New drug combo shows promise for Hard-to-Treat cancers

NCT ID NCT07169994

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a new drug called YL202 combined with other anti-cancer medicines (toripalimab or furmonertinib) in people with advanced solid tumors, including breast and lung cancer. The goal is to find safe doses and see if the combination shrinks tumors. About 414 adults aged 18-75 who have tried standard treatments are being recruited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

YL202 (a drug) combined with toripalimab or furmonertinib mesilate

What this could lead to

If successful, this could point toward a new treatment option for people with advanced solid tumors that have not responded to standard therapies.

What could go wrong

This is an early-phase trial (phase Ib/II) with a small number of participants, so the safety and effectiveness are not yet proven. There is a risk of side effects, and the combination may not work for all tumor types.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affiliated Hospital Of Hebei University

    NOT_YET_RECRUITING

    Baoding, Hebei, 71051, China

    Contact

  • Affiliated Zhongshan Hospital Dalian University

    NOT_YET_RECRUITING

    Dalian, Liaoning, 116001, China

    Contact

  • Affiliated Zhongshan Hospital Dalian University

    NOT_YET_RECRUITING

    Jinan, Shandong, 250117, China

    Contact

  • Anhui Provincial Hospital(The First Affiliated Hospital of Ustc)

    NOT_YET_RECRUITING

    Hefei, Anhui, 230001, China

    Contact

  • Anyang Cancer Hospital

    NOT_YET_RECRUITING

    Anyang, Henan, 455100, China

    Contact

  • Fudan University Shanghai Cancer Center

    RECRUITING

    Shanghai, Shanghai Municipality, 201321, China

    Contact

  • Fujian Cancer Hospital

    NOT_YET_RECRUITING

    Fuzhou, Fujian, 350014, China

    Contact

  • Ghang xi Medical University Cancer Hospital

    NOT_YET_RECRUITING

    Nanning, Guangxi, 530028, China

    Contact

  • Harbin Medical University Cancer Hospital

    NOT_YET_RECRUITING

    Harbin, Heilongjiang, 150081, China

    Contact

  • Jiangsu Province Hospital(The First Affiliated Hospital With Nanjing Medical University, Jiangsu Women And Children Health Hospital)

    NOT_YET_RECRUITING

    Nanjing, Jiangsu, 210029, China

    Contact

  • Jiangxi Cancer Hospital

    NOT_YET_RECRUITING

    Nanchang, Jiangxi, China

    Contact

  • Liaoning cancer hospital &institute

    NOT_YET_RECRUITING

    Shenyang, Liaoning, 110042, China

    Contact

  • Meizhou People's Hospital(Huangtang Hospital)Meizhou Academy of Medical Sciences

    NOT_YET_RECRUITING

    Meizhou, Guangdong, 514031, China

    Contact

  • Shanxi Cancer Hospital

    NOT_YET_RECRUITING

    Taiyuan, Shanxi, 30013, China

    Contact

  • Sichuan Academy of Medical Sciences&Sichuan Provincial People's Hospital

    NOT_YET_RECRUITING

    Sichuan, Sichuan, 610072, China

    Contact

  • Sun Yat-sen University Cancer Center

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, 510555, China

    Contact

  • The First Affiliated Hospital of Henan University of Science and Technology

    NOT_YET_RECRUITING

    Luoyang, Henan, 471023, China

    Contact

  • The First People's Hospital of Changde City

    NOT_YET_RECRUITING

    Changde, Hunan, 415000, China

    Contact

  • Tianjin Cancer Hospital Airport Hospital

    NOT_YET_RECRUITING

    Tianjin, Tianjin Municipality, 300300, China

    Contact

  • Xiangyang Central Hospital

    NOT_YET_RECRUITING

    Xiangyang, Hubei, 441138, China

    Contact