New pill shows promise for Hard-to-Treat HER2 cancers

NCT ID NCT05245058

Recruiting now Disease control Sponsor: Shanghai Pharmaceuticals Holding Co., Ltd Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new tablet called SPH5030 in 150 adults with advanced HER2-positive solid tumors that have not responded to standard treatments or have no standard options. The main goal is to check the drug's safety, find the best dose, and see how the body processes it. Participants must be in fairly good health (ECOG 0-1) and have measurable tumors.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HER2-POSITIVE ADVANCED SOLID TUMORS

Contacts and locations

Locations

Anhui provincial hospital
RECRUITING

Hefei, Anhui, China
Anyang Cancer Hospital
RECRUITING

Anyang, Henan, China
Cancer Hospital Chinese Academy of Medical Sciences
RECRUITING

Beijing, Beijing Municipality, 100021, China
Guangxi Cancer Hospital
RECRUITING

Nanning, Guangxi, China
Harbin Medical University Cancer Hospital
RECRUITING

Harbin, Heilongjiang, China
Henan Cancer Hospital
RECRUITING

Zhengzhou, Henan, China
Jiangsu Province Hospital
RECRUITING

Nanjing, Jiangsu, China
Linyi Cancer Hospital
RECRUITING

Linyi, Shandong, China
Sun Yat-sen University Cancer Center
RECRUITING

Guangzhou, Guangdong, China
The First Affiliated Hospital of Bengbu Medical University
RECRUITING

Bengbu, China
The First Affiliated Hospital of China Medical University
RECRUITING

Shenyang, Liaoning, China
The Fourth Hospital of Hebei Medical University
RECRUITING

Shijiazhuang, Hebei, China
The Second Affiliated Hospital of Xi'an Jiaotong University
RECRUITING

Xi’an, Shanxi, China
The second people's hospital of neijiang
RECRUITING

Neijiang, China
Tianjin Cancer Hospital Airport Hospital
RECRUITING

Tianjin, China
Tianjin Medical University Cancer Institute & Hospital
RECRUITING

Tianjin, Tianjin Municipality, 300181, China
Xiangyang Central Hospital
RECRUITING

Xiangyang, Hubei, China