ADVANCED SOLID TUMORS
Clinical trials for ADVANCED SOLID TUMORS explained in plain language.
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New hope drug enters human testing for Tough-to-Treat cancers
Disease control Recruiting nowThis early-stage clinical trial is testing a new drug called VIB305 in people with advanced solid tumors that have stopped responding to standard treatments. The study aims to find the safest and most effective dose and to see if the drug can help control the cancer. It will enro…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Vibrant Sciences Limited • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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New cancer drug targets specific protein in advanced tumors
Disease control Recruiting nowThis is the first human study of an experimental drug called ASP1002 for people with advanced solid tumors that have spread. The main goals are to find a safe dose and check for side effects. The study will enroll adults whose cancers have high levels of a protein called claudin-…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Astellas Pharma Global Development, Inc. • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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New cancer drug begins first human testing
Disease control Recruiting nowThis is the first human study of an experimental drug called BTM-3566 for adults with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find safe dose levels and see how the drug behaves in the body. Participants will take the drug i…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Bantam Pharmaceuticals • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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New drug duo enters human testing for Tough-to-Treat cancers
Disease control Recruiting nowThis study is testing the safety and initial effectiveness of a new two-drug combination (YL201 plus ivonescimab) for people with advanced solid tumors, including specific types of lung cancer. The main goals are to find the safest dose and see if the treatment can shrink tumors.…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd. • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Experimental cancer drug enters first human trials for multiple advanced cancers
Disease control Recruiting nowThis is the first human study of an experimental cancer drug called M7437, designed to target specific proteins found on cancer cells. The trial aims to find a safe dose and see if the drug shows early signs of effectiveness in people with advanced solid tumors that have stopped …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: EMD Serono Research & Development Institute, Inc. • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New cancer drug enters human testing for Tough-to-Treat tumors
Disease control Recruiting nowThis early-stage study aims to find a safe and effective dose of a new drug called EIK1005 for people with advanced solid tumors that have spread or cannot be removed by surgery. Researchers will test EIK1005 by itself and combined with an existing immunotherapy drug (pembrolizum…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Eikon Therapeutics • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New cancer drug enters human testing for advanced tumors
Disease control Recruiting nowThis is an early-stage study to test the safety and side effects of a new drug called MK-0472 for people with advanced or metastatic solid tumors. Researchers will give the drug alone and in combination with other cancer therapies to about 178 participants. The main goal is to fi…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Radioactive drug trial offers new hope for advanced cancer patients
Disease control Recruiting nowThis early-stage trial is testing a new radioactive drug called HRS-6768 in patients with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find a safe and effective dose and to see how the drug moves through and affects the body. Re…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Jiangsu HengRui Medicine Co., Ltd. • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New drug targets 'Undruggable' cancer mutation in major trial
Disease control Recruiting nowThis clinical trial is testing an experimental drug called GFH375 for people with advanced solid tumors that have a specific genetic mutation called KRAS G12D. The study aims to determine if the drug is safe, how it moves through the body, and if it can help shrink tumors. It wil…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Genfleet Therapeutics (Shanghai) Inc. • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New cancer drug trial seeks to control advanced tumors
Disease control Recruiting nowThis study is testing a new drug called MK-3120 in people with advanced solid tumors that have spread and cannot be removed by surgery. The main goals are to check if the drug is safe and if people can tolerate it, while also seeing if it helps shrink tumors or slow cancer growth…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New Two-Pronged attack on advanced cancers enters human testing
Disease control Recruiting nowThis study is testing a new investigational drug called marlotamig, both by itself and in combination with an existing immunotherapy drug (cemiplimab), for people with advanced solid tumors. The main goals are to find a safe and effective dose and to see how well the treatments w…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New cancer drug enters human testing for Tough-to-Treat tumors
Disease control Recruiting nowThis early-stage trial is testing a new drug called TEV-56278, both alone and combined with an existing immunotherapy (pembrolizumab), for people with advanced solid tumors that have stopped responding to standard treatments. The study aims to find safe doses and see if the drug …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Teva Branded Pharmaceutical Products R&D, Inc. • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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First human trial launches for experimental cancer therapy
Disease control Recruiting nowThis is an early-stage study to test the safety and find the right dose of a new drug called ABX-001. It will be given to adults with advanced solid tumors that have stopped responding to standard treatments. The study will test the drug by itself and also in combination with an …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Abalos Therapeutics GmbH • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Radioactive cancer drug enters first human tests
Disease control Recruiting nowThis is a very early study to test the safety and find the right dose of a new radioactive drug called 177Lu-RAD202 for people with advanced HER2-positive solid tumors. The study will enroll about 30 adults whose cancer has progressed after standard treatments. First, a small 'im…
Matched conditions: ADVANCED SOLID TUMORS
Phase: EARLY_PHASE1 • Sponsor: Radiopharm Theranostics, Ltd • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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New cancer drug enters human testing for advanced tumors
Disease control Recruiting nowThis is the first human trial of a new cancer drug called BMS-986484. Researchers are testing it alone and combined with an existing immunotherapy (nivolumab) in 213 people with advanced solid tumors, including lung, pancreatic, and colorectal cancers. The main goal is to find sa…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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New hope for tough cancers: first human test of experimental drug begins
