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Could a chemo pill boost immunotherapy for tough cancers?

NCT ID NCT05276284

First seen Jan 15, 2026 · Last updated May 23, 2026 · Updated 19 times

Summary

This early-phase trial tested whether adding thiopurine drugs (6-MP and 6-TG) to the immunotherapy atezolizumab could help shrink advanced solid tumors that have a moderate number of genetic mutations. The study enrolled 18 adults with metastatic cancers that had no standard cure. Researchers measured safety, side effects, and tumor response to find the best dose and see if the combination was effective.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University Hospital of Copenhagen, Rigshospitalet

    Copenhagen, 2100, Denmark

Conditions

Explore the condition pages connected to this study.