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Lower dose of olanzapine may ease chemo nausea with less drowsiness

NCT ID NCT07403370

First seen Feb 24, 2026 · Last updated Jun 16, 2026 · Updated 17 times

Summary

This study looked at 2,000 adults with solid tumors to find the best dose of olanzapine for preventing nausea and vomiting caused by strong chemotherapy. Researchers compared 2.5 mg, 5 mg, and 10 mg doses to see which works best with the fewest side effects like daytime sleepiness. The goal is to improve comfort during cancer treatment.

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Contacts and locations

Locations

  • Department of Medical Oncology

    Jinan, Shandong, China

Conditions

The condition(s) this trial relates to.

Nausea neoplasm Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.