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New drug ZGGS15 tested in patients with advanced cancers

NCT ID NCT05864573

First seen Jan 11, 2026 · Last updated Jun 22, 2026 · Updated 26 times

Summary

This early-stage trial tested a new biologic drug called ZGGS15 in 22 adults with advanced solid tumors who had no standard treatment options left. The main goals were to check safety, find the right dose, and look for early signs that the drug might control tumor growth. Participants received the drug by IV infusion once every three weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Zhejiang Cancer Hospital

    Hangzhou, Zhejiang, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ZGGS15 (a biologic drug given by IV infusion)

What this could lead to

If successful, this could lead to a new treatment option for people with advanced solid tumors who have run out of standard therapies.

What could go wrong

This is a very early Phase 1 trial with only 22 participants, so it is primarily testing safety and dosing. The drug may not shrink tumors or may cause side effects.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.