Can your Cancer's genes pick the right drug? TAPUR study aims to find out

NCT ID NCT02693535

Recruiting now Disease control Sponsor: American Society of Clinical Oncology Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

The TAPUR study is testing a wide range of targeted cancer drugs in people with advanced solid tumors, lymphoma, or multiple myeloma whose tumors have specific genetic changes. The goal is to see if matching drugs to these genetic variants can shrink tumors or stop them from growing. This real-world study enrolls patients who have run out of standard options, and results are shared publicly as they become available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: targeted cancer drugs (e.g., palbociclib, sunitinib, olaparib, nivolumab, and others)
What this could lead to: If successful, this study could help doctors match the right targeted drug to the right patient based on their tumor's genetic profile, improving cancer care.
What could go wrong: This is a Phase 2 registry study, not a controlled trial, so results may be less definitive. Many targeted drugs may not work as hoped for certain genetic variants.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

B-cell non-Hodgkin lymphoma lymphoma, non-Hodgkin, familial neoplasm non-Hodgkin lymphoma plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVANCED SOLID TUMORS LYMPHOMA, NON-HODGKIN MULTIPLE MYELOMA

Contacts and locations

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Locations

Atrium Health's Levine Cancer Institute
RECRUITING

Charlotte, North Carolina, 28277, United States
Aurora Bay Area Medical Center
RECRUITING

Marinette, Wisconsin, 54143, United States
Aurora BayCare Medical Center
RECRUITING

Green Bay, Wisconsin, 54311, United States
Aurora Cancer Care - Burlington
RECRUITING

Burlington, Wisconsin, 53105, United States
Aurora Cancer Care - Grafton
RECRUITING

Grafton, Wisconsin, 53024, United States
Aurora Cancer Care - Kenosha South
RECRUITING

Kenosha, Wisconsin, 53142, United States
Aurora Cancer Care - Milwaukee West
RECRUITING

Wauwatosa, Wisconsin, 53226, United States
Aurora Cancer Care - Racine
RECRUITING

Racine, Wisconsin, 53406, United States
Aurora Cancer Care Milwaukee
RECRUITING

Milwaukee, Wisconsin, 53209, United States
Aurora Health Care - Germantown Health Center
RECRUITING

Germantown, Wisconsin, 53022, United States
Aurora Medical Center in Summit
RECRUITING

Summit, Wisconsin, 53066, United States
Aurora Sinai Medical Center
RECRUITING

Milwaukee, Wisconsin, 53223, United States
Aurora St. Luke's Medical Center
RECRUITING

Milwaukee, Wisconsin, 53215, United States
Aurora West Allis Medical Center
RECRUITING

Milwaukee, Wisconsin, 53227, United States
California Pacific Medical Center Research Institute
RECRUITING

San Francisco, California, 94115, United States

Contact Email: •••••@•••••
Cancer Research Consortium of West Michigan
RECRUITING

Grand Rapids, Michigan, 49503, United States
Cancer Treatment Centers of America - Atlanta
RECRUITING

Atlanta, Georgia, 30265, United States
Cancer Treatment Centers of America-Chicago
RECRUITING

Chicago, Illinois, 60099, United States

Contact Email: •••••@•••••
Cancer Treatment Centers of America-Phoenix
RECRUITING

Phoenix, Arizona, 85338, United States
Cedar City Hospital, SW Cancer Clinic, Sandra Maxwell Cancer Center
RECRUITING

Cedar City, Utah, 84720, United States
Charlotte Hungerford
RECRUITING

Torrington, Connecticut, 06790, United States

Contact Email: •••••@•••••
Cohen Children's Medical Center
RECRUITING

New Hyde Park, New York, 11040, United States
Community Health Network (The University of Texas MD Anderson Cancer Center)
RECRUITING

Indianapolis, Indiana, 46250, United States
Dixie Regional Medical Center-River Road Campus
RECRUITING

St. George, Utah, 84770, United States
Emory University Winship Cancer Institute
RECRUITING

