly 3,000 cancer patients aged 65 and older to learn more about their health, living situations, and the care they receive. No new treatments were tested. The goal was to create a database that helps doctors and researchers better understan…

This study looked at how often a muscle enzyme called CPK increases in people with solid tumors who are taking a type of targeted therapy called tyrosine kinase inhibitors (TKIs). Researchers measured CPK levels in routine blood tests from 154 patients and checked if high levels …

This study looked at how common frailty is in people aged 70 and older with solid tumors who visited a cancer center. Researchers used a short questionnaire called VES-13 to screen patients before their doctor visit. They also compared the test results with the doctor's own judgm…

This study looked at 386 women with cervical, uterine, or ovarian cancer to compare standard laparoscopic surgery versus robot-assisted laparoscopic surgery. The goal was to see which approach causes fewer complications within six months after the operation. Researchers tracked s…

This study explores whether using a PET-scan at the start of brachytherapy (internal radiation) is feasible for patients with locally advanced cervical cancer. Fourteen participants who have already received chemoradiation will undergo an extra PET-scan during brachytherapy and a…

This study compared anxiety, depression, and quality of life between 125 cancer patients who joined clinical trials and those who received standard treatment. Researchers used questionnaires to measure stress and emotional well-being. The goal was to understand how trial particip…

This study looked at how patients with advanced cancer respond to being offered a conversation about their future care preferences. Researchers invited 71 patients to discuss their wishes and tracked who took part. The goal was to learn more about what helps patients feel ready t…

This study tested a digital chatbot (called CATALYST) to help cancer survivors learn about genetic testing for inherited cancer risk. Fifty adults who had certain cancers (like breast, ovarian, or prostate) used the chatbot or received usual care. The goal was to see if the chatb…

This study tested whether a special survivorship clinic, combined with an app for reporting symptoms, is practical for women who have finished curative treatment for early-stage breast, cervical, or endometrial cancer. Two hundred women visited the clinic at the start and end of …

This study tested a program called FinFit to help adolescent and young adult cancer survivors deal with money problems caused by their illness. Researchers interviewed 16 people from community cancer clinics to design and improve the program. The goal was to figure out the best w…

This study watched 225 people with solid tumors who got a drug called G-CSF during chemotherapy. G-CSF can cause bone pain. Researchers measured pain levels and tracked what treatments (like pain relievers or other methods) helped. They also checked quality of life, fatigue, mood…

This study looked at how financial problems affect the well-being of hospitalized cancer patients and their caregivers in Turkey. Over 750 patients filled out surveys about their finances, mood, and quality of life. The goal was to understand the link between money stress and car…

This study looked at 3820 adults with cancer who also had COVID-19. Researchers collected routine medical data to describe symptoms and identify factors affecting survival. The goal was to learn more about how COVID-19 affects cancer patients, not to test a new treatment.

This study looked at whether using a Spiritual Needs Questionnaire helps identify and address the spiritual needs of patients in palliative care. About 100 patients with cancer, heart failure, COPD, or ALS took part. The goal was to see if this approach is practical and beneficia…

This study tested whether showing cancer survivors real-time glucose data from a wearable sensor can encourage them to be more physically active. 60 cancer survivors at high risk for type 2 diabetes wore a Fitbit and some also wore a continuous glucose monitor for 4 weeks, receiv…

This study looked at how behavioral factors, hormones, and natural body chemicals might influence tumor growth in ovarian cancer. Researchers studied 613 women with ovarian cancer to understand these connections. The goal was to gather knowledge, not to test a treatment.

This study looked at whether giving women a self-collection kit for HPV testing at their family doctor's office would encourage more women to get screened for cervical cancer. The study involved 308 women aged 30-65 who were overdue for screening. Some women were offered the usua…

This study looked at 103 diabetic adults starting chemotherapy for cancer. Researchers used a continuous glucose monitor (Freestyle Libre) to track blood sugar changes. The goal was to see how often blood sugar went too low or too high during treatment, since chemotherapy and rel…

This completed study looked at how often fallopian tubes are completely removed when women have surgery to remove an ovary and tube (adnexectomy). The goal was to improve the surgical technique to lower the risk of ovarian cancer. 115 women participated, and researchers checked f…

This study looked at 33 adults who had both immune thrombocytopenia (ITP) — a condition where the immune system destroys platelets — and cancer. Researchers wanted to see if treating the cancer could also improve ITP. They also investigated whether cancer cells might mimic platel…

This study tested a web-based program called GIFT that helps cancer patients share information about inherited cancer risks with their relatives. Over 3,000 patients and their family members took part. The goal was to see if the tool encourages more relatives to get genetic testi…

This study looked at whether measuring elastin fragments in blood or urine can help assess frailty in people aged 65 and older with cancer. Frailty is hard to measure with current methods, which can be slow and subjective. The researchers hope that a biological marker could provi…

This study looked at whether sending reminders to cancer patients and alerts to their nurses helps them complete regular symptom questionnaires. Over 476 patients starting a new cancer therapy were split into three groups: usual care, reminders plus nurse alerts during clinic vis…

