Smart drug delivers chemo directly to cancer cells in new trial
NCT ID NCT07439094
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new drug called CKD-703 in people with advanced solid tumors or non-small cell lung cancer that has a specific protein (c-Met). The drug is designed to attach to cancer cells and release chemotherapy directly inside them, aiming to kill the cancer while reducing harm to healthy cells. The trial will enroll 140 adults and first check safety and dosing, then measure how well the drug shrinks tumors.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- CKD-703 (an antibody-drug conjugate that targets c-Met and delivers a chemotherapy drug directly to cancer cells)
- What this could lead to
- If successful, this could provide a new targeted treatment option for people with certain advanced cancers, especially non-small cell lung cancer that has stopped responding to standard therapies.
- What could go wrong
- This is an early-phase trial (Phase 1/2a) with a small number of participants, so the drug may not prove effective or may cause unexpected side effects. It is also only for people with specific genetic markers (c-Met), limiting who can benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Gabrail Cancer Center
RECRUITINGOhio City, Ohio, 44718, United States
Contact Email: •••••@•••••
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