Shanghai Pharmaceuticals Holding Co., Ltd

This study tests a new drug called SPH4336 combined with hormone therapy for people with a certain type of advanced breast cancer (HR-positive, HER2-negative) that has gotten worse after standard treatment. About 254 participants will receive the combination to see if it shrinks …

This study tests a new drug called SPH4336, either alone or combined with another drug (cadonilimab), in people with advanced solid tumors, including a type of fat tissue cancer (liposarcoma). The goal is to see if the treatment can slow or stop cancer growth. About 63 participan…

This study tests a new drug called LT3001 for people who have had a stroke caused by a blood clot. The goal is to see if it helps patients recover better and with fewer side effects. About 300 adults aged 18 to 80 who can start treatment within 24 hours of their stroke will take …

This early-phase study tests an experimental pill called SPH5030 in 150 people with advanced HER2-positive solid tumors that have not responded to standard treatments. The main goal is to check the drug's safety, find the best dose, and see how the body processes it. Participants…

This study tests a new treatment, T3011, in 42 people with advanced melanoma that has spread. The main goals are to check safety and see if tumors shrink. Participants must have measurable tumors and be in good overall health.

This study tests a new medicine called B001 in 45 adults with a specific type of NMOSD, a rare disease where the immune system attacks the nerves. The main goal is to check if B001 is safe and how the body processes it. Researchers will also look for early signs that it might hel…

This study tests a new treatment for people with advanced solid tumors that have not responded to other therapies. It combines a modified herpesvirus (T3011) with drugs that help the immune system attack cancer (PD-1/PD-L1 inhibitors). The goal is to see if the combination is saf…

This early-stage study is testing a new drug called SPH7854 in 111 healthy volunteers to see if it is safe and how the body processes it. The drug is being developed for inflammatory bowel disease, but this trial does not involve people with the condition. The main goal is to che…

This early-stage study tests the safety of a new drug called SPH9788 in healthy adults aged 18 to 45. Participants receive either the drug or a placebo, and researchers monitor for side effects and how the drug moves through the body. The goal is to gather safety information, not…