Atlanta, Georgia, 30322, United States
Florida Cancer Specialists North / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Altamonte Springs, Florida, 32701, United States
Florida Cancer Specialists North / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Brandon, Florida, 33511, United States
Florida Cancer Specialists North / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Clearwater, Florida, 33761, United States
Florida Cancer Specialists North / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Gainesville, Florida, 32605, United States
Florida Cancer Specialists North / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Largo, Florida, 33770, United States
Florida Cancer Specialists North / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Lecanto, Florida, 34461, United States
Florida Cancer Specialists North / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Ocala, Florida, 34474, United States
Florida Cancer Specialists North / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Orange City, Florida, 32763, United States
Florida Cancer Specialists North / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Orlando, Florida, 32806, United States
Florida Cancer Specialists North / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

St. Petersburg, Florida, 33701, United States
Florida Cancer Specialists North / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Tampa, Florida, 33607, United States
Florida Cancer Specialists North / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Tavares, Florida, 32778, United States
Florida Cancer Specialists North / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

The Villages, Florida, 32159, United States
Florida Cancer Specialists North / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Trinity, Florida, 34655, United States
Florida Cancer Specialists North / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Winter Park, Florida, 32789, United States
Florida Cancer Specialists South / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Bonita Springs, Florida, 34135, United States
Florida Cancer Specialists South / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Bradenton, Florida, 34211, United States
Florida Cancer Specialists South / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Cape Coral, Florida, 33909, United States
Florida Cancer Specialists South / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Fort Myers, Florida, 33901, United States
Florida Cancer Specialists South / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Fort Myers, Florida, 33905, United States
Florida Cancer Specialists South / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Fort Myers, Florida, 33908, United States
Florida Cancer Specialists South / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Naples, Florida, 34102, United States
Florida Cancer Specialists South / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Port Charlotte, Florida, 33980, United States
Florida Cancer Specialists South / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Sarasota, Florida, 34232, United States
Florida Cancer Specialists South / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Sarasota, Florida, 34236, United States
Florida Cancer Specialists South / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Venice, Florida, 34285, United States
Florida Cancer Specialists South / Sarah Cannon Research Institute
ACTIVE_NOT_RECRUITING

Venice, Florida, 34292, United States
Fox Chase Cancer Center
RECRUITING

Philadelphia, Pennsylvania, 19111, United States
Genesys Hurley Cancer Institute
RECRUITING

Flint, Michigan, 48503, United States

Contact Email: •••••@•••••
Gynecologic Oncology and Surgical Specialists at the Lewis Cancer & Research Pavilion
RECRUITING

Savannah, Georgia, 31405, United States
Harold Alfond Center for Cancer Care
RECRUITING

Augusta, Maine, 04330, United States
Hartford Hospital
RECRUITING

Hartford, Connecticut, 06102, United States

Contact Email: •••••@•••••
Henry Ford Health Saint John Hospital
RECRUITING

Detroit, Michigan, 48236, United States

Contact Email: •••••@•••••
Henry Ford Health Warren Hospital
RECRUITING

Warren, Michigan, 48093, United States

Contact Email: •••••@•••••
Holy Cross Hospital
RECRUITING

Fort Lauderdale, Florida, 33308, United States

Contact Email: •••••@•••••
Inova Schar Cancer Institute
RECRUITING

Fairfax, Virginia, 22042, United States
Intermountain Healthcare
RECRUITING

Salt Lake City, Utah, 84107, United States
Jackson Laboratory - Maine Cancer Genomics Initiative
RECRUITING

Augusta, Maine, 04330, United States
Kaiser Permanente - Oakland Medical Center
RECRUITING

Oakland, California, 94611, United States
Kaiser Permanente - Roseville Medical Center
RECRUITING

Roseville, California, 95661, United States
Kaiser Permanente - Sacramento Medical Center
RECRUITING

Sacramento, California, 95814, United States
Kaiser Permanente - San Francisco Medical Center
RECRUITING

San Francisco, California, 94115, United States
Kaiser Permanente - San Jose Medical Center
RECRUITING

San Jose, California, 95119, United States
Kaiser Permanente - San Leandro Medical Center
RECRUITING

San Leandro, California, 94577, United States
Kaiser Permanente - Santa Clara Medical Center
RECRUITING

