Shanghai Pharmaceuticals Holding Co., Ltd

This study tests a new tablet called SPH5030 in 150 adults with advanced HER2-positive solid tumors that have not responded to standard treatments or have no standard options. The main goal is to check the drug's safety, find the best dose, and see how the body processes it. Part…

This early-phase trial tests a new drug called B001 in 45 people with a rare autoimmune disease called NMOSD. The study aims to check if B001 is safe, how the body processes it, and whether it might help control the disease. Participants must have had at least one relapse in the …

This study tests a modified herpesvirus (T3011) combined with standard immunotherapy drugs (PD-1/PD-L1 inhibitors) in people with advanced solid tumors that have not responded to other treatments. The goal is to see if the combination is safe and can shrink tumors. About 68 parti…

This Phase 2 trial tests a new oral drug called SPH4336 combined with standard hormone therapy for people with HR-positive, HER2-negative breast cancer that has spread to the brain. The study aims to see if the combination can shrink brain tumors and control the disease. About 52…

This Phase II trial tests a drug called LT3001 in 300 people who have had an acute ischemic stroke. Participants receive either a high or low dose of LT3001 or a placebo by IV infusion within 24 hours of their stroke. The study aims to see if the drug is safe and helps improve re…

This study tests a new drug, T3011, in 42 people with advanced melanoma that has spread. The main goals are to check safety and see if tumors shrink. Participants must have measurable tumors and be in good overall health.

This study tests a new oral drug called SPH4336 combined with hormone therapy (letrozole or fulvestrant) in people with a common type of advanced breast cancer (HR-positive, HER2-negative) that has worsened after prior treatment. About 254 participants will receive either the dru…

This study tests an experimental drug called SPH4336, given alone or with another drug (cadonilimab), in people with advanced solid tumors that cannot be removed by surgery. The goal is to see if the treatment can slow or stop cancer growth. About 63 participants will take part i…

This early-stage trial is testing the safety of a new drug called SPH9788 in 94 healthy Chinese adults aged 18 to 45. Participants will receive either the drug or a placebo, and researchers will monitor for side effects and how the drug moves through the body. The goal is simply …

This early-phase study tests the safety of a new drug called SPH7854 in 111 healthy adults. Participants receive either the drug or a placebo, and researchers monitor side effects and how the drug moves through the body. The goal is to see if it is safe enough to test in people w…