This study analyzed 2000 women who had surgery for endometriosis to see if the lesions tend to appear more on the right or left side of the pelvis. By carefully recording the location of each lesion during surgery, researchers hope to learn more about how endometriosis develops. …

This study looked at two methods to help women who have not been screened for cervical cancer get tested. One group received a vaginal self-sampling kit in the mail, while the other was invited to visit their general practitioner. The goal was to see which approach leads more wom…

This study looked at how well the Pfizer COVID-19 vaccine triggers an immune response in 196 adults with weakened immune systems (due to conditions like kidney transplant, cancer, or HIV) compared to healthy adults. Researchers measured antibody levels and their ability to neutra…

This completed study looked at how muscle energy use differs in women with ovarian or endometrial cancer who are losing weight, depending on their body mass index (BMI). Researchers took blood samples, muscle biopsies, and fat tissue from 70 women during surgery. The goal was to …

This study looked at how chemotherapy impacts the quality of life of women treated for stage II or III endometrial cancer. Researchers asked 51 patients to fill out questionnaires about their physical, emotional, and social well-being at least two years after finishing treatment.…

This study looked at 267 women with early-stage cervical cancer to compare two surgical approaches: removing all pelvic lymph nodes versus removing only the sentinel (first) lymph node. The goal was to see which method causes fewer complications within 6 months after surgery. Res…

This study tracked 300 cancer patients receiving their first round of chemotherapy to see how often nausea and vomiting still happen, even with standard anti-nausea medicines. Participants filled out questionnaires about their symptoms in the first 24 hours and up to 4 days after…

This study looked at how women feel and think after getting a personalized estimate of their breast cancer risk. Researchers used a special computer model (BOADICEA) to give each woman a risk score based on her genes. The goal was to see if this personalized information changes h…

This study tested whether an automated system can grow cancer cells from patient samples (blood, fluid, or tumor tissue) inside chicken eggs. Researchers aimed to see if at least half of the samples would successfully grow. The goal is to create a better, cheaper way to study can…

This study looked at health-risk behaviors like smoking, alcohol use, diet, and exercise among 46 cancer survivors in France. The goal was to see how common these behaviors are so doctors can better help survivors avoid future health problems. The study found that many survivors …

This study looked at medical records from 509 adults in Taiwan to find out how often advanced cervical, endometrial, and ovarian cancers have a specific marker called HER2 IHC 3+. Researchers also described the patients' health details to better understand who might benefit from …

This study tested whether showing patients videos about advance care planning and training doctors in communication skills helps cancer patients document their care wishes. Over 13,000 patients from multiple clinics took part, with most only having their medical records reviewed.…

This study tested a questionnaire called PO-BADO that helps doctors and nurses talk with cancer patients and their caregivers. Researchers checked if the questionnaire gives consistent and reliable results. 252 adults with cancer who have a caregiver support time took part. The g…

This study brought together experts to decide what health outcomes matter most when testing cancer treatments in older adults. Instead of focusing only on tumor shrinkage, they identified key areas like independence, memory, mood, and nutrition. The goal is to help future clinica…

This study tested over 1,000 women with endometrial cancer for DNA repair problems that can be inherited (Lynch syndrome). By analyzing tumor DNA, researchers aimed to personalize cancer treatment and identify family members who might also be at risk. The goal was to improve care…

This study followed 76 cancer patients over age 70 to see how geriatric tests and social factors affect their quality of life. Researchers wanted to learn how to better tailor chemotherapy and care for older adults. The goal was to improve both well-being and cost-effectiveness o…

This study looked at 700 cancer patients to understand how often dangerous blood clots occur and how blood-thinning medications affect them. Researchers tracked patients over two years, analyzing blood samples and clotting events. The goal is to improve prevention and treatment o…

This study looked at whether having cancer patients report their own symptoms during radiation treatment helps doctors notice and manage side effects better. About 104 adults with lung, esophageal, or other gastrointestinal cancers took part. Doctors reviewed patient-reported sym…

This study looked back at medical records of 342 women in Europe with advanced ovarian cancer and a BRCA gene mutation. All had taken the drug olaparib (Lynparza) as their first maintenance treatment after initial chemotherapy. Researchers tracked how long patients lived without …

This completed study looked at 12,500 cancer patients who had a type of heart attack called NSTEMI. Researchers compared those who got invasive procedures like angiography versus those treated only with medications. The goal was to see which approach led to fewer deaths in the ho…

This study followed 153 people with cancer who had or were suspected of having COVID-19. Researchers collected throat swabs and saliva samples over several weeks to see how well antibody and antigen tests work in this group. The goal was to learn more about the course of COVID-19…

This study followed 102 women with ovarian, fallopian tube, or endometrial cancer through six cycles of standard chemotherapy (carboplatin and paclitaxel). Researchers measured taste changes, muscle loss, and nutritional decline at the start, halfway, and end of treatment. The go…