Engineered immune cells take on Cancer-Related fluid swelling
NCT ID NCT07561437
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase trial is testing a new treatment called NK521 for people with advanced solid tumors that have spread and caused fluid buildup in the belly (malignant ascites). The treatment uses a person's own natural killer (NK) cells that have been gene-edited to better attack cancer. The study will enroll 18 adults who have tried at least two standard treatments without success. The main goal is to check safety, but researchers will also look for signs that the treatment controls the cancer or reduces the need for fluid drainage.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Gene-edited natural killer (NK) cells
What this could lead to
If successful, this could point toward a new way to control malignant ascites and improve quality of life in people with advanced solid tumors.
What could go wrong
This is a very early, small Phase 1 trial with only 18 participants, so it is primarily testing safety. The treatment may not shrink tumors or control ascites, and side effects are unknown.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Cancer Hospital, Chinese Academy of Medical Sciences
RECRUITINGBeijing, Beijing Municipality, 010, China
Contact Phone: •••-•••-•••• Email: •••••@•••••