New drug BG-C477 enters human testing for Hard-to-Treat cancers

NCT ID NCT06596473

Recruiting now Disease control Sponsor: BeOne Medicines Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 09, 2026 · Updated 2 times

Summary

This early-phase study tests a new drug, BG-C477, in about 310 people with advanced solid tumors that have not responded to standard treatments. The main goals are to check the drug's safety, find the best dose, and see if it can shrink tumors. The study is open-label, meaning everyone knows they are getting the drug.

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Conditions

The condition(s) this trial relates to.

neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVANCED SOLID TUMORS

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Auckland City Hospital
RECRUITING

Auckland, 1023, New Zealand
Beijing Chest Hospital, Capital Medical University
RECRUITING

Beijing, Beijing Municipality, 101149, China
Blacktown Cancer and Haematology Centre
RECRUITING

Blacktown, New South Wales, NSW 2148, Australia
Cancer Hospital Chinese Academy of Medical Sciences
RECRUITING

Beijing, Beijing Municipality, 100021, China
Cancer Institute Hospital of Jfcr
RECRUITING

Kotoku, Tokyo, 135-8550, Japan
Cancer Research South Australia
RECRUITING

Adelaide, South Australia, SA 5000, Australia
Chongqing University Cancer Hospital
RECRUITING

Chongqing, Chongqing Municipality, 400030, China
City of Hope National Medical Center
RECRUITING

Duarte, California, 91010-3012, United States
City of Hope Phoenix Cancer Center
RECRUITING

Goodyear, Arizona, 85338, United States
Fujian Cancer Hospital
RECRUITING

Fuzhou, Fujian, 350014, China
Guangxi Medical University Cancer Hospital Wuxiang Branch
RECRUITING

Nanning, Guangxi, 530201, China
Harbin Medical University Cancer Hospital
RECRUITING

Harbin, Heilongjiang, 150000, China
Henan Cancer Hospital
RECRUITING

Zhengzhou, Henan, 450000, China
Hospital Kuala Lumpur
RECRUITING

Kuala Lumpur, 50586, Malaysia
Hospital Wanita Dan Kanak Kanak Sabah (Hospital Likas)
RECRUITING

Kota Kinabalu Sabah, 88996, Malaysia
Hubei Cancer Hospital
RECRUITING

Wuhan, Hubei, 430079, China
Jiamusi Cancer Hospital
RECRUITING

Jiamusi, Heilongjiang, 154004, China
Jiangsu Province Hospital
RECRUITING

Nanjing, Jiangsu, 210029, China
Jiangxi Cancer Hospital
RECRUITING

Nanchang, Jiangxi, 330029, China
Jining No1 Peoples Hospital East Branch
RECRUITING

Jining, Shandong, 272002, China
John Theurer Cancer Center Hackensack University Medical Center
RECRUITING

Hackensack, New Jersey, 07601, United States
Kansai Medical University Hospital
RECRUITING

Hirakata, Osaka, 573-1191, Japan
King Chulalongkorn Memorial Hospital (Chulalongkorn University)
RECRUITING

Pathum Wan, 10330, Thailand
Linyi Peoples Hospital Beicheng Branch
RECRUITING

Linyi, Shandong, 276005, China
Nanfang Hospital, Southern Medical University
RECRUITING

Guangzhou, Guangdong, 510515, China
National Cancer Institute (Institut Kanser Negara)
RECRUITING

Putrajaya, 62250, Malaysia
Northern Beaches Hospital
RECRUITING

Frenchs Forest, New South Wales, NSW 2086, Australia
One Clinical Research
RECRUITING

Nedlands, Western Australia, WA 6009, Australia
Osf Saint Francis Medical Center
RECRUITING

Peoria, Illinois, 61637, United States
Sarawak General Hospital
RECRUITING

Kuching, 93586, Malaysia
Shanghai Pulmonary Hospital
RECRUITING

Shanghai, Shanghai Municipality, 200433, China
Shizuoka Cancer Center
RECRUITING

Suntogun, Shizuoka, 411-8777, Japan
Siriraj Hospital
RECRUITING

Bangkok, 10700, Thailand
Srinagarind Hospital (Khon Kaen University)
RECRUITING

Muang, 40002, Thailand
Sun Yat Sen University Cancer Center
RECRUITING

Guangzhou, Guangdong, 510060, China
Sunshine Coast University Private Hospital
RECRUITING

Birtinya, Queensland, QLD 4575, Australia
Sunway Medical Centre
RECRUITING

Petaling Jaya, 47500, Malaysia
Taizhou Hospital of Zhejiang Province (East)
RECRUITING

Taizhou, Zhejiang, 317004, China
Texas Oncology Longview
RECRUITING

Longview, Texas, 75601, United States
The Alfred Hospital
RECRUITING

Melbourne, Victoria, VIC 3004, Australia
The First Affiliated Hospital of Nanchang University Branch Xianghu
RECRUITING

Nanchang, Jiangxi, 332000, China
The First Affiliated Hospital of Soochow University
RECRUITING

Suzhou, Jiangsu, 215006, China
The First Affiliated Hospital of Wenzhou Medical University
RECRUITING

Wenzhou, Zhejiang, 325000, China
The First Affiliated Hospital of Zhengzhou University
ACTIVE_NOT_RECRUITING

Zhengzhou, Henan, 450052, China
The First Affiliated Hospital, Zhejiang University School of Medicinechengzhan
RECRUITING

Hangzhou, Zhejiang, 310002, China
The First Hospital of China Medical University
RECRUITING

Shenyang, Liaoning, 110001, China
The University of Kansas Cancer Center
RECRUITING

Westwood, Kansas, 66205-2003, United States
The University of Texas Md Anderson Cancer Center
RECRUITING

Houston, Texas, 77030-4009, United States
Tianjin Medical University Cancer Institute and Hospital
RECRUITING

Tianjin, Tianjin Municipality, 300060, China
Tokyo Metropolitan Komagome Hospital
RECRUITING

Bunkyoku, Tokyo, 113-8677, Japan
University of Colorado Cancer Center
RECRUITING

Aurora, Colorado, 80045-2517, United States
West China Hospital, Sichuan University
RECRUITING

Chengdu, Sichuan, 610041, China
Yale University Yale Cancer Center
RECRUITING

New Haven, Connecticut, 06520-8028, United States
Yunnan Cancer Hospital
RECRUITING

Kunming, Yunnan, 650100, China

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