Disease control Recruiting nowThis is the first study in humans of an experimental drug called MGC028 for people with advanced solid tumors that have stopped responding to standard treatments. Researchers will test increasing doses in about 124 participants to find the highest safe amount and check for side e…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: MacroGenics • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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New experimental drug targets advanced cancers with specific marker
Disease control Recruiting nowThis early-stage study is testing an experimental drug called SHR-A1904 in people with advanced solid tumors, specifically gastric, pancreatic, and other cancers that have stopped responding to standard treatments. The main goals are to find the safest and most effective dose, ch…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Jiangsu HengRui Medicine Co., Ltd. • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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New oral pill targets common Cancer-Causing mutations in major trial
Disease control Recruiting nowThis study is testing a new oral medication called RMC-6236 in adults with advanced solid tumors, including lung, colorectal, and pancreatic cancers, that have specific RAS mutations. The main goals are to find a safe and effective dose and to see if the drug can help control the…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Revolution Medicines, Inc. • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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New cancer drug enters first human trials for Tough-to-Treat tumors
Disease control Recruiting nowThis is a first-in-human study to test the safety and find the right dose of a new drug called FS-8002 in people with advanced solid tumors. It will enroll 66 patients whose cancer has progressed despite standard treatments. The main goal is to see how much of the drug the body c…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Shanghai Pushi Medical Science Co. Ltd • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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First patients to test new cancer drug in global trial
Disease control Recruiting nowThis is the first time a new drug called GenSci139 is being tested in people. The study aims to find a safe dose and see how the body processes the drug in patients with advanced solid tumors that have spread or cannot be removed by surgery. Researchers will also look for early s…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Changchun GeneScience Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Scientists test supercharged immune cells against tough cancers
Disease control Recruiting nowThis study is testing a new type of cell therapy for people with advanced solid tumors that have not responded to standard treatments. Doctors take a patient's own immune cells from a tumor sample, modify them in the lab to potentially work better, and then infuse them back into …
Matched conditions: ADVANCED SOLID TUMORS
Phase: EARLY_PHASE1 • Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New cancer drug enters human testing for advanced tumors
Disease control Recruiting nowThis is the first human study of an experimental cancer drug called SKB500. Researchers want to find out if it's safe, how the body processes it, and if it shows any signs of fighting cancer. The study will enroll 180 adults with advanced solid tumors that haven't responded to st…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New hope for tough cancers: testing Triple-Threat drug combos
Disease control Recruiting nowThis study is testing new combinations of experimental drugs for people with advanced solid tumors that have specific RAS mutations. Researchers want to see if combining a new type of drug called a RAS(ON) inhibitor with another cancer drug called ivonescimab is safe and can help…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Revolution Medicines, Inc. • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New cancer drug begins first human testing
Disease control Recruiting nowThis is the first study in people to test a new drug called SKB445 for patients with advanced solid tumors that have not responded to standard treatments. The main goals are to find a safe dose and see how the body processes the drug. Researchers will also look for early signs th…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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First human trial launches for promising new cancer pill
Disease control Recruiting nowThis is a first-in-human study to test the safety and early effectiveness of a new oral drug called VVD-133214. It will be given alone and in combination with an existing immunotherapy (pembrolizumab) to people with advanced solid tumors that have specific genetic features known …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Vividion Therapeutics, Inc. • Aim: Disease control
Last updated Mar 31, 2026 12:10 UTC
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New pill targets cancer cell machinery in First-Ever human trial
Disease control Recruiting nowThis is the first study in people to test a new oral drug called ATX-295, which works by blocking a specific protein that helps cancer cells divide. The main goals are to find a safe dose and see how the body processes the drug in about 90 patients with advanced solid tumors, inc…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Accent Therapeutics • Aim: Disease control
Last updated Mar 31, 2026 12:10 UTC
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New hope for tough cancers: first human trial of experimental drug begins
Disease control Recruiting nowThis is the first time researchers are testing the experimental drug SKB518 in people. The study aims to find a safe dose and see how the body handles the drug in 150 adults with advanced solid tumors that have stopped responding to standard treatments. The main goal is to check …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New drug combo trial targets advanced cancers with specific mutation
Disease control Recruiting nowThis early-stage trial is testing whether a new drug called HRS-4642, when combined with other cancer treatments, is safe and effective for people with advanced solid tumors that have a specific genetic change (KRAS G12D mutation). The study aims to find the best dose and see if …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Jiangsu HengRui Medicine Co., Ltd. • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Engineered virus teams up with immune drug to fight tough cancers
Disease control Recruiting nowThis study is testing a new two-part treatment for advanced solid tumors that have not responded to standard therapies. It combines a specially engineered virus designed to attack cancer cells with a drug that helps the immune system fight cancer. The main goals are to see if thi…
Matched conditions: ADVANCED SOLID TUMORS
Phase: NA • Sponsor: Hangzhou Converd Co., Ltd. • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New cancer drug combo enters human testing
Disease control Recruiting nowThis early-stage study is testing the safety and initial effects of a new drug called SYN818 when given with an existing cancer drug, olaparib. It is for adults with advanced or metastatic solid tumors (like ovarian or breast cancer) that have specific genetic changes (BRCA mutat…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Hangzhou SynRx Therapeutics Biomedical Technology Co., Ltd • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New cancer drug combo trial seeks to control advanced tumors
Disease control Recruiting nowThis study is testing a new drug called SHR-1826, given alongside other cancer treatments, for people with advanced solid tumors. The main goals are to find a safe dose, see how well the body tolerates it, and measure if it helps shrink tumors. Researchers will enroll about 876 a…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Suzhou Suncadia Biopharmaceuticals Co., Ltd. • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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First patients to receive new experimental cancer drug
