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Can a Child's cancer be inherited? new study digs into family DNA

NCT ID NCT04471961

Knowledge-focused Sponsor: University Hospital, Montpellier Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at the DNA of 100 children (and young adults up to age 17) who have cancer, along with the DNA of their healthy parents. The goal is to find genetic changes that may have caused the cancer. By comparing the child's DNA to both parents', researchers hope to discover new inherited risk factors and better understand why some children develop cancer.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

100 people

The number who actually took part.

Started

Jul 2020

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * The patient has a solid or haematological malignancy, either familial forms or isolated cases diagnosed between the ages of 0 and 17 years. * The minor patient and both biological parents are available to participate in the study OR * The adult patient and one or both parents are available to participate in the study. * The patient's parents must have given their free and informed consent and signed the consent for the minor's participation in the study. * The patient's parent(s) must have given free and informed consent and the patient of legal age must have signed the consent for participation in the study. * The patient must be affiliated or beneficiary of a Frrench social security scheme. Exclusion Criteria: * The patient's parents are under guardianship or trusteeship or under legal protection Yes No * Failure to obtain written informed consent from parents (for themselves and their minor child) after a period of reflection Yes No * No affiliation to or beneficiary of a French social security scheme (for biological parents and the patient)

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Conditions

The condition(s) this trial relates to.

childhood leukemia childhood neoplasm hematopoietic and lymphoid cell neoplasm hematopoietic and lymphoid system neoplasm hereditary neoplastic syndrome neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Familial cancer Hematological tumor Pediatric tumor Solid tumor, childhood

Contacts and locations

Locations

  • CHU Montpellier

    Montpellier, Occitanie, 34295, France

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