Santa Clara, California, 95051, United States
Kaiser Permanente - South San Francisco Medical Center
RECRUITING

San Francisco, California, 94080, United States
Kaiser Permanente - Vallejo Medical Center
RECRUITING

Vallejo, California, 94589, United States
Kaiser Permanente - Walnut Creek Medical Center
RECRUITING

Walnut Creek, California, 94596, United States
Kettering Health
RECRUITING

Kettering, Ohio, 45429, United States
Lehigh Valley Hospital - Cedar Crest
RECRUITING

Allentown, Pennsylvania, 18103, United States

Contact Email: •••••@•••••
Lehigh Valley Hospital- Muhlenberg
RECRUITING

Bethlehem, Pennsylvania, 18017, United States

Contact Email: •••••@•••••
Lehigh Valley Hospital-Hazleton
RECRUITING

Hazleton, Pennsylvania, 18201, United States

Contact Email: •••••@•••••
Lewis Cancer & Research Pavilion
RECRUITING

Savannah, Georgia, 31405, United States
Lewis Cancer & Research Pavilion at the Melanoma, Skin Cancer & Sarcoma Institute
RECRUITING

Savannah, Georgia, 31405, United States
Lineberger Comprehensive Cancer Center
RECRUITING

Chapel Hill, North Carolina, 27599, United States
Lovelace Medical Center - Saint Joseph Square
RECRUITING

Albuquerque, New Mexico, 87102, United States
Maine Children's Cancer Program
RECRUITING

Scarborough, Maine, 04074, United States
Maine Medical Partner's Women's Health
RECRUITING

Scarborough, Maine, 04074, United States
MaineHealth Cancer Care -Brunswick
RECRUITING

Brunswick, Maine, 04011, United States
MaineHealth Cancer Care -South Portland
RECRUITING

South Portland, Maine, 04106, United States
Manhattan Eye, Ear, and Throat Hospital
RECRUITING

New York, New York, 10065, United States
Memorial Medical Center
RECRUITING

Las Cruces, New Mexico, 88011, United States
Michigan Cancer Research Consortium
RECRUITING

Traverse City, Michigan, 48341, United States
Midstate Medical Center (MSMC)
RECRUITING

Meriden, Connecticut, 06451, United States

Contact Email: •••••@•••••
MyMichigan Medical Center Saginaw
RECRUITING

Saginaw, Michigan, 48601, United States

Contact Email: •••••@•••••
NH Oncology - Hematology, PA
RECRUITING

Concord, New Hampshire, 03103, United States
New England Cancer Specialist
RECRUITING

Kennebunk, Maine, 04043, United States
New England Cancer Specialist
RECRUITING

Scarborough, Maine, 04074, United States
New England Cancer Specialist
RECRUITING

Topsham, Maine, 04086, United States
New England Cancer Specialist
RECRUITING

Portsmouth, New Hampshire, 03801, United States
Northern Light Cancer Care
RECRUITING

Brewer, Maine, 04412, United States
Northern Westchester Hospital
RECRUITING

Mount Kisco, New York, 10549, United States
Northwell Health Monter Cancer Center
RECRUITING

Lake Success, New York, 11042, United States
Northwest Medical Specialties
RECRUITING

Bonney Lake, Washington, 98391, United States

Contact Email: •••••@•••••
Northwest Medical Specialties
RECRUITING

Federal Way, Washington, 98003, United States

Contact Email: •••••@•••••
Northwest Medical Specialties
RECRUITING

Gig Harbor, Washington, 98332, United States

Contact Email: •••••@•••••
Northwest Medical Specialties
RECRUITING

Olympia, Washington, 98502, United States

Contact Email: •••••@•••••
Northwest Medical Specialties
RECRUITING

Puyallup, Washington, 98373, United States
Northwest Medical Specialties
RECRUITING

