New drug duo aims to halt advanced cancers
NCT ID NCT05944224
First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 2 times
Summary
This study tests an experimental drug called SPH4336, given alone or with another drug (cadonilimab), in people with advanced solid tumors that cannot be removed by surgery. The goal is to see if the treatment can slow or stop cancer growth. About 63 participants will take part in this early-phase trial.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fudan University Shanghai Cancer Center
RECRUITINGShanghai, China
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Fujian Cancer Hospital
RECRUITINGFuzhou, Fujian, China
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Henan Cancer Hospital
RECRUITINGZhengzhou, He'nan, China
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Liaoning Cancer Hospital & Institute
RECRUITINGShenzhen, Liaoning, China
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Peking Union Medical College Hospital
RECRUITINGBeijing, China
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Peking University People's Hospital
RECRUITINGBeijing, China
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Shanghai Sixth People's Hospital
RECRUITINGShanghai, China
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The Central Hospital of Yongzhou
RECRUITINGYongzhou, Hunan, China
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The First Affiliated Hospital，Sun Yat-sen University
RECRUITINGGuangzhou, Guangdong, China
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The Second Affiliated Hospital Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, China
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Tianjin Medical University Cancer Institute & Hospital
RECRUITINGTianjin, China
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Union Hospital Tongji Medical College Huazhong University of Science and Technology
RECRUITINGWuhan, Hubei, China
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West China Hospital，Sichuan University
RECRUITINGChengdu, Sichuan, China
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Xiangya Hospital Central South University
RECRUITINGChangsha, Hunan, China
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Xijing Hospital
RECRUITINGXi’an, Shanxi, China
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Zhejiang cancer Hospital
RECRUITINGHangzhou, Zhejiang, China
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Other studies related to the condition(s) this trial covers.
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- Can a protein calm the immune System's overreaction to cancer treatment?