New Antibody-Drug conjugate targets Hard-to-Treat cancers

NCT ID NCT06224855

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 1 trial tests an experimental drug, DXC006, in people with advanced solid tumors (like small cell lung cancer and neuroblastoma) or blood cancers (like multiple myeloma) who have not responded to standard treatments. DXC006 is an antibody-drug conjugate designed to deliver a cancer-killing agent directly to tumor cells. The main goals are to check safety, find the right dose, and get an early look at whether it shrinks tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

DXC006 (an antibody-drug conjugate)

What this could lead to

If safe and effective, DXC006 could offer a new treatment option for people with advanced solid tumors or blood cancers who have run out of standard therapies.

What could go wrong

This is an early, first-in-human trial, so the drug may not work or could cause serious side effects. The results are preliminary and may not lead to a widely available treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hematopoietic and lymphoid cell neoplasm hematopoietic and lymphoid system neoplasm neoplasm neuroblastoma plasma cell myeloma small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Anhui Cancer Hospital

    RECRUITING

    Hefei, Anhui, 230031, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hunan Cancer Hospital

    RECRUITING

    Changsha, Hunan, 410013, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sun Yat-sen University Cancer Center

    RECRUITING

    Guangzhou, Guangdong, 510060, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Nanchang University

    RECRUITING

    Nanchang, Jiangxi, 330006, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Zhejiang Cancer Hospital

    RECRUITING

    Hangzhou, Zhejiang, 310022, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••