New hope for advanced cancers: first human trial launches

NCT ID NCT06730750

First seen Nov 16, 2025 · Last updated Jun 13, 2026 · Updated 28 times

Summary

This study tests an experimental drug called BMS-986490, alone or with another drug (bevacizumab), in people with advanced solid tumors that have a specific marker (CEACAM5). The goal is to see if the drug is safe and works against the cancer. About 360 adults with colorectal or non-small cell lung cancer that has spread or cannot be removed will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • John Theurer Cancer Center at Hackensack University Medical Center

    RECRUITING

    Hackensack, New Jersey, 07601, United States

    Contact Phone: •••-•••-••••

  • Princess Margaret Cancer Centre

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

    Contact Phone: •••-•••-••••

  • START Midwest

    RECRUITING

    Grand Rapids, Michigan, 49546, United States

    Contact Phone: •••-•••-••••

  • Tasman Oncology Research

    RECRUITING

    Southport, Queensland, 4215, Australia

    Contact Phone: •••-•••-••••

  • UPMC Hillman Cancer Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

    Contact Phone: •••-•••-••••

  • USC/Norris Comprehensive Cancer Center

    RECRUITING

    Los Angeles, California, 90033, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.