New cancer drug YL211 enters first human tests
NCT ID NCT06384352
First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times
Summary
This early-stage trial tests a new drug called YL211 in 155 people with advanced solid tumors who have no standard treatment options left. The study has three parts: first, finding a safe dose; then, confirming that dose; and finally, testing how well it works. The main goals are to check safety and see if tumors shrink.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
YL211 (an antibody-drug conjugate given intravenously)
What this could lead to
If successful, this could point toward a new treatment option for people with advanced solid tumors who have run out of standard therapies.
What could go wrong
This is a very early Phase 1 trial, so the drug may not be safe or effective. Side effects are unknown, and it will take years before any potential treatment is confirmed.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ADVANCED SOLID TUMOR are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
China-Japan Friendship Hospital
RECRUITINGBeijing, Beijing Municipality, 100029, China
Contact
-
Comprehensive Cancer Centers of Nevada (CCCN) - Central Valley
RECRUITINGLas Vegas, Nevada, 89169, United States
Contact
-
Florida Cancer Specialists & Research Institute (FCS) - Sarasota Cattlemen Office
RECRUITINGSarasota, Florida, 34232-6422, United States
Contact Email: •••••@•••••
Contact
-
Gosford Hospital
RECRUITINGGosford, New South Wales, 2250, Australia
Contact
-
Monash Health
RECRUITINGMelbourne, Australia
Contact Email: •••••@•••••
Contact
-
NEXT Oncology - Dallas
RECRUITINGIrving, Texas, 75039, United States
Contact Email: •••••@•••••
Contact
-
NEXT Oncology - Houston
RECRUITINGHouston, Texas, 77055, United States
Contact
-
NEXT San Antonio
RECRUITINGSan Antonio, Texas, 78229, United States
Contact Email: •••••@•••••
-
One Clinical Research - Nedlands
RECRUITINGNedlands, Western Australia, 6009, Australia
Contact
-
Princess Margaret Hospital
RECRUITINGToronto, Toronto, Canada
Contact Email: •••••@•••••
Contact
-
Sarah Cannon Research Institute (SCRI) at HealthONE
RECRUITINGDenver, Colorado, 80218-1238, United States
Contact Email: •••••@•••••
Contact
-
Sarah Cannon Research Institute at Florida Cancer Specialists
RECRUITINGOrlando, Florida, 32827, United States
Contact
Contact Email: •••••@•••••
-
Sun Yat-sen University Cancer Center
RECRUITINGGuangzhou, China
Contact Email: •••••@•••••
Contact
Contact
-
The First Affiliated Hospital - Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, 310003, China
Contact
-
The Ottawa Hospital - General Campus
RECRUITINGOttawa, Canada
Contact Email: •••••@•••••
Contact
-
The University of Texas - MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Email: •••••@•••••
-
University of Cincinnati Vontz Center for Molecular Studies
RECRUITINGCincinnati, Ohio, 45219, United States
Contact
-
University of Colorado Hospital - Anschutz Cancer Pavilion
RECRUITINGAurora, Colorado, 80045, United States
Contact
Contact Email: •••••@•••••
-
Wenzhou Medical University - The First Affiliated Hospital
RECRUITINGWenzhou, Zhejiang, 325000, China
Contact
-
West China Hospital, Sichuan University
RECRUITINGChengdu, China
Contact Email: •••••@•••••
Contact
-
Yale School of Medicine - Yale Cancer Center - Smilow Cancer Hospital Care Centers - North Haven
RECRUITINGNorth Haven, Connecticut, 06473-2142, United States
Contact Email: •••••@•••••
Contact