Tacoma, Washington, 98405, United States
PanOncology Trials
RECRUITING

Cayey, 00737, Puerto Rico
PanOncology Trials
RECRUITING

Dorado, 00646, Puerto Rico
PanOncology Trials
RECRUITING

Manati, 00674, Puerto Rico
PanOncology Trials
RECRUITING

Mayagüez, 00680, Puerto Rico
PanOncology Trials
RECRUITING

Ponce, 00730, Puerto Rico
PanOncology Trials
RECRUITING

San Juan, 00909, Puerto Rico
PanOncology Trials
RECRUITING

San Juan, 00935, Puerto Rico
Penobscot Bay Medical Center
RECRUITING

Rockport, Maine, 04856, United States
Phelps Hospital
RECRUITING

Sleepy Hollow, New York, 10591, United States
Pocono Medical Center
RECRUITING

East Stroudsburg, Pennsylvania, 18301, United States

Contact Email: •••••@•••••
Presbyterian Kaseman Hospital
RECRUITING

Albuquerque, New Mexico, 87110, United States
Presbyterian Rust Medical Center
RECRUITING

Rio Rancho, New Mexico, 87124, United States
Providence Health & Services
RECRUITING

Portland, Oregon, 97213, United States
Queens Cancer Center
RECRUITING

Rego Park, New York, 11374, United States
Raish Peavey Haskell Children's Cancer and Treatment Center
RECRUITING

Brewer, Maine, 04412, United States
SC Cancer Specialists at St. Joseph's/Candler Bluffton
RECRUITING

Bluffton, South Carolina, 29910, United States
SMHC Cancer Care and Blood Disorders -Biddeford
RECRUITING

Biddeford, Maine, 04005, United States
SMHC Cancer Care and Blood Disorders -Sandford
RECRUITING

Sanford, Maine, 04073, United States
Saint Vincent's Medical Center (SVMC)
RECRUITING

Bridgeport, Connecticut, 06606, United States

Contact Email: •••••@•••••
Sanford Cancer Center Oncology Clinic and Pharmacy
RECRUITING

Sioux Falls, South Dakota, 57104, United States
Sanford Health- Bismarck
RECRUITING

Bismarck, North Dakota, 58501, United States
Sanford Health- Fargo
RECRUITING

Fargo, North Dakota, 58122, United States
Solinsky Center for Cancer Care
RECRUITING

Manchester, New Hampshire, 03103, United States
South Carolina Cancer Specialists
RECRUITING

Hilton Head Island, South Carolina, 29926, United States
St. Joseph's/Candler Smith
RECRUITING

Bluffton, South Carolina, 29910, United States
Staten Island University Hospital
RECRUITING

New York, New York, 10305, United States
Stephens Memorial Hospital
RECRUITING

Norway, Maine, 04268, United States
Summit Cancer Care
RECRUITING

Savannah, Georgia, 31405, United States
Summit Cancer Care at St. Josph's/Candler Bluffton
RECRUITING

Bluffton, South Carolina, 29910, United States
Sutter Alta Bates
RECRUITING

Berkeley, California, 94705, United States
Sutter Auburn
RECRUITING

Auburn, California, 95602, United States
Sutter Cancer Research Consortium
RECRUITING

San Francisco, California, 94115, United States
Sutter Palo Alto Medical Foundation: Fremont
RECRUITING

Santa Cruz, California, 994538, United States

Contact Email: •••••@•••••
Sutter Palo Alto Medical Foundation: Palo Alto
RECRUITING

Palo Alto, California, 94301, United States

Contact Email: •••••@•••••
Sutter Palo Alto Medical Foundation: Santa Cruz
RECRUITING

Santa Cruz, California, 95065, United States

Contact Email: •••••@•••••
Sutter Palo Alto Medical Foundation: Sunnyvale
RECRUITING

Sunnyvale, California, 94086, United States

Contact Email: •••••@•••••
Sutter Roseville
RECRUITING

Roseville, California, 95661, United States
Sutter Sacramento
RECRUITING

Sacramento, California, 95816, United States
Sutter Sansum Clinic
RECRUITING

Santa Barbara, California, 93105, United States
Swedish Cancer Institute
RECRUITING

Seattle, Washington, 98104, United States
Tennessee Oncology - Nashville / Sarah Cannon Research Institute
RECRUITING

Nashville, Tennessee, 37203, United States
The Angeles Clinic and Research Institute, A Cedars-Sinai Affiliate
RECRUITING

