New drug B001 tested for rare autoimmune disease

NCT ID NCT05145361

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This early-phase trial tests a new drug called B001 in 45 people with a rare autoimmune disease called NMOSD. The study aims to check if B001 is safe, how the body processes it, and whether it might help control the disease. Participants must have had at least one relapse in the past year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

B001 injection

What this could lead to

If successful, this could point toward a new treatment option to control NMOSD and reduce relapses.

What could go wrong

This is a very early, small Phase 1b trial focused on safety and dosing. It may not show clear benefit, and side effects are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neuromyelitis optica

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Tiantan Hospital Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, 100050, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • First Hospital of Shanxi Medical University

    RECRUITING

    Taiyuan, Shanxi, 030001, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tangdu hospital,fourth military medical university

    RECRUITING

    Xi’an, Shanxi, 710038, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tianjin Medical University General Hospital

    RECRUITING

    Tianjin, Tianjin Municipality, 300052, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact