New drug combo hopes to shrink advanced cancers

NCT ID NCT06413680

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 21 times

Summary

This study tests an experimental drug, REGN10597, alone or with another drug (cemiplimab) in people with advanced solid tumors like melanoma and kidney cancer. The goal is to see if the treatment is safe and can shrink tumors. About 240 adults whose cancer has worsened after standard treatments will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

  • Next Oncology

    RECRUITING

    San Antonio, Texas, 78229, United States

  • Northwell Health

    RECRUITING

    Lake Success, New York, 11042, United States

  • Start Midwest Cancer Research

    RECRUITING

    Grand Rapids, Michigan, 49546, United States

  • The Start Center for Cancer Care

    RECRUITING

    San Antonio, Texas, 78229, United States

  • USC Norris Comprehensive Cancer Center

    RECRUITING

    Los Angeles, California, 90089, United States

  • University of California San Francisco (UCSF)

    RECRUITING

    San Francisco, California, 94143, United States

  • University of Chicago

    RECRUITING

    Chicago, Illinois, 60637, United States

  • University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27514, United States

  • University of Pittsburgh Medical Center - Hillman Cancer Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

  • Yale School of Medicine

    RECRUITING

    North Haven, Connecticut, 06473, United States

Conditions

Explore the condition pages connected to this study.