Disease control Recruiting nowThis is the first study in people to test a new potential cancer drug called BG-C477. The main goal is to find out if the drug is safe, what side effects it causes, and what dose to use. It will be tested alone and combined with other cancer treatments in adults with advanced sol…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: BeOne Medicines • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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New hope for advanced cancer patients after standard treatments fail
Disease control Recruiting nowThis is the first human study of an experimental drug called CKD-512. It aims to find a safe dose and see if the drug, given alone or with an existing immunotherapy (pembrolizumab), can help control advanced solid tumors. The study is for people whose cancer has continued to grow…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Chong Kun Dang Pharmaceutical • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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New cancer drug enters first human trials for Tough-to-Treat tumors
Disease control Recruiting nowThis is the first study in people to test an experimental drug called SIM0505 for advanced solid tumors. It aims to find a safe dose and see early signs of whether the drug can shrink tumors. The study is for adults with specific advanced cancers, like certain ovarian, kidney, ut…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: NextCure, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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New hope for advanced cancer patients in First-Ever drug trial
Disease control Recruiting nowThis is the first time a new drug called ALK201 is being tested in people. The study aims to find a safe dose and see if it can help shrink tumors in adults with advanced solid cancers that have spread. Researchers will also check how the drug moves through the body and look for …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Shanghai Allink Biotherapeutics Co., Ltd. • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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New targeted cancer drug enters human testing
Disease control Recruiting nowThis early-stage study is testing a new drug called YL205 in people with advanced solid tumors that have spread or cannot be removed by surgery. The main goals are to find a safe dose, see how the body processes the drug, and get a first look at whether it helps shrink tumors. Th…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd. • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Scientists test re-engineered immune cells to fight advanced cancers
Disease control Recruiting nowThis early-phase study is testing the safety and effectiveness of a personalized immune cell therapy for adults with advanced solid tumors that have not responded to standard treatments. Doctors take a patient's own tumor-fighting immune cells, grow large numbers of them in a lab…
Matched conditions: ADVANCED SOLID TUMORS
Phase: EARLY_PHASE1 • Sponsor: Shanghai Juncell Therapeutics • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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New pill aims to reawaken immune system to fight advanced cancers
Disease control Recruiting nowThis early-stage study is testing a new oral drug called ASP1570 in adults with advanced solid tumors that have spread or cannot be removed by surgery. The main goals are to find a safe dose and see how well the drug is tolerated, both by itself and when combined with other stand…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Astellas Pharma Global Development, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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First patients to receive new experimental cancer pill
Disease control Recruiting nowThis is the first study in people to test a new oral drug called VVD-159642, which is designed to block specific cancer growth signals. It will enroll about 220 adults with advanced solid tumors that have spread or cannot be removed by surgery. The main goals are to find a safe d…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Vividion Therapeutics, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New hope drug tested for patients out of treatment options
Disease control Recruiting nowThis is an early-stage study testing a new drug called Hemay181 in patients with advanced solid tumors that have stopped responding to standard treatments. The main goals are to see if the drug is safe and if it can shrink tumors. The study will enroll about 24 patients who have …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Ganzhou Hemay Pharmaceutical Co., Ltd • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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New drug trial offers hope for advanced cancer patients
Disease control Recruiting nowThis early-stage study is testing a new drug called GW5282 in adults with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find a safe dose and see if the drug can shrink tumors. Researchers will first test increasing doses to check…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Dizal Pharmaceuticals • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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First patients to test new hope for Tough-to-Treat cancers
Disease control Recruiting nowThis is the first study in people to test a new drug called GenSci143 for advanced solid tumors. The main goals are to find a safe dose and see how the body processes the drug. It is for adults whose cancer has continued to grow despite standard treatments or who have no other tr…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Changchun GeneScience Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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New cancer drug begins human testing for Tough-to-Treat tumors
Disease control Recruiting nowThis is the first study in people testing a new drug called PHST001 for adults with advanced solid tumors that have returned or stopped responding to all available standard treatments. The main goals are to find a safe dose and see how the body handles the drug. Researchers will …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Pheast Therapeutics • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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New hope for advanced cancer patients in major drug trial
Disease control Recruiting nowThis study is testing a new drug called BMS-986482 to see if it is safe and effective for treating advanced solid tumors. It will involve about 413 adults whose cancer has progressed despite standard treatments. The drug will be tested both by itself and in combination with other…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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New Triple-Threat cancer treatment enters first human safety tests
Disease control Recruiting nowThis is an early safety study to see if a new drug called AT1019 is safe when given with targeted radiation and an immunotherapy drug for people with advanced solid tumors. The main goal is to find the highest dose of AT1019 that patients can tolerate without severe side effects.…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: The Affiliated Hospital of Xuzhou Medical University • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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New oral cancer drug enters first human safety testing
