New cancer drug SBO-154 enters human testing for advanced tumors

NCT ID NCT07042100

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tests a new biologic drug called SBO-154 in 177 people with advanced solid tumors that have not responded to or cannot tolerate standard treatments. The main goals are to check safety, find the right dose, and get a first look at whether the drug can shrink tumors. Participants receive the drug by IV every three weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
SBO-154 (a biologic drug given intravenously every 3 weeks)
What this could lead to
If it works, this could point toward a new treatment option for people with advanced solid tumors who have not responded to standard therapies.
What could go wrong
This is a very early Phase 1 trial focused on safety, not proof of effectiveness. The drug may not shrink tumors or could cause side effects. Success is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • All India Institute for Medical Sciences

    RECRUITING

    Delhi, New Delhi, 110029, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Amrita Institute of Medical Sciences

    NOT_YET_RECRUITING

    Ernākulam, Kerala, 682041, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cancer Research South Australia

    RECRUITING

    Adelaide, South Australia, 5000, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Honorhealth Research Institute

    RECRUITING

    Scottsdale, Arizona, 85258, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hope and Healing Clinical Research LLC

    RECRUITING

    Hinsdale, Illinois, 60521, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kainos Super Speciality Hopsital

    NOT_YET_RECRUITING

    Rohtak, Haryana, 124001, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Noble Hospital Pvt. Ltd.

    RECRUITING

    Pune, Maharashtra, 411013, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Pacific Medical College and Hospital

    NOT_YET_RECRUITING

    Udaipur, Rajasthan, 313001, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sarcoma Oncology Research Center

    RECRUITING

    Santa Monica, California, 90403, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Scientia Clinical Research

    RECRUITING

    Randwick, New South Wales, 2031, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sir H.N Reliance Foundation Hospital

    NOT_YET_RECRUITING

    Mumbai, Maharashtra, 400004, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sunshine Coast University Private Hospital

    RECRUITING

    Birtinya, Queensland, 4557, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tata Memorial hospital

    RECRUITING

    Mumbai, Maharashtra, 400012, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Yale University - Yale Cancer Center

    RECRUITING

    New Haven, Connecticut, 06510, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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