New drug combo targets Hard-to-Treat cancers
NCT ID NCT06697197
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests an experimental drug called BMS-986482, alone or combined with other cancer drugs, in people with advanced solid tumors that have not responded to standard treatments. The main goals are to check safety and find the right dose. About 413 adults will take part. The study is currently recruiting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
BMS-986482 (an experimental drug) given alone or with nivolumab, relatlimab, or bevacizumab
What this could lead to
If successful, this could point toward a new treatment option for people with advanced solid tumors that have not responded to other therapies.
What could go wrong
This is an early-phase trial (phase 1/2) with a primary focus on safety, so it is too soon to know if the drug will work. The study is small and may not lead to a proven treatment.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Locations
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Assistance Publique Hôpitaux de Marseille - Hôpital de la Timone
RECRUITINGMarseille, Bouches-du-Rhône, 13385, France
Contact Phone: •••-•••-••••
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Clinica Universidad de Navarra
RECRUITINGPamplona, Navarre, 31008, Spain
Contact Phone: •••-•••-••••
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Erasmus Medisch Centrum
RECRUITINGRotterdam, 3015 GD, Netherlands
Contact Phone: •••-•••-••••
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Fondazione IRCCS Istituto Nazionale dei Tumori
RECRUITINGMilan, Lombardy, 20133, Italy
Contact Phone: •••-•••-••••
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Fred Hutchinson Cancer Center
RECRUITINGSeattle, Washington, 98109, United States
Contact Phone: •••-•••-••••
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General Hospital of Athens "Laiko"
RECRUITINGAthens, Attikí, 11527, Greece
Contact Phone: •••-•••-••••
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Gustave Roussy
RECRUITINGVillejuif, Paris, 94800, France
Contact Phone: •••-•••-••••
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Hospital Universitari Vall d'Hebron
RECRUITINGBarcelona, Barcelona [Barcelona], 08035, Spain
Contact Phone: •••-•••-••••
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Hospital Universitario HM Sanchinarro
RECRUITINGMadrid, 28050, Spain
Contact Phone: •••-•••-••••
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Istituto Clinico Humanitas
RECRUITINGRozzano, Milano, 20089, Italy
Contact Phone: •••-•••-••••
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John Theurer Cancer Center at Hackensack University Medical Center
RECRUITINGHackensack, New Jersey, 07601, United States
Contact Phone: •••-•••-••••
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Karolinska Universitetssjukhuset Solna
RECRUITINGSolna, Stockholms Län [se-01], 171 64, Sweden
Contact Phone: •••-•••-••••
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Levine Cancer Institute
RECRUITINGCharlotte, North Carolina, 28204, United States
Contact Phone: •••-•••-••••
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Local Institution - 0008
NOT_YET_RECRUITINGAurora, Colorado, 80045, United States
Contact
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Nederlands Kanker Instituut Antoni van Leeuwenhoek (NKI AVL)
RECRUITINGAmsterdam, North Holland, 1066 CX, Netherlands
Contact Phone: •••-•••-••••
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Northwell Health/ RJ Zuckerberg Cancer Center
RECRUITINGLake Success, New York, 11042, United States
Contact Phone: •••-•••-••••
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Papageorgiou General Hospital of Thessaloniki
RECRUITINGThessaloniki, Thessaloníki, 564 29, Greece
Contact Phone: •••-•••-••••
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Rigshospitalet
RECRUITINGCopenhagen, Capital Region, DK-2100, Denmark
Contact Phone: •••-•••-••••
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The Angeles Clinic and Research Institute - West Los Angeles Office
RECRUITINGLos Angeles, California, 90025, United States
Contact Phone: •••-•••-••••
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UZ Gent
RECRUITINGGhent, Oost-Vlaanderen, 9000, Belgium
Contact Phone: •••-•••-••••
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University of California, Irvine (UCI) Health - UC Irvine Medical Center
RECRUITINGIrvine, California, 92612, United States
Contact Phone: •••-•••-••••