Disease control Recruiting nowThis is the first study in humans testing PAS-004, an oral medication designed to target specific genetic mutations found in advanced solid tumors. The main goal is to find a safe dose and understand side effects in 48 adults whose cancers have progressed despite standard treatme…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Pasithea Therapeutics Corp. • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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New hope for tough cancers: early trial tests novel therapy
Disease control Recruiting nowThis study is testing a new drug called MB0151 in adults with advanced solid tumors that have progressed after standard treatments. The main goals are to find a safe dose and see if the drug can shrink or control tumors. The trial is open to people with specific cancers, includin…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Mainline Biosciences (Shanghai) Co., Ltd • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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New-Generation cancer pill aims for fewer side effects, targets brain tumors
Disease control Recruiting nowThis study is testing a new oral drug called SPR1020 in adults with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find a safe dose and see how the body processes the drug. Researchers hope this new, more targeted drug may shrink …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Shanghai SciBrunch Therapeutics Co., Ltd. • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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New drug trial targets 'Undruggable' cancer mutation
Disease control Recruiting nowThis early-stage study is testing a new drug called RMC-5127 in adults with advanced cancers that have a specific genetic change called KRAS G12V. The main goals are to find a safe dose and see how the body processes the drug, both when given alone and when combined with other ca…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Revolution Medicines, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New Two-Drug combo trial offers hope for Tough-to-Treat cancers
Disease control Recruiting nowThis study is testing whether a new drug called SPH4336 works better alone or when combined with another drug, cadonilimab, for people with advanced solid tumors that can't be removed by surgery. The main goal is to see if the treatment can slow or stop cancer growth and is safe …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Shanghai Pharmaceuticals Holding Co., Ltd • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New hope for advanced cancer patients as experimental drug enters human trials
Disease control Recruiting nowThis is the first study in humans of a new drug called INCA33890 for people with advanced or spreading solid tumors. Researchers will test different doses in 408 participants to find the safest amount and see how the body processes the drug. The main goals are to understand side …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Incyte Corporation • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New cancer pill begins first human tests in china
Disease control Recruiting nowThis is an early-stage study to test the safety and find the right dose of a new oral drug called ZX-8177. It will involve about 80 Chinese adults with advanced solid tumors that have not responded to standard treatments. The main goals are to see how the body handles the drug an…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Nanjing Zenshine Pharmaceuticals • Aim: Disease control
Last updated Mar 30, 2026 14:27 UTC
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New cancer drug enters human testing: could it control advanced tumors?
Disease control Recruiting nowThis early-stage clinical trial is testing a new drug called MRG006A in people with advanced solid tumors that have stopped responding to standard treatments. The study aims to find the safest and most effective dose and see if the drug can help shrink tumors. Researchers will en…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Lepu Biopharma Co., Ltd. • Aim: Disease control
Last updated Mar 27, 2026 12:41 UTC
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Groundbreaking cancer drug enters first human trials
Disease control Recruiting nowThis is the first study in humans testing a new cancer drug called TGW101. Researchers will give the drug to 50 patients with advanced solid tumors to check if it's safe and to find the right dose. They'll also look for early signs that the drug might help shrink tumors in cancer…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Tagworks Pharmaceuticals BV • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New cancer drug enters human testing for advanced tumors
Disease control Recruiting nowThis is the first human study of a new drug called HS-20122 for people with advanced solid tumors that have stopped responding to standard treatments. Researchers will test different doses to find the safest amount and see how the drug moves through the body. The study will also …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Hansoh BioMedical R&D Company • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New drug combo trial seeks to control advanced cancers
Disease control Recruiting nowThis study is testing a new drug called YL202, given alongside other cancer treatments, to see if it is safe and effective for people with advanced solid tumors like breast or lung cancer. The main goals are to find the safest dose and see if the treatment helps shrink tumors. It…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd. • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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First test of new precision drug targets Cancer's genetic weakness
Disease control Recruiting nowThis is the first study in people for a new drug called OKI-219, designed to target a specific genetic mutation (PI3KαH1047R) found in some advanced cancers. The main goals are to find a safe dose and see how the body handles the drug, both alone and combined with other cancer tr…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: OnKure, Inc. • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Experimental cell therapy tested on patients out of options
Disease control Recruiting nowThis early-stage study is testing the safety and initial effects of an experimental cell therapy called GK01 in patients with advanced lung or esophageal cancer who have no other treatment options left. Researchers will give GK01 to 10 patients and closely monitor for side effect…
Matched conditions: ADVANCED SOLID TUMORS
Phase: EARLY_PHASE1 • Sponsor: Beijing Geekgene Technology Co., LTD • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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New cancer drug begins first human testing
Disease control Recruiting nowThis study is testing a new drug called SHR-3821 in people with advanced solid tumors to see if it's safe and how the body processes it. Researchers will enroll 162 adults with various advanced cancers to determine the right dose and look for early signs of effectiveness. This is…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Suzhou Suncadia Biopharmaceuticals Co., Ltd. • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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New drug aims to halt Cancer's deadly spread in first human test
Disease control Recruiting nowThis is the first-ever study in people of an experimental drug called metarrestin. The main goals are to find a safe dose and see if it can shrink tumors. It is for adults and teenagers (12+) with advanced solid tumors that have spread and have not been cured by standard treatmen…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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New Two-Target cancer drug enters first human trials