Los Angeles, California, 90025, United States
The Hospital of Central Connecticut (HOCC) Cancer Center
RECRUITING

New Britain, Connecticut, 06053, United States

Contact Email: •••••@•••••
The Queen's Medical Center - Kuakini
RECRUITING

Honolulu, Hawaii, 96817, United States
The Queen's Medical Center - POB I
RECRUITING

Honolulu, Hawaii, 96813, United States
The Queen's Medical Center - Punchbowl
RECRUITING

Honolulu, Hawaii, 96813, United States
The Queen's Medical Center - West Oahu
RECRUITING

‘Ewa Beach, Hawaii, 96706, United States
The University of New Mexico Comprehensive Cancer Center
RECRUITING

Albuquerque, New Mexico, 87131, United States
The University of Texas MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
Trinity Health Ann Arbor Hospital
RECRUITING

Ann Arbor, Michigan, 48106, United States

Contact Email: •••••@•••••
Trinity Health Livonia Hospital
RECRUITING

Livonia, Michigan, 48154, United States

Contact Email: •••••@•••••
Trinity Health Oakland Hospital
RECRUITING

Pontiac, Michigan, 48341, United States

Contact Email: •••••@•••••
University of Alabama at Birmingham Comprehensive Cancer Center
RECRUITING

Birmingham, Alabama, 35294, United States
University of Cincinnati Medical Center
RECRUITING

Cincinnati, Ohio, 45219, United States
University of Florida Health
RECRUITING

Gainesville, Florida, 32610, United States
University of Miami Sylvester Comprehensive Cancer Center
RECRUITING

Miami, Florida, 33136, United States
University of Miami/Sylvester Cancer Institute - Alex's Place
RECRUITING

Miami, Florida, 33136, United States
University of Miami/Sylvester Cancer Institute - Aventura
RECRUITING

Aventura, Florida, 33180, United States
University of Miami/Sylvester Cancer Institute - Deerfield Beach
RECRUITING

Deerfield Beach, Florida, 33442, United States
University of Miami/Sylvester Cancer Institute - Griffin Cancer Research Building
RECRUITING

Miami, Florida, 33136, United States
University of Miami/Sylvester Cancer Institute - Kendall
RECRUITING

Miami, Florida, 33176, United States
University of Miami/Sylvester Cancer Institute - Lennar
RECRUITING

Coral Gables, Florida, 33146, United States
University of Miami/Sylvester Cancer Institute - Plantation
RECRUITING

Plantation, Florida, 33324, United States
University of Miami/Sylvester Cancer Institute - Sole Mia
RECRUITING

Miami, Florida, 33181, United States
University of Michigan
ACTIVE_NOT_RECRUITING

Ann Arbor, Michigan, 48109, United States
University of Michigan Health - Sparrow Lansing
RECRUITING

Lansing, Michigan, 48912, United States

Contact Email: •••••@•••••
University of Nebraska Medical Center
RECRUITING

Omaha, Nebraska, 68198, United States
Vince Lombardi Cancer Center
RECRUITING

Sheboygan, Wisconsin, 53081, United States
Vince Lombardi Cancer Clinic - Oshkosh
RECRUITING

Oshkosh, Wisconsin, 54904, United States
Vince Lombardi Cancer Clinic - Two Rivers
RECRUITING

Two Rivers, Wisconsin, 54241, United States
Waldo County General Hospital
RECRUITING

Belfast, Maine, 04915, United States
West Chester Hospital
RECRUITING

West Chester, Ohio, 45069, United States
William W. Backus Hospital
RECRUITING

Norwich, Connecticut, 06360, United States

Contact Email: •••••@•••••
Windham Hospital (WH)
RECRUITING

Willimantic, Connecticut, 06226, United States

Contact Email: •••••@•••••
York Hopsital Oncology & Infusion Care in Kittery
RECRUITING

Kittery, Maine, 03904, United States
York Hospital Oncology & Infusion Care in Wells
RECRUITING

Wells, Maine, 04090, United States
York Hospital Oncology & Infusion Care in York
RECRUITING

York Village, Maine, 03909, United States

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