New drug combo shows promise for Hard-to-Treat cancers

NCT ID NCT05941507

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 22 times

Summary

This study tests a new drug called LCB84, which targets a protein (TROP2) on cancer cells, for people with advanced solid tumors that have stopped responding to standard treatments. The drug is given alone or with another drug that boosts the immune system. The goal is to find safe doses and see if the combination can shrink tumors or slow their growth.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ADVANCED SOLID TUMORS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cedars Sinai Medical Center

    RECRUITING

    Los Angeles, California, 90048, United States

    Contact

  • Dana Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Email: •••••@•••••

    Contact

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Mary Crowley Cancer Research

    RECRUITING

    Dallas, Texas, 75230, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Princess Margaret Cancer Centre

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tennessee Oncology

    NOT_YET_RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Texas Southwestern Medical Center

    NOT_YET_RECRUITING

    Dallas, Texas, 75390, United States

    Contact

Conditions

Explore the condition pages connected to this study.