Disease control Recruiting nowThis is the first study in people to test a new experimental cancer drug called AK146D1. The main goals are to find a safe dose and see how the body processes the drug in up to 200 adults with advanced solid tumors that have progressed after standard treatments. Researchers will …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Akeso • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Cancer patients get chance to keep Life-Extending drugs
Disease control Recruiting nowThis study allows people with advanced solid tumors and a specific KRAS gene mutation to continue taking an experimental drug combination if they are already benefiting from it in a previous Amgen trial. The main goal is to check the long-term safety and side effects of continuin…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE2 • Sponsor: Amgen • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New cancer drug trial seeks to control advanced tumors
Disease control Recruiting nowThis study is testing a new medicine, SNV4818, for people with advanced solid tumors that have a specific genetic change (PIK3CA mutation). The main goals are to find the safest and most effective dose of SNV4818, both by itself and when combined with other cancer drugs. Research…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Pikavation Therapeutics, Inc. • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New 'Smart Bomb' drug trial offers hope for Tough-to-Treat cancers
Disease control Recruiting nowThis study is testing a new experimental cancer drug called LCB84. It is designed to target and deliver medicine directly to cancer cells in patients with advanced solid tumors that have stopped responding to standard treatments. The trial will first test the drug alone to find a…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: LigaChem Biosciences, Inc. • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New hope drug enters first human testing for tough cancers
Disease control Recruiting nowThis early-stage study is testing a new drug called SBO-154 in people with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find a safe dose and see how well the body tolerates the drug. Researchers will also check for early signs t…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Sun Pharma Advanced Research Company Limited • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New cancer injection enters first human tests
Disease control Recruiting nowThis is a first-in-human study to test the safety and find the right dose of a new drug called SIBP-A19 for people with advanced solid tumors. It will enroll about 156 adults whose cancer has progressed despite standard treatments. The main goal is to see how much of the drug the…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Shanghai Institute Of Biological Products • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New cancer drug enters first human safety trial
Disease control Recruiting nowThis is the first study in people to test a new drug called BAT8008 for advanced solid tumors. The main goal is to find a safe dose and understand how the drug moves through the body in patients whose cancer has progressed after standard treatments. Researchers will also look for…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Bio-Thera Solutions • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Canadian trial hunts for genetic keys to unlock cancer treatments
Disease control Recruiting nowThis study aims to see if matching existing cancer drugs to the specific genetic changes found in a person's tumor can help control advanced cancers. It is for adults with certain advanced solid tumors, lymphoma, or multiple myeloma who have run out of standard treatment options.…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE2 • Sponsor: Canadian Cancer Trials Group • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New weapon tested in fight against Tough-to-Treat cancers
Disease control Recruiting nowThis study is testing a new drug called DT-7012 for people with advanced solid tumors that have spread or returned after other treatments. The main goals are to find a safe dose and see if the drug, given alone or with an immunotherapy, can help control the cancer. It is an early…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Domain Therapeutics Australia Pty Ltd • Aim: Disease control
Last updated Mar 25, 2026 14:09 UTC
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New hope pill tested for Tough-to-Treat cancers
Disease control Recruiting nowThis is a first-in-human study testing a new oral drug called HW071021 for people with advanced solid tumors that have stopped responding to standard treatments. The trial aims to find a safe dose and see how the body processes the drug, while also checking for early signs that i…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Wuhan Humanwell Innovative Drug Research and Development Center Limited Company • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New hope for cancers that resist standard treatments
Disease control Recruiting nowThis study is testing whether combining two drugs can help people with aggressive cancers that have stopped responding to standard treatments. It focuses on small cell lung cancer and other cancers with specific genetic weaknesses that have become resistant to previous drugs. The…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Early trial tests simpler shot for advanced cancer treatment
Disease control Recruiting nowThis early-stage study is testing a new way to give the cancer drug rilvegostomig—as a simple injection under the skin instead of through an IV. It aims to find the right injection dose that gives similar drug levels in the body as the IV method and to check its safety. The study…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New pill tested for Tough-to-Treat cancers
Disease control Recruiting nowThis early-stage study is testing a new oral tablet called WJ22096 in patients with advanced solid tumors, like lung, colorectal, and pancreatic cancer, who have no other standard treatment options. The main goals are to find a safe dose, see how the body processes the drug, and …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Nanjing Jingao biomidical technology Co. Ltd. • Aim: Disease control
Last updated Mar 25, 2026 14:07 UTC
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First human trial launches for experimental Cancer-Fighting antibody
Disease control Recruiting nowThis early-stage study is testing a new experimental drug called JNJ-87890387 in people with advanced solid tumors that have spread or cannot be surgically removed. The main goals are to find a safe dose and understand how the body handles the drug. The trial is enrolling 200 adu…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated Mar 25, 2026 14:07 UTC
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First human tests begin for new cancer drug targeting rare genetic flaw
Disease control Recruiting nowThis early-stage study is testing a new oral drug called BMS-986504 in Japanese and Chinese patients with advanced solid tumors that have a specific genetic deletion called MTAP. The main goals are to check how safe the drug is, how well patients tolerate it, and how the drug mov…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated Mar 25, 2026 14:07 UTC
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New Triple-Action cancer drug enters human testing
Disease control Recruiting nowThis is an early-stage study testing a new experimental drug called CS2009 in people with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find a safe dose and see if the drug shows any early signs of fighting the cancer. The drug i…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: CStone Pharmaceuticals • Aim: Disease control
Last updated Mar 24, 2026 12:03 UTC
