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Peppermint and lemon scents put to the test against chemo nausea

NCT ID NCT04560114

Symptom relief Sponsor: Centre Francois Baclesse Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 17, 2026 · Last updated Aug 18, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether inhaling a blend of peppermint and lemon essential oils can reduce nausea and vomiting in people receiving their first chemotherapy for a solid tumor. Participants will inhale the oils four times daily and whenever nausea strikes, with symptoms tracked over the first days after treatment. The study aims to measure how well this natural approach works as a supportive care option.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Inhaled blend of peppermint and lemon essential oils
What this could lead to
If effective, this could offer a safe, natural option to help reduce nausea and vomiting during chemotherapy, improving quality of life for cancer patients.
What could go wrong
This is an early-phase study without a placebo comparison, so results may be inconclusive. Effectiveness is not yet proven, and individual responses to aromatherapy can vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

96 people

The number who actually took part.

Started

Dec 2020

Finished

Jun 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Patients will be eligible if: * Aged over 18, * Presenting a solid tumor in the 1st line of chemotherapy administered by intravenous route; * Treated with adjuvant or neoadjuvant chemotherapy; * Affiliated with a social security scheme; * Able to understand the meaning of the questions asked; * Having given their written consent to participate in the study; * Whether or not treated with surgery and radiotherapy before entering the study Exclusion Criteria: Patients who: * Do not give their consent to participate; * Do not master the French language; * Are deprived of their liberty, under guardianship or curatorship; * Suffer from cognitive deficits or associated psychiatric disorders that could compromise their ability to participate in the study (eg: schizophrenia); * Are undergoing radiotherapy; * Must receive a combination of radio-chemotherapy; * Whose chemotherapy protocol is composed of several chemotherapy administrations per week during a course of treatment; * have been previously treated with chemotherapy; * Have an occlusive syndrome; * Have primary cancer of the central nervous system or brain metastases; * Have cancer of the Upper Aero Digestive Tract; * Simultaneously participate in a therapeutic clinical trial; * Have an intolerance to a component of essential oils; * Pregnant or breastfeeding.

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Conditions

The condition(s) this trial relates to.

Nausea neoplasm Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aromatherapy Essential oil Nausea and vomiting Suportive care

Contacts and locations

Locations

  • Centre Francois Baclesse

    Caen, 14000, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.