New gene therapy targets tough cancers in early trial
NCT ID NCT07596693
First seen May 21, 2026 · Last updated Jun 23, 2026 · Updated 4 times
Summary
This early-phase study is testing a new treatment called KXV01 for people with advanced solid tumors, including sarcomas, who have no other options. The therapy uses a patient's own immune cells, modified with a virus to recognize and attack their specific tumor. The main goal is to check safety and find the right dose, with 30 participants expected.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Shanghai Sixth People's Hospital Affiliated to Shanghai Jiaotong University
RECRUITINGShanghai, 200233, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
KXV01 TCR Lentinvivo injection (a personalized gene therapy that trains immune cells to attack tumors)
What this could lead to
If it works, this could point toward a new treatment option for people with advanced solid tumors who have run out of standard therapies.
What could go wrong
This is a very early, small Phase 1 trial focused on safety, not proof of effectiveness. The therapy may cause serious side effects like cytokine release syndrome, and it may not shrink tumors or extend survival.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.