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New cancer drug trial seeks to control advanced tumors
Disease control Recruiting nowThis study is testing a new drug called CM518D1 in people with advanced solid tumors that have spread. Researchers want to find the safest dose and see if the drug helps shrink tumors. The trial will enroll 434 adults to check for side effects and measure how well the treatment w…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Keymed Biosciences Co.Ltd • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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New hope for tough cancers: first patients test experimental drug
Disease control Recruiting nowThis is the first study in people to test a new drug called GenSci140 for advanced solid tumors, like ovarian cancer. The main goals are to find a safe dose, understand how the body processes the drug, and see if it shows any early signs of helping to control the cancer. The stud…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Changchun GeneScience Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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New cancer drug trial seeks to control advanced tumors
Disease control Recruiting nowThis study is testing a new drug called TUB-030 in adults with advanced solid cancers that have not responded to other treatments. The main goals are to find the safest dose and see if the drug helps control the cancer. It will focus on specific cancers like head and neck cancer …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Tubulis GmbH • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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New weapon tested in fight against advanced cancers
Disease control Recruiting nowThis is a first-in-human study to test the safety and find the right dose of a new investigational drug called DB-1311 for people with advanced solid tumors that have progressed after standard treatments. The trial will enroll adults with various cancers to see how their bodies h…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: DualityBio Inc. • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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New pill targets common cancer driver in major trial
Disease control Recruiting nowThis study is testing a new oral drug called JAB-23E73 for adults with advanced solid tumors that have a specific genetic change called a KRAS alteration. The main goals are to find a safe and effective dose and to see if the drug can shrink tumors. It is for people whose cancer …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Jacobio Pharmaceuticals Co., Ltd. • Aim: Disease control
Last updated Mar 24, 2026 12:01 UTC
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New cancer pill targets genetic weakness in advanced tumors
Disease control Recruiting nowThis is a first-in-human study to test a new oral drug called FORX-428 in adults with advanced solid tumors that have specific genetic mutations, like BRCA1/2. The main goals are to find a safe dose and see how the body processes the drug. The study will enroll about 40 people wh…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: FoRx Therapeutics AG • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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New cancer drug enters first human trials for Tough-to-Treat tumors
Disease control Recruiting nowThis is the first study in humans to test a new experimental drug called HDM2006. It aims to find a safe dose and see early signs of whether it can help control advanced solid tumors in patients who have already tried standard treatments without success. The study will enroll abo…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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New pill targets genetic drivers in tough-to-treat cancers
Disease control Recruiting nowThis is the first study in people testing an experimental pill called TYRA-430. It aims to find a safe dose and see if it can help control advanced liver cancer and other solid tumors that have specific genetic changes in the FGF/FGFR pathway. The study will enroll about 100 adul…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Tyra Biosciences, Inc • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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New cancer pill enters first human trials for Tough-to-Treat tumors
Disease control Recruiting nowThis is the first study in people testing a new oral medication called GEN-725 for advanced solid tumors that have progressed after standard treatments. The main goals are to find a safe dose, see how the drug moves through the body, and check for any early signs that it might he…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Henan Genuine Biotech Co., Ltd. • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC
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New hope drug tested for Tough-to-Treat cancers
Disease control Recruiting nowThis early-stage trial is testing a new drug called AMT-253 for people with advanced melanoma or other solid tumors that have spread and cannot be removed by surgery. The study aims to find a safe dose and see if the drug can shrink tumors in patients who have already tried stand…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Multitude Therapeutics Inc. • Aim: Disease control
Last updated Mar 23, 2026 15:16 UTC
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Scientists test 'Cancer-Killing Virus' in patients
Disease control Recruiting nowThis early-stage study is testing a new treatment called JNJ-87704916, which is a modified virus designed to infect and kill cancer cells. It will be injected directly into tumors of patients with advanced solid tumors who have run out of standard treatment options. The main goal…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Johnson & Johnson Enterprise Innovation Inc. • Aim: Disease control
Last updated Mar 23, 2026 15:16 UTC
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First patients to try new pill targeting Hard-to-Treat cancers
Disease control Recruiting nowThis is the first study in people to test a new oral medication called JMKX005425. It aims to find a safe dose and see if it helps control advanced solid tumors that have specific genetic markers (MSI-H or dMMR). The study will enroll about 102 patients to check for side effects …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Jemincare • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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New cancer pill targets Hard-to-Treat tumors in early trial
Disease control Recruiting nowThis early-stage trial is testing a new oral medication called ST-01156 in adults with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find a safe dose and see how the body processes the drug. Researchers will also look for early s…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: SEED Therapeutics, Inc. • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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New drug targets 'Undruggable' KRAS cancer mutations in major trial
Disease control Recruiting nowThis early-stage clinical trial is testing a new drug called WEF-001 in people with advanced cancers that have a specific KRAS gene mutation. The study aims to find a safe dose and see if the drug can shrink tumors in cancers like pancreatic, colorectal, and lung cancer that have…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Auricula Biosciences Inc. • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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Moderna tests mRNA cancer vaccine in major new trial
