New drug INCA33890 enters human trials for Hard-to-Treat cancers
NCT ID NCT05836324
First seen Nov 20, 2025 · Last updated May 13, 2026 · Updated 22 times
Summary
This early-phase study tests a new drug called INCA33890 in about 408 adults with advanced or metastatic solid tumors that have not responded to standard treatments. The main goals are to check the drug's safety, find the best dose, and see if it can shrink tumors. Participants must be 18 or older and have tried or cannot take available therapies.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cambridge University Hospitals Nhs Foundation Trust
RECRUITINGCambridge, CB2 0QQ, United Kingdom
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Cancer and Hematology Centers of Western Michigan-Start Midwest
RECRUITINGGrand Rapids, Michigan, 49546, United States
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Centre Hospitalier Universitaire Vaudois (Chuv)
RECRUITINGLausanne, 01011, Switzerland
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Centre Leon Berard
RECRUITINGLyon, 69373, France
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Centro Integral Oncologico Clara Campal
RECRUITINGMadrid, 28050, Spain
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Centro Ricerche Cliniche Di Verona
RECRUITINGVerona, 37134, Italy
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Dana Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
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Fondazione Irccs Istituto Nazionale Dei Tumori
RECRUITINGMilan, 20133, Italy
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Freeman Hospital Newcastle Upon Tyne Foundation Nhs Trust
RECRUITINGNewcastle upon Tyne, NE7 7DN, United Kingdom
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Fundacion Jimenez Diaz University Hospital
RECRUITINGMadrid, 28040, Spain
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Guys and St Thomas Nhs Foundation Trust
RECRUITINGLondon, SE1 9RT, United Kingdom
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Hackensack University Medical Center
RECRUITINGHackensack, New Jersey, 07601, United States
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Herlev Og Gentofte Hospital
RECRUITINGHerlev, 02730, Denmark
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Hospital General Universitario Vall D Hebron
RECRUITINGBarcelona, 08035, Spain
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Hospital Universitario 12 de Octubre
RECRUITINGMadrid, 28041, Spain
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Imperial College Healthcare Nhs Trust - Hammersmith Hospital
RECRUITINGLondon, W12 0HS, United Kingdom
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Institut Gustave Roussy
RECRUITINGVillejuif, 94805, France
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Irccs Istituto Clinico Humanitas
RECRUITINGRozzano, 20089, Italy
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Istituto Oncologico Della Svizzera Italiana
RECRUITINGBellinzona, 06500, Switzerland
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Kansai Medical University Hospital
RECRUITINGHirakata, 573-1191, Japan
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Kantonsspital St. Gallen
RECRUITINGSankt Gallen, 09007, Switzerland
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Laura and Isaac Perlmutter Cancer Center
RECRUITINGNew York, New York, 10016, United States
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Lifespan Cancer Research Institute
RECRUITINGProvidence, Rhode Island, 02903, United States
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National Cancer Center Hospital
RECRUITINGTokyo, 104-0045, Japan
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Nyu Langone Health - Long Island Hospital
RECRUITINGMineola, New York, 11501, United States
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Odense University Hospital
RECRUITINGOdense C, 05000, Denmark
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Rigshospitalet Uni of Hospital of Copenhagen
RECRUITINGCopenhagen, 02100, Denmark
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South Texas Accelerated Research Therapeutics
RECRUITINGSan Antonio, Texas, 78229, United States
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Start Barcelona
RECRUITINGBarcelona, 08023, Spain
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The Angeles Clinic and Research Institute
RECRUITINGLos Angeles, California, 90025, United States
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The Cancer Institute Hospital of Jfcr
RECRUITINGTokyo, 135-0063, Japan
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The Christie Nhs Foundation Trust Uk
RECRUITINGManchester, M20 4BV, United Kingdom
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University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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University of Texas Md Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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Valkyrie Clinical Trials
RECRUITINGLos Angeles, California, 90067, United States
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Vejle Hospital
RECRUITINGVejle, 07100, Denmark
Conditions
Explore the condition pages connected to this study.