New drug targets Hard-to-Treat cancers with missing gene
NCT ID NCT07601243
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tests an oral drug called GS-2426 in people with advanced solid tumors that lack a gene called MTAP. The main goals are to check safety, find the best dose, and see how the body handles the drug. About 174 adults whose cancer has not responded to standard treatments will take part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
GS-2426 (oral drug)
What this could lead to
If successful, this could lead to a new treatment option for people with advanced solid tumors that have a specific genetic deletion (MTAP).
What could go wrong
This is an early Phase 1 trial focused on safety and dosing, not yet on effectiveness. The drug may not work or could cause side effects. Only people with a specific tumor type (MTAP-deleted) are eligible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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START Astera, LLC
RECRUITINGEast Brunswick, New Jersey, 08816, United States
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START San Antonio, LLC
RECRUITINGSan Antonio, Texas, 78229, United States