Disease control Recruiting nowThis early-stage trial is testing the safety and effectiveness of an experimental mRNA cancer vaccine called mRNA-4359. It will be given alone and combined with approved immunotherapy drugs to 361 adults with advanced solid tumors like melanoma and lung cancer. The main goals are…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: ModernaTX, Inc. • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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New Two-Pronged attack on cancer enters human testing
Disease control Recruiting nowThis early-stage study is testing a new drug called OTP-01 in adults with advanced solid tumors that have progressed after standard treatments. The main goals are to find the safest and most effective dose, understand how the body processes the drug, and see if it can shrink tumo…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Ottimo Pharma Limited • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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New cancer drug enters human testing for Tough-to-Treat tumors
Disease control Recruiting nowThis is the first study in people testing a new cancer drug called HRS-3802. It aims to find a safe dose and see how the body handles the drug in 100 adults with advanced solid tumors that have not responded to standard treatments. Researchers will monitor for side effects and ch…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Shandong Suncadia Medicine Co., Ltd. • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC
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New cancer drug begins early human testing
Disease control Recruiting nowThis is an early-stage study to test the safety and find the right dose of a new drug called ACR246 for people with advanced solid tumors. It will involve about 77 adults whose cancer has continued to grow despite standard treatments. The main goal is to see how well the drug is …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Hangzhou Adcoris Biopharmacy Co., Ltd • Aim: Disease control
Last updated Mar 18, 2026 14:41 UTC
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First patients receive experimental cancer drug in new trial
Disease control Recruiting nowThis is the first study in people to test a new cancer drug called YL211. It aims to find a safe dose and see how the body processes the drug in patients with advanced solid tumors that have not responded to standard treatments. The main goals are to check for side effects and se…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd. • Aim: Disease control
Last updated Mar 18, 2026 14:40 UTC
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First human trial launches for experimental cancer drug targeting tough tumors
Disease control Recruiting nowThis early-stage clinical trial is testing a new experimental drug called BMS-986490, both alone and combined with an existing cancer drug (bevacizumab), for people with advanced solid tumors that have stopped responding to standard treatments. The study aims to determine if the …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated Mar 17, 2026 13:09 UTC
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New pill targets common cancer driver in advanced tumors
Disease control Recruiting nowThis early-stage trial is testing a new oral medication called ALTA3263 in adults with advanced solid tumors that have specific KRAS mutations. The study aims to find a safe dose and see how the body processes the drug, while also checking for early signs that it might help contr…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Alterome Therapeutics, Inc. • Aim: Disease control
Last updated Mar 17, 2026 13:09 UTC
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New cancer weapon enters human testing for Tough-to-Treat tumors
Disease control Recruiting nowThis is the first study in people testing a new experimental cancer drug called PHN-012. It aims to find a safe dose and see if it can shrink tumors in patients with advanced colon, lung, or pancreatic cancer who have no other standard treatments left. The study will enroll about…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Pheon Therapeutics • Aim: Disease control
Last updated Mar 17, 2026 13:08 UTC
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New pill targets genetic driver in multiple advanced cancers
Disease control Recruiting nowThis study is testing an oral pill called BAY2927088 for people with advanced solid tumors that have a specific genetic change (HER2 mutation). The goal is to see if the pill can shrink tumors and control the cancer's growth. About 111 adults with cancers like colorectal, breast,…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE2 • Sponsor: Bayer • Aim: Disease control
Last updated Mar 16, 2026 15:25 UTC
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New drug combo trial offers hope for Tough-to-Treat cancers
Disease control Recruiting nowThis study is testing a new drug called FL115 when given together with an existing immunotherapy drug (Sintilimab) for people with advanced solid tumors. The main goals are to find a safe dose and see if the combination shows early signs of helping to control the cancer. About 13…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Suzhou Forlong Biotechnology Co., Ltd • Aim: Disease control
Last updated Mar 16, 2026 15:25 UTC
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Supercharged immune cells tested as new weapon against tough cancers
Disease control Recruiting nowThis early-phase study is testing the safety and initial effectiveness of a new type of cell therapy called Meta10-TIL for people with advanced solid tumors that have stopped responding to standard treatments. Doctors take a patient's own immune cells from their tumor, modify the…
Matched conditions: ADVANCED SOLID TUMORS
Phase: EARLY_PHASE1 • Sponsor: Anhui Provincial Hospital • Aim: Disease control
Last updated Mar 16, 2026 15:24 UTC
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First patients to test new cancer pill in groundbreaking safety trial
Disease control Recruiting nowThis is the first time a new oral drug called SIGX1094R is being tested in people. The main goal is to find a safe dose and understand its side effects in patients with advanced solid tumors that have stopped responding to standard treatments. Researchers will also check if takin…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Signet Therapeutics • Aim: Disease control
Last updated Mar 16, 2026 15:24 UTC
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New pill offers hope for Tough-to-Treat cancers
Disease control Recruiting nowThis study is testing an experimental daily pill called ABP1011T for people with advanced solid tumors, like certain lung, esophageal, and cervical cancers, who have already tried and stopped responding to standard treatments. The main goal is to see if the pill can shrink tumors…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE2 • Sponsor: Shanghai AB PharmaTech Ltd. • Aim: Disease control
Last updated Mar 13, 2026 15:05 UTC
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New cancer drug enters human testing for advanced solid tumors
Disease control Recruiting nowThis study is testing a new drug called ASKG915 in people with advanced solid tumors that haven't responded to standard treatments. Researchers want to find the safest and most effective dose, first by giving the drug alone and then by combining it with standard cancer treatments…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: AskGene Pharma, Inc. • Aim: Disease control
Last updated Mar 12, 2026 13:51 UTC
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First human test of new encapsulated cancer therapy begins
Disease control Recruiting nowThis is the first study in people to test a new cancer drug called FID-022. It aims to find a safe dose and see how the body processes the drug in up to 24 adults with advanced solid tumors that have no standard curative treatments. The drug is given through an IV and contains ch…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Fulgent Pharma LLC. • Aim: Disease control
