Can a simple blood test outsmart deadly fungal infections in blood cancer?

NCT ID NCT07763184

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This study is testing whether a blood test called metagenomic next-generation sequencing (mNGS) can accurately diagnose invasive fungal disease in people with blood cancers. These patients are at high risk for such infections, which are often hard to detect and can become severe. The trial will measure how sensitive and specific the test is compared to standard methods, potentially offering a faster and more comprehensive way to identify the infection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
metagenomic next-generation sequencing (mNGS) of peripheral blood
What this could lead to
If successful, this could lead to faster and more accurate diagnosis of invasive fungal infections in blood cancer patients, potentially improving treatment outcomes.
What could go wrong
This is a small, early-stage study. The test may not be accurate enough or may not work for all types of fungal infections. There is also a risk of false positives or negatives.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Nanfang Hospital, Southern Medical University

    Guangzhou, Guangdong, 510515, China

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