Cancer-Fighting virus injected into tumors shows promise in early trial

NCT ID NCT06311578

Recruiting now Disease control Sponsor: Johnson & Johnson Enterprise Innovation Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This early-phase study tests a virus (JNJ-87704916) that is injected directly into tumors to kill cancer cells. It is being tested alone and with another drug (cetrelimab) in people with advanced solid tumors who have run out of standard treatments. The main goals are to check safety, find the best dose, and see if the virus can shrink tumors.

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Conditions

The condition(s) this trial relates to.

neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVANCED SOLID TUMORS NEOPLASMS

Contacts and locations

Locations

Centre Hospitalier de l'Universite de Montreal
RECRUITING

Montreal, Quebec, H2X 0A9, Canada
Fox Chase Cancer Center
SUSPENDED

Philadelphia, Pennsylvania, 19111, United States
Gustave Roussy
RECRUITING

Villejuif, 94805, France
Hosp Univ Fund Jimenez Diaz
RECRUITING

Madrid, 28040, Spain
Hosp Univ Hm Sanchinarro
RECRUITING

Madrid, 28050, Spain
Hosp Univ Vall D Hebron
RECRUITING

Barcelona, 08035, Spain
MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
NYU Langone Health
RECRUITING

New York, New York, 10016, United States
Toronto General Hospital
RECRUITING

Toronto, Ontario, M5G 2C4, Canada
UPMC Cancer Centers
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States

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