Last updated Mar 12, 2026 13:50 UTC
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First human tests begin for promising targeted cancer therapy
Disease control Recruiting nowThis early-stage study is testing a new drug called MK-1084 (calderasib) in people with advanced solid tumors that have a specific genetic change called KRAS G12C. The main goals are to find safe doses and see how the body processes the drug, both when given alone and combined wi…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Mar 09, 2026 14:25 UTC
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New cancer drug combo trial seeks to control advanced tumors
Disease control Recruiting nowThis trial is testing whether combining a drug called sirolimus with several newer antibody-drug conjugates (ADCs) is safe and effective for people with advanced solid tumors that have spread or can't be removed by surgery. Researchers will enroll about 444 patients to find the b…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: CSPC ZhongQi Pharmaceutical Technology Co., Ltd. • Aim: Disease control
Last updated Mar 09, 2026 14:25 UTC
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First human trial launches for new Cancer-Fighting drug
Disease control Recruiting nowThis is the first human study of an experimental drug called VVD-130037 for people with advanced solid tumors that have stopped responding to standard treatments. The trial aims to find the safest dose and see how the drug affects the body, both alone and when combined with other…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Vividion Therapeutics, Inc. • Aim: Disease control
Last updated Mar 09, 2026 14:23 UTC
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New cancer drug enters human testing for Tough-to-Treat tumors
Disease control Recruiting nowThis is a first-in-human study to test the safety and early signs of effectiveness of a new cancer drug called ZW191. It is for adults with advanced solid tumors, such as ovarian, endometrial, and non-small cell lung cancers, that have spread or returned. The main goal is to find…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Zymeworks BC Inc. • Aim: Disease control
Last updated Mar 06, 2026 15:38 UTC
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New targeted cancer drug enters human trials for advanced tumors
Disease control Recruiting nowThis early-stage study is testing a new experimental drug called ETX-636 in people with advanced solid tumors that have a specific genetic change (PIK3CA mutation). The trial will first check if the drug is safe and find the right dose, both when given alone and when combined wit…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Ensem Therapeutics • Aim: Disease control
Last updated Mar 04, 2026 15:29 UTC
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Experimental Two-Pronged attack on tough cancers begins human testing
Disease control Recruiting nowThis early-stage study is testing a new, experimental immunotherapy drug called REGN10597, both by itself and combined with an existing drug (cemiplimab), in people with advanced solid tumors like melanoma and kidney cancer. The main goals are to find a safe dose and see if the t…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1, PHASE2 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Mar 02, 2026 15:25 UTC
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New cancer drug enters first human testing
Disease control Recruiting nowThis is the first human trial testing a new antibody called GEN1079 for people with advanced solid tumors that have spread or cannot be removed by surgery. The study aims to find safe doses and see if the treatment shows early signs of helping control cancer. About 121 participan…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Genmab • Aim: Disease control
Last updated Mar 02, 2026 15:25 UTC
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New cancer drug targets specific protein in tumors
Disease control Recruiting nowThis study is testing a new drug called SKB315 for people with advanced solid tumors that have a specific protein called Claudin18.2. The main goals are to find a safe dose and see if the drug can help shrink tumors. It will involve about 246 participants whose cancer has not res…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. • Aim: Disease control
Last updated Mar 02, 2026 15:24 UTC
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First patients to test experimental cancer drug FP008
Disease control Recruiting nowThis is the first time researchers are testing the experimental drug FP008 in people with advanced solid tumors. The study aims to find a safe dose and see how the body processes the drug. It will also check if the drug shows any early signs of helping control cancer in patients …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Zhuhai Fapon Biopharma Co., Ltd. • Aim: Disease control
Last updated Feb 23, 2026 14:57 UTC
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Simple stockings could shield cancer patients from Treatment's painful side effect
Symptom relief Recruiting nowThis study is testing if wearing a medical compression stocking on one foot during cancer treatment can prevent nerve damage, a common and painful side effect. The trial involves 58 patients with advanced cancers who are receiving a specific type of targeted drug therapy. Researc…
Matched conditions: ADVANCED SOLID TUMORS
Phase: NA • Sponsor: Sheng Zhang • Aim: Symptom relief
Last updated Mar 30, 2026 14:31 UTC
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Early trial tests cancer drug safety for patients with liver issues
Knowledge-focused Recruiting nowThis early-stage study aims to understand how the cancer drug pralatrexate is processed by the body in people with varying degrees of liver impairment. It will involve about 24 adults with advanced solid tumors or blood cancers. The main goal is to measure drug levels in the bloo…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Acrotech Biopharma Inc. • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Scientists test new cancer Pill's safety with common drugs
Knowledge-focused Recruiting nowThis early-stage study aims to understand how a new oral cancer drug, rezatapopt, interacts with four common medications (metformin, rosuvastatin, repaglinide, and midazolam). It will enroll about 14 adults with advanced solid tumors that have a specific genetic mutation called T…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: PMV Pharmaceuticals, Inc • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:41 UTC
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Massive cancer study tracks Real-World results of precision drugs
Knowledge-focused Recruiting nowThis study aims to learn from real-world experience by observing how well FDA-approved targeted cancer drugs work for patients with advanced solid tumors, lymphoma, or multiple myeloma. It enrolls over 4,000 patients whose tumors have specific genetic changes that suggest a drug …
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE2 • Sponsor: American Society of Clinical Oncology • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Scientists test drug mix for advanced cancer patients
Knowledge-focused Recruiting nowThis early-stage study aims to understand how a common antifungal drug (itraconazole) affects the way the body processes a new experimental cancer drug (HS-20093). It involves 18 adults with advanced solid tumors who have no other standard treatment options. The main goal is to m…
Matched conditions: ADVANCED SOLID TUMORS
Phase: PHASE1 • Sponsor: Hansoh BioMedical R&D Company • Aim: Knowledge-focused
Last updated Mar 09, 2026 14:25 UTC