New cancer drug SBO-154 enters human testing for advanced tumors
NCT ID NCT07042100
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial tests a new biologic drug called SBO-154 in 177 people with advanced solid tumors that have not responded to or cannot tolerate standard treatments. The main goals are to check safety, find the right dose, and get a first look at whether the drug can shrink tumors. Participants receive the drug by IV every three weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- SBO-154 (a biologic drug given intravenously every 3 weeks)
- What this could lead to
- If it works, this could point toward a new treatment option for people with advanced solid tumors who have not responded to standard therapies.
- What could go wrong
- This is a very early Phase 1 trial focused on safety, not proof of effectiveness. The drug may not shrink tumors or could cause side effects. Success is uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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All India Institute for Medical Sciences
RECRUITINGDelhi, New Delhi, 110029, India
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Amrita Institute of Medical Sciences
NOT_YET_RECRUITINGErnākulam, Kerala, 682041, India
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cancer Research South Australia
RECRUITINGAdelaide, South Australia, 5000, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Honorhealth Research Institute
RECRUITINGScottsdale, Arizona, 85258, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hope and Healing Clinical Research LLC
RECRUITINGHinsdale, Illinois, 60521, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Kainos Super Speciality Hopsital
NOT_YET_RECRUITINGRohtak, Haryana, 124001, India
Contact Phone: •••-•••-•••• Email: •••••@•••••
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Noble Hospital Pvt. Ltd.
RECRUITINGPune, Maharashtra, 411013, India
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Pacific Medical College and Hospital
NOT_YET_RECRUITINGUdaipur, Rajasthan, 313001, India
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sarcoma Oncology Research Center
RECRUITINGSanta Monica, California, 90403, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Scientia Clinical Research
RECRUITINGRandwick, New South Wales, 2031, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sir H.N Reliance Foundation Hospital
NOT_YET_RECRUITINGMumbai, Maharashtra, 400004, India
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sunshine Coast University Private Hospital
RECRUITINGBirtinya, Queensland, 4557, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Tata Memorial hospital
RECRUITINGMumbai, Maharashtra, 400012, India
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Yale University - Yale Cancer Center
RECRUITINGNew Haven, Connecticut, 06510, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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