New combo therapy targets Hard-to-Treat cancers in early trial

NCT ID NCT06520488

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 33 times

Summary

This study tests a new drug, HRS-4642, combined with other cancer treatments in people with advanced solid tumors that have a specific KRAS G12D mutation. The goal is to find the safest dose and see if the combination shrinks tumors. About 118 adults aged 18-75 with good performance status are being recruited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Renji Hospital, Shanghai Jiao Tong University School of Medicine

    RECRUITING

    Shanghai, Shanghai Municipality, 200127, China

    Contact

Conditions

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